AU474809B2 - 2-(3-substituted amino-2-hyddroxypropoxy)-3-substituted pyrazines - Google Patents

2-(3-substituted amino-2-hyddroxypropoxy)-3-substituted pyrazines

Info

Publication number
AU474809B2
AU474809B2 AU54939/73A AU5493973A AU474809B2 AU 474809 B2 AU474809 B2 AU 474809B2 AU 54939/73 A AU54939/73 A AU 54939/73A AU 5493973 A AU5493973 A AU 5493973A AU 474809 B2 AU474809 B2 AU 474809B2
Authority
AU
Australia
Prior art keywords
substituted
hyddroxypropoxy
pyrazines
amino
substituted amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU54939/73A
Other languages
English (en)
Other versions
AU5493973A (en
Inventor
KENDALL WASSON and LEONARD MAURICE WEINSTOCK BURTON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme IA Corp
Original Assignee
Merck Sharp and Dohme IA Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme IA Corp filed Critical Merck Sharp and Dohme IA Corp
Publication of AU5493973A publication Critical patent/AU5493973A/en
Application granted granted Critical
Publication of AU474809B2 publication Critical patent/AU474809B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU54939/73A 1972-05-05 1973-04-27 2-(3-substituted amino-2-hyddroxypropoxy)-3-substituted pyrazines Expired AU474809B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CACA141,471 1972-05-05
CA141,471A CA1001631A (en) 1972-05-05 1972-05-05 2-(3-substituted amino-2-hydroxy-propoxy)-3-substituted pyrazines and method for preparation

Publications (2)

Publication Number Publication Date
AU5493973A AU5493973A (en) 1974-10-31
AU474809B2 true AU474809B2 (en) 1976-08-05

Family

ID=4093189

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54939/73A Expired AU474809B2 (en) 1972-05-05 1973-04-27 2-(3-substituted amino-2-hyddroxypropoxy)-3-substituted pyrazines

Country Status (13)

Country Link
JP (1) JPS584026B2 (es)
AU (1) AU474809B2 (es)
BE (1) BE799099A (es)
CA (1) CA1001631A (es)
CH (1) CH580603A5 (es)
DE (1) DE2322362A1 (es)
ES (1) ES414321A1 (es)
FR (1) FR2183752B1 (es)
GB (1) GB1390329A (es)
HU (1) HU167634B (es)
NL (1) NL7305480A (es)
SE (1) SE398500B (es)
ZA (1) ZA733051B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR207133A1 (es) * 1973-02-20 1976-09-15 Ciba Geigy Ag Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano
JPS5839832B2 (ja) * 1974-02-20 1983-09-01 チバ ガイギ− アクチエンゲゼルシヤフト 新規ピラジン化合物の製法
US4060601A (en) * 1976-06-15 1977-11-29 Merck & Co., Inc. Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines
JP2830387B2 (ja) * 1990-06-08 1998-12-02 株式会社明電舎 タイヤ有効半径測定方法
KR0138005B1 (ko) * 1993-10-21 1998-05-15 김낙두 신규의 화학적 보호제(chemopreventive agent)및 그의 제조방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1473815A (fr) * 1962-11-16 1967-03-24 Nl Combinatie Chem Ind Procédé de préparation d'amines tertiaires et nouveaux composés ainsi obtenus

Also Published As

Publication number Publication date
HU167634B (es) 1975-11-28
FR2183752A1 (es) 1973-12-21
ES414321A1 (es) 1976-02-01
CA1001631A (en) 1976-12-14
DE2322362A1 (de) 1973-11-22
CH580603A5 (es) 1976-10-15
JPS4961181A (es) 1974-06-13
BE799099A (fr) 1973-11-05
GB1390329A (en) 1975-04-09
FR2183752B1 (es) 1976-03-05
AU5493973A (en) 1974-10-31
ZA733051B (en) 1974-12-24
NL7305480A (es) 1973-11-07
JPS584026B2 (ja) 1983-01-24
SE398500B (sv) 1977-12-27

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