AU3791799A - Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia - Google Patents
Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemiaInfo
- Publication number
- AU3791799A AU3791799A AU37917/99A AU3791799A AU3791799A AU 3791799 A AU3791799 A AU 3791799A AU 37917/99 A AU37917/99 A AU 37917/99A AU 3791799 A AU3791799 A AU 3791799A AU 3791799 A AU3791799 A AU 3791799A
- Authority
- AU
- Australia
- Prior art keywords
- hyperglycemia
- treatment
- insulin resistance
- acetic acids
- acids useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7659698A | 1998-05-12 | 1998-05-12 | |
US09076596 | 1998-05-12 | ||
PCT/US1999/010211 WO1999058519A1 (en) | 1998-05-12 | 1999-05-10 | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
Publications (1)
Publication Number | Publication Date |
---|---|
AU3791799A true AU3791799A (en) | 1999-11-29 |
Family
ID=22133037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU37917/99A Abandoned AU3791799A (en) | 1998-05-12 | 1999-05-10 | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1077965A1 (en) |
JP (1) | JP2002514636A (en) |
CN (1) | CN1308621A (en) |
AU (1) | AU3791799A (en) |
CA (1) | CA2331120A1 (en) |
WO (1) | WO1999058519A1 (en) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6498182B2 (en) | 2000-09-26 | 2002-12-24 | Biovitrum Ab | Compounds |
CA2437118A1 (en) | 2001-02-09 | 2002-08-22 | Merck & Co., Inc. | 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders |
TWI224101B (en) | 2001-06-20 | 2004-11-21 | Wyeth Corp | Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1) |
US7291639B2 (en) | 2001-06-20 | 2007-11-06 | Wyeth | Aryloxy-acetic acid compounds useful as inhibitors of plasminogen activator inhibitor-1 (PAI-1) |
DK1397130T3 (en) | 2001-06-20 | 2007-11-12 | Wyeth Corp | Substituted Indole Acid Derivatives as Inhibitors of Plasminogen Activator Inhibitor-1 (PAI-1) |
US20050065208A1 (en) * | 2001-07-20 | 2005-03-24 | Bodo Brandts | Benzofuranes and their use in the treatment of atrial fibrillation |
US6784205B2 (en) * | 2002-03-01 | 2004-08-31 | Sunesis Pharmaceuticals, Inc. | Compounds that modulate the activity of PTP-1B and TC-PTP |
BR0316584A (en) | 2002-12-10 | 2005-10-04 | Wyeth Corp | Substituted oxo-acetyl amino indole acetic acid derivatives as plasminogen activator inhibitor-1 inhibitors (parent-1) |
DE60306548T2 (en) | 2002-12-10 | 2007-06-21 | Wyeth | SUBSTITUTED 3-CARBONYL-1-YL-ACETIC DERIVATIVES AS PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) INHIBITORS |
UA80453C2 (en) | 2002-12-10 | 2007-09-25 | Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1) | |
JP2006510673A (en) | 2002-12-10 | 2006-03-30 | ワイス | Aryl, aryloxy and alkyloxy substituted 1H-indol-3-ylglyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor 1 (PAI-1) |
US7348351B2 (en) | 2002-12-10 | 2008-03-25 | Wyeth | Substituted 3-alkyl and 3-arylalkyl 1H-indol-1yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) |
US7141592B2 (en) | 2003-09-25 | 2006-11-28 | Wyeth | Substituted oxadiazolidinediones |
US7163954B2 (en) | 2003-09-25 | 2007-01-16 | Wyeth | Substituted naphthyl benzothiophene acids |
US7446201B2 (en) | 2003-09-25 | 2008-11-04 | Wyeth | Substituted heteroaryl benzofuran acids |
US7582773B2 (en) | 2003-09-25 | 2009-09-01 | Wyeth | Substituted phenyl indoles |
US7265148B2 (en) | 2003-09-25 | 2007-09-04 | Wyeth | Substituted pyrrole-indoles |
US7411083B2 (en) | 2003-09-25 | 2008-08-12 | Wyeth | Substituted acetic acid derivatives |
US7268159B2 (en) | 2003-09-25 | 2007-09-11 | Wyeth | Substituted indoles |
US7351726B2 (en) | 2003-09-25 | 2008-04-01 | Wyeth | Substituted oxadiazolidinediones |
US7332521B2 (en) | 2003-09-25 | 2008-02-19 | Wyeth | Substituted indoles |
US7442805B2 (en) | 2003-09-25 | 2008-10-28 | Wyeth | Substituted sulfonamide-indoles |
US7342039B2 (en) | 2003-09-25 | 2008-03-11 | Wyeth | Substituted indole oximes |
US7141596B2 (en) | 2003-10-08 | 2006-11-28 | Incyte Corporation | Inhibitors of proteins that bind phosphorylated molecules |
FR2862646B1 (en) | 2003-11-20 | 2006-02-24 | Merck Sante Sas | NOVEL ANTIDIABETIC COMPOUNDS CONTAINING BENZOFURAN, BENZOTHIOPHENIC DERIVATIVES |
FR2862645B1 (en) * | 2003-11-20 | 2007-06-22 | Merck Sante Sas | ANTIDIABETIC COMPOUNDS CONTAINING BENZOFURAN, BENZOTHIOPHENIC DERIVATIVES |
FR2864536B1 (en) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | PROCESS FOR THE PREPARATION OF N-ALKYL-2 (HYDROXY-4-BENZOYL) -3 BENZOFURANES AND INTERMEDIATES FOR CARRYING OUT SAID METHOD |
WO2006023865A1 (en) | 2004-08-23 | 2006-03-02 | Wyeth | Oxazolo-naphthyl acids as plaminogen activator inhibtor type-1 (pai-1) modulators useful in the treatment of thrombosis and cardiovascular diseases |
AU2006279496A1 (en) | 2005-08-17 | 2007-02-22 | Wyeth | Substituted indoles and use thereof |
WO2012048058A2 (en) * | 2010-10-06 | 2012-04-12 | J-Pharma Co., Ltd. | Developing potent urate transporter inhibitors: compounds designed for their uricosuric action |
CN102718735B (en) * | 2012-05-28 | 2014-04-23 | 沈阳药科大学 | 2-ethyl-3-(4-hydroxy) benzoyl benzofuran compounds and compositions and preparation methods of compounds |
EP3360870A1 (en) | 2013-02-19 | 2018-08-15 | Novartis AG | Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders |
CN108084186B (en) * | 2016-11-16 | 2021-06-25 | 江苏新元素医药科技有限公司 | URAT1 inhibitor and application thereof |
WO2023149549A1 (en) * | 2022-02-03 | 2023-08-10 | 国立大学法人富山大学 | Novel pharmaceutical composition |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3012042A (en) * | 1956-12-21 | 1961-12-05 | Belge Produits Chimiques Sa | Benzofurans |
DE3342624A1 (en) * | 1983-11-25 | 1984-03-29 | Heinfried Dr. 4019 Monheim Grote | Benzarone derivatives, process for their preparation and medicaments containing these derivatives |
FR2653431B1 (en) * | 1989-10-23 | 1994-05-27 | Sanofi Sa | PROCESS FOR THE PREPARATION OF BENZOYL-3 BENZOFURAN DERIVATIVES. |
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
SE9101509D0 (en) * | 1991-05-17 | 1991-05-17 | Karobio Ab | RECEPTOR LIGANDS |
DE4239429A1 (en) * | 1992-11-24 | 1994-05-26 | Merck Patent Gmbh | Process for the preparation of immunoconjugates |
GB9416219D0 (en) * | 1994-08-11 | 1994-10-05 | Karobio Ab | Receptor ligands |
AU2381397A (en) * | 1996-04-19 | 1997-11-12 | Novo Nordisk A/S | Modulators of molecules with phosphotyrosine recognition units |
DE19624292A1 (en) * | 1996-06-18 | 1998-01-02 | Merckle Gmbh | Preparation of optically pure 1'-hydroxy-benz-bromoarone |
-
1999
- 1999-05-10 WO PCT/US1999/010211 patent/WO1999058519A1/en not_active Application Discontinuation
- 1999-05-10 EP EP99920419A patent/EP1077965A1/en not_active Withdrawn
- 1999-05-10 CN CN99808361A patent/CN1308621A/en active Pending
- 1999-05-10 AU AU37917/99A patent/AU3791799A/en not_active Abandoned
- 1999-05-10 JP JP2000548323A patent/JP2002514636A/en active Pending
- 1999-05-10 CA CA002331120A patent/CA2331120A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1077965A1 (en) | 2001-02-28 |
CA2331120A1 (en) | 1999-11-18 |
CN1308621A (en) | 2001-08-15 |
WO1999058519A1 (en) | 1999-11-18 |
JP2002514636A (en) | 2002-05-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |