AU3536084A - Omega-cycloalkyl prostaglandins - Google Patents

Omega-cycloalkyl prostaglandins

Info

Publication number
AU3536084A
AU3536084A AU35360/84A AU3536084A AU3536084A AU 3536084 A AU3536084 A AU 3536084A AU 35360/84 A AU35360/84 A AU 35360/84A AU 3536084 A AU3536084 A AU 3536084A AU 3536084 A AU3536084 A AU 3536084A
Authority
AU
Australia
Prior art keywords
hydroxy
methyl
compound according
hept
cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU35360/84A
Other languages
English (en)
Inventor
Paul Waddell Collins
Alan Frank Gasiecki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of AU3536084A publication Critical patent/AU3536084A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU35360/84A 1983-11-14 1984-11-13 Omega-cycloalkyl prostaglandins Abandoned AU3536084A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/551,238 US4499296A (en) 1983-11-14 1983-11-14 Omega cycloalkyl prostaglandins
US551238 1995-10-31

Publications (1)

Publication Number Publication Date
AU3536084A true AU3536084A (en) 1985-05-23

Family

ID=24200423

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35360/84A Abandoned AU3536084A (en) 1983-11-14 1984-11-13 Omega-cycloalkyl prostaglandins

Country Status (16)

Country Link
US (1) US4499296A (enExample)
EP (1) EP0142158B1 (enExample)
JP (1) JPS60116667A (enExample)
AT (1) ATE39481T1 (enExample)
AU (1) AU3536084A (enExample)
DE (1) DE3475785D1 (enExample)
DK (1) DK538984A (enExample)
ES (1) ES8603400A1 (enExample)
FI (1) FI844460L (enExample)
GR (1) GR80926B (enExample)
IL (1) IL73501A (enExample)
NO (1) NO844528L (enExample)
NZ (1) NZ210197A (enExample)
PH (1) PH21604A (enExample)
PT (1) PT79488A (enExample)
ZA (1) ZA848840B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU588526B2 (en) * 1984-04-24 1989-09-21 Glaxo Group Limited Cyclopentyl ethers having PGE``-type activity, their preparation and pharmaceutical formulation
AU591920B2 (en) * 1985-07-29 1989-12-21 American Cyanamid Company Precursors and synthesis of methyl-9-oxo-11alpha, 16- dihydroxy-16-vinyl-5-cis-13-trans-prostadienoates
AU602867B2 (en) * 1985-07-19 1990-11-01 Schering Aktiengesellschaft Berlin Und Bergkamen Prostacyclines, their analogues or prostaglandines and thromboxane antagonists for the treatment of thrombotic and thrombo-embolic illnesses
AU633697B2 (en) * 1990-02-26 1993-02-04 Sucampo Ag New 15-dehydroxy-16-oxoprostaglandins

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713477A (en) * 1983-11-14 1987-12-15 G. D. Searle & Co. Omega cycloalkyl prostaglandins
US4683328A (en) * 1985-11-25 1987-07-28 G. D. Searle & Co. Tetraenyl prostaglandins
US4847293A (en) * 1985-11-25 1989-07-11 G. D. Searle & Co. Tetraenyl prostaglandins
US4820728A (en) * 1985-11-25 1989-04-11 G. D. Searle & Co. Tetraenyl prostaglandins
US4785124A (en) * 1987-06-08 1988-11-15 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US5011958A (en) * 1987-06-08 1991-04-30 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US4777275A (en) * 1987-06-09 1988-10-11 G. D. Searle & Co. Process of preparing higher order cuprate complexes
US5177251A (en) * 1991-12-24 1993-01-05 G. D. Searle & Co. Halogenated tetraenyl prostaglandin derivatives
JP2531341Y2 (ja) * 1993-02-25 1997-04-02 小糸工業株式会社 衛生洗浄装置におけるワイヤレスリモコン装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3965143A (en) * 1974-03-26 1976-06-22 G. D. Searle & Co. 16-Oxygenated prostanoic acid derivatives
US4281153A (en) * 1977-08-01 1981-07-28 American Cyanamid 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
US4275224A (en) * 1978-02-23 1981-06-23 Miles Laboratories, Inc. 15-Deoxy-16-hydroxy prostaglandins
US4271314A (en) * 1979-11-28 1981-06-02 G. D. Searle & Co. 4,5-Unsaturated prostanoic acid derivatives

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU588526B2 (en) * 1984-04-24 1989-09-21 Glaxo Group Limited Cyclopentyl ethers having PGE``-type activity, their preparation and pharmaceutical formulation
AU602867B2 (en) * 1985-07-19 1990-11-01 Schering Aktiengesellschaft Berlin Und Bergkamen Prostacyclines, their analogues or prostaglandines and thromboxane antagonists for the treatment of thrombotic and thrombo-embolic illnesses
AU591920B2 (en) * 1985-07-29 1989-12-21 American Cyanamid Company Precursors and synthesis of methyl-9-oxo-11alpha, 16- dihydroxy-16-vinyl-5-cis-13-trans-prostadienoates
AU633697B2 (en) * 1990-02-26 1993-02-04 Sucampo Ag New 15-dehydroxy-16-oxoprostaglandins

Also Published As

Publication number Publication date
ES537613A0 (es) 1985-12-16
ATE39481T1 (de) 1989-01-15
JPS60116667A (ja) 1985-06-24
DK538984D0 (da) 1984-11-13
NZ210197A (en) 1988-04-29
EP0142158B1 (en) 1988-12-28
FI844460A0 (fi) 1984-11-13
JPH0576467B2 (enExample) 1993-10-22
GR80926B (en) 1985-02-26
DK538984A (da) 1985-05-15
EP0142158A2 (en) 1985-05-22
IL73501A0 (en) 1985-02-28
FI844460A7 (fi) 1985-05-15
EP0142158A3 (en) 1986-09-03
DE3475785D1 (en) 1989-02-02
PT79488A (en) 1984-12-01
PH21604A (en) 1987-12-11
NO844528L (no) 1985-05-15
ES8603400A1 (es) 1985-12-16
FI844460L (fi) 1985-05-15
US4499296A (en) 1985-02-12
IL73501A (en) 1987-12-31
ZA848840B (en) 1985-12-24

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