AU3288484A - Chemical intermediates - Google Patents

Chemical intermediates

Info

Publication number
AU3288484A
AU3288484A AU32884/84A AU3288484A AU3288484A AU 3288484 A AU3288484 A AU 3288484A AU 32884/84 A AU32884/84 A AU 32884/84A AU 3288484 A AU3288484 A AU 3288484A AU 3288484 A AU3288484 A AU 3288484A
Authority
AU
Australia
Prior art keywords
chemical intermediates
intermediates
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU32884/84A
Other versions
AU563015B2 (en
Inventor
Alain Martel
Marcel Menard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of AU3288484A publication Critical patent/AU3288484A/en
Application granted granted Critical
Publication of AU563015B2 publication Critical patent/AU563015B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568Four-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6539Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65611Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. penicillins and analogs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU32884/84A 1978-12-18 1984-09-10 Chemical intermediates Ceased AU563015B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96866378A 1978-12-18 1978-12-18
US968663 1978-12-18

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU53710/79A Division AU541717B2 (en) 1978-12-18 1979-12-11 2-substituted and 2,6-disubstituted penem antibiotics

Publications (2)

Publication Number Publication Date
AU3288484A true AU3288484A (en) 1985-03-07
AU563015B2 AU563015B2 (en) 1987-06-25

Family

ID=25514601

Family Applications (4)

Application Number Title Priority Date Filing Date
AU53710/79A Ceased AU541717B2 (en) 1978-12-18 1979-12-11 2-substituted and 2,6-disubstituted penem antibiotics
AU53787/79A Ceased AU539983B2 (en) 1978-12-18 1979-12-13 2-penem antibiotics
AU32408/84A Ceased AU557545B2 (en) 1978-12-18 1984-08-24 Intermediates for 2-penems
AU32884/84A Ceased AU563015B2 (en) 1978-12-18 1984-09-10 Chemical intermediates

Family Applications Before (3)

Application Number Title Priority Date Filing Date
AU53710/79A Ceased AU541717B2 (en) 1978-12-18 1979-12-11 2-substituted and 2,6-disubstituted penem antibiotics
AU53787/79A Ceased AU539983B2 (en) 1978-12-18 1979-12-13 2-penem antibiotics
AU32408/84A Ceased AU557545B2 (en) 1978-12-18 1984-08-24 Intermediates for 2-penems

Country Status (13)

Country Link
JP (1) JPS60222486A (en)
AU (4) AU541717B2 (en)
CA (2) CA1286661C (en)
CH (2) CH643265A5 (en)
DK (5) DK533879A (en)
ES (1) ES487034A0 (en)
FI (2) FI67853C (en)
GR (2) GR81420B (en)
IE (3) IE50597B1 (en)
IL (2) IL58576A (en)
SE (5) SE448995B (en)
YU (4) YU43628B (en)
ZA (2) ZA796813B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8509180D0 (en) * 1985-04-10 1985-05-15 Erba Farmitalia Penem derivatives
US4826832A (en) * 1986-05-06 1989-05-02 Ciba-Geigy Corporation Penen compounds
WO1996025417A1 (en) * 1995-02-17 1996-08-22 Suntory Limited Penem derivatives and antimicrobial agent containing the same
KR20000076105A (en) 1998-01-13 2000-12-26 도리이 신이찌로 Antibacterial composition for topical administration containing antibiotics
JP2005239696A (en) 2004-01-30 2005-09-08 Daiichi Suntory Pharma Co Ltd Medicinal hard capsule preparation blended with inorganic substance
CN112746066B (en) * 2021-01-25 2023-10-31 洛阳华荣生物技术有限公司 L-lysine decarboxylase mutant and application thereof

Also Published As

Publication number Publication date
DK236590A (en) 1990-10-01
IE49876B1 (en) 1986-01-08
FI67853B (en) 1985-02-28
SE8405812D0 (en) 1984-11-19
IL58576A (en) 1985-12-31
ES8101594A1 (en) 1980-12-16
AU541717B2 (en) 1985-01-17
YU42125B (en) 1988-04-30
YU43280B (en) 1989-06-30
FI793905A (en) 1980-06-19
DK533779A (en) 1980-06-19
AU557545B2 (en) 1986-12-24
IE50597B1 (en) 1986-05-28
ZA796813B (en) 1981-05-27
SE461395B (en) 1990-02-12
IL58804A0 (en) 1980-02-29
IL58804A (en) 1986-03-31
FI793903A (en) 1980-06-19
GR81420B (en) 1984-12-11
SE454779B (en) 1988-05-30
CA1286661C (en) 1991-07-23
SE448995B (en) 1987-03-30
GR74491B (en) 1984-06-28
DK237690D0 (en) 1990-10-01
AU3240884A (en) 1984-12-13
YU215782A (en) 1983-06-30
DK161970C (en) 1992-02-03
CH643846A5 (en) 1984-06-29
SE8405719L (en) 1984-11-14
DK236590D0 (en) 1990-10-01
CA1268183A (en) 1990-04-24
IE49877B1 (en) 1986-01-08
AU539983B2 (en) 1984-10-25
DK533879A (en) 1980-06-19
IE851853L (en) 1980-06-18
SE7910391L (en) 1981-06-18
YU276079A (en) 1983-02-28
SE464027B (en) 1991-02-25
YU43464B (en) 1989-08-31
FI67853C (en) 1985-06-10
AU5378779A (en) 1980-08-28
SE7910390L (en) 1981-06-18
YU43628B (en) 1989-10-31
AU563015B2 (en) 1987-06-25
SE8405812L (en) 1984-11-19
ES487034A0 (en) 1980-12-16
IE852246L (en) 1980-06-18
CH643265A5 (en) 1984-05-30
DK237690A (en) 1990-10-01
SE8405813D0 (en) 1984-11-19
DK161520C (en) 1991-12-23
DK135291D0 (en) 1991-07-15
FI69845B (en) 1985-12-31
AU5371079A (en) 1980-06-26
FI69845C (en) 1986-05-26
DK161520B (en) 1991-07-15
ZA796812B (en) 1981-05-27
DK135291A (en) 1991-07-15
JPS60222486A (en) 1985-11-07
IL58576A0 (en) 1980-01-31
SE8405813L (en) 1984-11-19
DK161970B (en) 1991-09-02
SE8405719D0 (en) 1984-11-14
IE792462L (en) 1980-06-18
YU215382A (en) 1983-06-30
YU307679A (en) 1983-02-28

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