AU3192389A - Novel diazines and their method of preparation - Google Patents

Novel diazines and their method of preparation

Info

Publication number
AU3192389A
AU3192389A AU31923/89A AU3192389A AU3192389A AU 3192389 A AU3192389 A AU 3192389A AU 31923/89 A AU31923/89 A AU 31923/89A AU 3192389 A AU3192389 A AU 3192389A AU 3192389 A AU3192389 A AU 3192389A
Authority
AU
Australia
Prior art keywords
diazines
novel
preparation
novel diazines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU31923/89A
Inventor
Donald B. Harden
Maria Mokrosz
Lucjan Strekowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgia State University Research Foundation Inc
Original Assignee
Georgia State University Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Georgia State University Research Foundation Inc filed Critical Georgia State University Research Foundation Inc
Publication of AU3192389A publication Critical patent/AU3192389A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
AU31923/89A 1988-02-09 1989-02-02 Novel diazines and their method of preparation Abandoned AU3192389A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/153,998 US4929726A (en) 1988-02-09 1988-02-09 Novel diazines and their method of preparation
US153998 1988-02-09

Publications (1)

Publication Number Publication Date
AU3192389A true AU3192389A (en) 1989-09-06

Family

ID=22549605

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31923/89A Abandoned AU3192389A (en) 1988-02-09 1989-02-02 Novel diazines and their method of preparation

Country Status (3)

Country Link
US (2) US4929726A (en)
AU (1) AU3192389A (en)
WO (1) WO1989007599A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0358609B1 (en) * 1988-09-09 1996-07-24 Ciba-Geigy Ag Parasiticide compounds
US5175293A (en) * 1988-09-09 1992-12-29 Ciba-Geigy Corporation Pesticides
TW440563B (en) * 1996-05-23 2001-06-16 Hoffmann La Roche Aryl pyrimidine derivatives and a pharmaceutical composition thereof
US5952331A (en) * 1996-05-23 1999-09-14 Syntex (Usa) Inc. Aryl pyrimidine derivatives
US5958934A (en) * 1996-05-23 1999-09-28 Syntex (U.S.A.) Inc. Aryl pyrimidine derivatives and uses thereof
CA2321153A1 (en) 1998-02-17 1999-08-19 Timothy D. Cushing Anti-viral pyrimidine derivatives
US6410726B1 (en) 2000-01-12 2002-06-25 Tularik Inc. Arylsulfonic acid salts of pyrimidine-based antiviral
AU2003295776B2 (en) * 2002-11-21 2011-05-12 Novartis Vaccines And Diagnostics, Inc. 2,4,6-trisubstituted pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer
JO2660B1 (en) 2006-01-20 2012-06-17 نوفارتيس ايه جي PI-3 Kinase inhibitors and methods of their use
PT2125794E (en) 2006-12-21 2011-01-10 Lilly Co Eli Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
EA016177B1 (en) 2006-12-21 2012-02-28 Эли Лилли Энд Компани Imidazolidinonyl aminopyrimidine compounds for the treatment' of cancer
CA2675558A1 (en) * 2007-02-06 2008-08-14 Novartis Ag Pi 3-kinase inhibitors and methods of their use
AR066473A1 (en) * 2007-05-16 2009-08-19 Lilly Co Eli TRIAZOLIL AMINOPIRIMIDINE COMPOSITE, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT AND ITS USE TO PREPARE A USEFUL MEDICINAL PRODUCT TO TREAT CANCER
KR101131254B1 (en) * 2007-05-16 2012-04-24 일라이 릴리 앤드 캄파니 Triazolyl aminopyrimidine compounds
WO2009066084A1 (en) * 2007-11-21 2009-05-28 F. Hoffmann-La Roche Ag 2 -morpholinopyrimidines and their use as pi3 kinase inhibitors
AU2010339531A1 (en) 2009-12-30 2012-08-23 Arqule, Inc. Substituted naphthalenyl-pyrimidine compounds
PE20141581A1 (en) 2011-09-27 2014-11-14 Novartis Ag 3-PIRMIDIN-4-IL-OXAZOLIDIN-2-ONAS AS INHIBITORS OF MUTANT HDI
UY34632A (en) 2012-02-24 2013-05-31 Novartis Ag OXAZOLIDIN- 2- ONA COMPOUNDS AND USES OF THE SAME
US9296733B2 (en) 2012-11-12 2016-03-29 Novartis Ag Oxazolidin-2-one-pyrimidine derivative and use thereof for the treatment of conditions, diseases and disorders dependent upon PI3 kinases
ES2665619T3 (en) 2013-03-14 2018-04-26 Novartis Ag 3-Pyrimidin-4-yl-oxazolidin-2-ones as mutant HDI inhibitors
CN110407757A (en) * 2019-06-24 2019-11-05 南京普锐达医药科技有限公司 A kind of synthetic method of 4,5,6- Triaminopyrimidine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE491133C (en) * 1930-02-06 Caspar Fleuster Control for single-axis motor attachments, in particular beet lifters
US1355126A (en) * 1916-12-16 1920-10-12 Gen Electric X-ray tube
CH366550A (en) * 1958-05-13 1963-01-15 Hydrierwerk Rodleben Veb Process for the production of basic substituted phthalazines
CH491133A (en) * 1966-11-21 1970-05-31 Sandoz Ag Process for making new quinazolinones
GB1303061A (en) * 1969-05-03 1973-01-17
US4139633A (en) * 1971-06-15 1979-02-13 Ciba-Geigy Corporation Pharmaceutical preparations for the treatment of hypertonia
GB1385563A (en) * 1972-06-15 1975-02-26 Aspro Nicholas Ltd Aminophthalazine derivatives and pharmaceutical uses thereof
US4139622A (en) * 1977-10-20 1979-02-13 Olin Corporation Method of controlling fungi using phthalazine compounds
DOP1981004033A (en) * 1980-12-23 1990-12-29 Ciba Geigy Ag PROCEDURE TO PROTECT CROP PLANTS FROM PHYTOTOXIC ACTION OF HERBICIDES.
DE3379544D1 (en) * 1982-06-08 1989-05-11 Ciba Geigy Ag 2-phenyl-2-naphthyl and 2-heterocyclic pyrimidines as antidotes for protecting cultured plants before phytotoxic damages caused by herbicides

Also Published As

Publication number Publication date
WO1989007599A2 (en) 1989-08-24
WO1989007599A3 (en) 1989-10-19
US5304647A (en) 1994-04-19
US4929726A (en) 1990-05-29

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