AU3042597A - Serine protease inhibitors - Google Patents

Serine protease inhibitors

Info

Publication number
AU3042597A
AU3042597A AU30425/97A AU3042597A AU3042597A AU 3042597 A AU3042597 A AU 3042597A AU 30425/97 A AU30425/97 A AU 30425/97A AU 3042597 A AU3042597 A AU 3042597A AU 3042597 A AU3042597 A AU 3042597A
Authority
AU
Australia
Prior art keywords
protease inhibitors
serine protease
serine
inhibitors
protease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU30425/97A
Other versions
AU729393C (en
AU729393B2 (en
Inventor
John Joseph Deadman
Said Elgendy
Christopher Andrew Goodwin
Donovan Green
Vijay Vir Kakkar
Michael Finbarr Scully
Emmanuel Skordalakes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Trigen Ltd
Original Assignee
Trigen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trigen Ltd filed Critical Trigen Ltd
Publication of AU3042597A publication Critical patent/AU3042597A/en
Application granted granted Critical
Publication of AU729393B2 publication Critical patent/AU729393B2/en
Publication of AU729393C publication Critical patent/AU729393C/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU30425/97A 1996-06-29 1997-06-11 Serine protease inhibitors Ceased AU729393C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9613719.5A GB9613719D0 (en) 1996-06-29 1996-06-29 Serine protease inhibitors
GB9613719 1996-06-29
PCT/GB1997/001574 WO1998000442A1 (en) 1996-06-29 1997-06-11 Serine protease inhibitors
CN97195991A CN1223664A (en) 1996-06-29 1997-06-11 Serine protease inhibitors

Publications (3)

Publication Number Publication Date
AU3042597A true AU3042597A (en) 1998-01-21
AU729393B2 AU729393B2 (en) 2001-02-01
AU729393C AU729393C (en) 2002-05-16

Family

ID=40243006

Family Applications (1)

Application Number Title Priority Date Filing Date
AU30425/97A Ceased AU729393C (en) 1996-06-29 1997-06-11 Serine protease inhibitors

Country Status (9)

Country Link
EP (1) EP0935611A1 (en)
JP (1) JP2000516202A (en)
KR (1) KR20000022350A (en)
CN (1) CN1223664A (en)
AU (1) AU729393C (en)
CA (1) CA2258634A1 (en)
GB (1) GB9613719D0 (en)
NZ (1) NZ333390A (en)
WO (1) WO1998000442A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0405267D0 (en) * 2004-03-09 2004-04-21 Trigen Ltd Compounds
WO2009042922A2 (en) * 2007-09-27 2009-04-02 Amylin Pharmaceuticals, Inc. Peptide-peptidase inhibitor conjugates and methods of making and using same
WO2021074430A1 (en) * 2019-10-18 2021-04-22 Basf Se Storage-stable hydrolase containing liquids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240913A (en) * 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin

Also Published As

Publication number Publication date
NZ333390A (en) 1999-11-29
AU729393C (en) 2002-05-16
CA2258634A1 (en) 1998-01-08
CN1223664A (en) 1999-07-21
EP0935611A1 (en) 1999-08-18
KR20000022350A (en) 2000-04-25
AU729393B2 (en) 2001-02-01
GB9613719D0 (en) 1996-08-28
JP2000516202A (en) 2000-12-05
WO1998000442A1 (en) 1998-01-08

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE PROPOSED AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20010802

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS WAS NOTIFIED IN THE OFFICIAL JOURNAL DATED 20011108

MK14 Patent ceased section 143(a) (annual fees not paid) or expired