AU2170901A - Branched compound for use in nucleic acid detection and analysis reactions - Google Patents

Branched compound for use in nucleic acid detection and analysis reactions

Info

Publication number
AU2170901A
AU2170901A AU21709/01A AU2170901A AU2170901A AU 2170901 A AU2170901 A AU 2170901A AU 21709/01 A AU21709/01 A AU 21709/01A AU 2170901 A AU2170901 A AU 2170901A AU 2170901 A AU2170901 A AU 2170901A
Authority
AU
Australia
Prior art keywords
nucleic acid
acid detection
branched compound
analysis reactions
reactions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU21709/01A
Other languages
English (en)
Inventor
Reinhold Hiller
Martin Huber
Manfred Muller
Wolfgang Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sygnis Pharma AG
Original Assignee
Lion Bioscience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP99125484A external-priority patent/EP1111068A1/fr
Priority claimed from EP99125485A external-priority patent/EP1110967A1/fr
Application filed by Lion Bioscience AG filed Critical Lion Bioscience AG
Publication of AU2170901A publication Critical patent/AU2170901A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Structural Engineering (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU21709/01A 1999-12-21 2000-12-21 Branched compound for use in nucleic acid detection and analysis reactions Abandoned AU2170901A (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP99125484 1999-12-21
EP99125484A EP1111068A1 (fr) 1999-12-21 1999-12-21 Composé ramifié pour l'utilisation dans des réactions d'analyse et de détection des acides nucléiques
EP99125485 1999-12-21
EP99125485A EP1110967A1 (fr) 1999-12-21 1999-12-21 Composé comprenant un biomolecule et un organosilane
US21121700P 2000-06-13 2000-06-13
US21120900P 2000-06-13 2000-06-13
US60211209 2000-06-13
US60211217 2000-06-13
PCT/EP2000/013098 WO2001046464A1 (fr) 1999-12-21 2000-12-21 Compose ramifie s'utilisant dans des reactions de detection et d'analyse d'acide nucleique

Publications (1)

Publication Number Publication Date
AU2170901A true AU2170901A (en) 2001-07-03

Family

ID=56290094

Family Applications (3)

Application Number Title Priority Date Filing Date
AU31631/01A Abandoned AU3163101A (en) 1999-12-21 2000-12-21 Compound comprising a nucleic acid moiety and an organo-silane moiety
AU21709/01A Abandoned AU2170901A (en) 1999-12-21 2000-12-21 Branched compound for use in nucleic acid detection and analysis reactions
AU28432/01A Abandoned AU2843201A (en) 1999-12-21 2000-12-21 Compound comprising a peptide moiety and an organo-silane moiety.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU31631/01A Abandoned AU3163101A (en) 1999-12-21 2000-12-21 Compound comprising a nucleic acid moiety and an organo-silane moiety

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU28432/01A Abandoned AU2843201A (en) 1999-12-21 2000-12-21 Compound comprising a peptide moiety and an organo-silane moiety.

Country Status (3)

Country Link
EP (3) EP1252172A2 (fr)
AU (3) AU3163101A (fr)
WO (3) WO2001046464A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005241112B2 (en) * 2001-07-13 2009-07-30 Nanosphere, Inc. Method for preparing substrates having immobilized molecules and substrates
ATE495826T1 (de) 2002-05-20 2011-02-15 Danisco Us Inc Synthese von anorganischen strukturen unter verwendung von templates und katalyse durch selbstangeordnete repeat-protein-polymere
ATE486043T1 (de) 2002-05-20 2010-11-15 Danisco Us Inc Peptidderivate und deren verwendung zur synthese von verbundwerkstoffen auf siliciumbasis
US7534621B2 (en) 2003-02-07 2009-05-19 Canon Kabuhsiki Kashia Method of producing probe medium and method of immobilizing probe using probe medium
US20050142094A1 (en) 2003-03-12 2005-06-30 Manoj Kumar Use of repeat sequence protein polymers in personal care compositions
US7297678B2 (en) 2003-03-12 2007-11-20 Genencor International, Inc. Use of repeat sequence protein polymers in personal care compositions
WO2004104021A2 (fr) 2003-05-14 2004-12-02 Dow Corning Corporation Liberation controlee d'agents actifs a l'aide de polymeres proteiques a sequences repetees
CA2524707A1 (fr) 2003-05-14 2004-12-02 Dow Corning Corporation Conjugues a base d'agents actifs et de polymeres proteiques a sequences repetees, leurs procedes de fabrication et leurs applications
CA2552007A1 (fr) 2003-12-29 2005-07-21 Nugen Technologies, Inc. Methodes permettant d'analyser l'etat de methylation d'acides nucleiques et methodes permettant de fragmenter, de marquer et d'immobiliser des acides nucleiques
US7940746B2 (en) 2004-08-24 2011-05-10 Comcast Cable Holdings, Llc Method and system for locating a voice over internet protocol (VoIP) device connected to a network
SG10201510189WA (en) 2011-10-19 2016-01-28 Nugen Technologies Inc Compositions And Methods For Directional Nucleic Acid Amplification And Sequencing
WO2013072408A1 (fr) * 2011-11-15 2013-05-23 Swetree Technologies Ab Fibres cellulosiques à surface fonctionnalisée, procédé de fabrication associé et application associée
WO2013112923A1 (fr) 2012-01-26 2013-08-01 Nugen Technologies, Inc. Compositions et procédés pour l'enrichissement en séquence d'acide nucléique ciblée et la génération d'une banque à efficacité élevée
EP2861787B1 (fr) 2012-06-18 2017-09-20 Nugen Technologies, Inc. Compositions et procédés pour la sélection négative de séquences d'acide nucléique indésirable
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
EP2971130A4 (fr) 2013-03-15 2016-10-05 Nugen Technologies Inc Séquençage séquentiel
JP6525473B2 (ja) 2013-11-13 2019-06-05 ニューゲン テクノロジーズ， インコーポレイテッド 複製物配列決定リードを同定するための組成物および方法
WO2015131107A1 (fr) 2014-02-28 2015-09-03 Nugen Technologies, Inc. Séquençage au bisulfite de représentation réduite avec adaptateurs de diversité
SG11201700891SA (en) 2014-08-06 2017-03-30 Nugen Technologies Inc Digital measurements from targeted sequencing
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
CN113275053A (zh) 2020-02-03 2021-08-20 帝肯基因组学公司 试剂存储系统

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS608745B2 (ja) * 1978-02-14 1985-03-05 三洋化成工業株式会社 免疫活性物質−つや消しガラス複合体，その製造法及び該複合体を含有してなる測定試薬
US4284553A (en) * 1980-06-20 1981-08-18 North Carolina State University At Raleigh Reversible method for covalent immobilization of biochemicals
IL78678A0 (en) * 1986-05-04 1986-08-31 Yeda Res & Dev Substituted silica
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
GB9104453D0 (en) * 1991-03-02 1991-04-17 Tepnel Medical Ltd Improvements relating to enzymes
US5290440A (en) * 1992-06-23 1994-03-01 Research Corporation Technologies, Inc. High performance chiral selector
US5641658A (en) * 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
FR2726286B1 (fr) * 1994-10-28 1997-01-17 Genset Sa Procede d'amplification d'acides nucleiques en phase solide et trousse de reactifs utile pour la mise en oeuvre de ce procede
AU5871196A (en) * 1995-05-23 1996-12-24 Hybridon, Inc. Methods and compounds for the synthesis of oligonucleotides and the oligonucleotides thereby produced
US5912332A (en) * 1996-07-26 1999-06-15 Hybridon, Inc. Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides
US5916750A (en) * 1997-01-08 1999-06-29 Biogenex Laboratories Multifunctional linking reagents for synthesis of branched oligomers
ATE225858T1 (de) * 1997-07-28 2002-10-15 Medical Biosystems Ltd Sequenzanalyse von nukleinsäuren
AU9127898A (en) * 1997-09-02 1999-03-22 Isis Pharmaceuticals, Inc. Compositions and methods for the identification and quantitation of deletion sequence oligonucleotides in synthetic oligonucleotide preparations
JP2002510505A (ja) * 1998-04-03 2002-04-09 フィロス インク． 位置特定可能な蛋白質アレイ
US6048695A (en) * 1998-05-04 2000-04-11 Baylor College Of Medicine Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
DE19825899A1 (de) * 1998-06-10 1999-12-16 Memorec Medical Molecular Rese Vorrichtung zur parallelen Identifizierung und Quantifizierung von Polynukleinsäuren

Also Published As

Publication number Publication date
EP1250344A2 (fr) 2002-10-23
AU3163101A (en) 2001-07-03
EP1252172A2 (fr) 2002-10-30
AU2843201A (en) 2001-07-03
WO2001046464A1 (fr) 2001-06-28
WO2001046213A2 (fr) 2001-06-28
WO2001046214A2 (fr) 2001-06-28
EP1244812A1 (fr) 2002-10-02
WO2001046214A3 (fr) 2001-12-27
WO2001046213A3 (fr) 2002-05-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase