AU2023269227A1 - New indazole derivatives - Google Patents

New indazole derivatives Download PDF

Info

Publication number
AU2023269227A1
AU2023269227A1 AU2023269227A AU2023269227A AU2023269227A1 AU 2023269227 A1 AU2023269227 A1 AU 2023269227A1 AU 2023269227 A AU2023269227 A AU 2023269227A AU 2023269227 A AU2023269227 A AU 2023269227A AU 2023269227 A1 AU2023269227 A1 AU 2023269227A1
Authority
AU
Australia
Prior art keywords
compound
methyl
compound according
formula
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2023269227A
Other languages
English (en)
Inventor
Georg Jaeschke
Bruno Martoglio
Yvonne Alice Nagel
Christa Ulrike OBST-SANDER
Antonio Ricci
Sandra Steiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2023269227A1 publication Critical patent/AU2023269227A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2023269227A 2022-05-13 2023-05-11 New indazole derivatives Pending AU2023269227A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP22173211 2022-05-13
EP22173211.8 2022-05-13
EP22175324.7 2022-05-25
EP22175324 2022-05-25
PCT/EP2023/062529 WO2023217923A1 (en) 2022-05-13 2023-05-11 New indazole derivatives

Publications (1)

Publication Number Publication Date
AU2023269227A1 true AU2023269227A1 (en) 2024-10-03

Family

ID=86604076

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2023269227A Pending AU2023269227A1 (en) 2022-05-13 2023-05-11 New indazole derivatives

Country Status (10)

Country Link
US (1) US20250313565A1 (cg-RX-API-DMAC7.html)
EP (1) EP4522617A1 (cg-RX-API-DMAC7.html)
JP (1) JP2025515833A (cg-RX-API-DMAC7.html)
KR (1) KR20250012058A (cg-RX-API-DMAC7.html)
CN (1) CN119173518A (cg-RX-API-DMAC7.html)
AR (1) AR129307A1 (cg-RX-API-DMAC7.html)
AU (1) AU2023269227A1 (cg-RX-API-DMAC7.html)
CA (1) CA3256325A1 (cg-RX-API-DMAC7.html)
TW (1) TW202402276A (cg-RX-API-DMAC7.html)
WO (1) WO2023217923A1 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2961187T3 (es) 2019-06-21 2024-03-08 Hoffmann La Roche Inhibidor de EGFR para el tratamiento del cáncer
CN116507328A (zh) 2020-12-01 2023-07-28 豪夫迈·罗氏有限公司 新的吲唑衍生物
IL303064A (en) 2020-12-01 2023-07-01 Hoffmann La Roche NEW INDAZOLE ACETYLENE DERIVATIVES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2961187T3 (es) * 2019-06-21 2024-03-08 Hoffmann La Roche Inhibidor de EGFR para el tratamiento del cáncer

Also Published As

Publication number Publication date
CN119173518A (zh) 2024-12-20
KR20250012058A (ko) 2025-01-23
EP4522617A1 (en) 2025-03-19
TW202402276A (zh) 2024-01-16
JP2025515833A (ja) 2025-05-20
US20250313565A1 (en) 2025-10-09
CA3256325A1 (en) 2023-11-16
AR129307A1 (es) 2024-08-07
WO2023217923A1 (en) 2023-11-16

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