AU2023235279A1 - Engineered and chimeric nucleases - Google Patents

Engineered and chimeric nucleases Download PDF

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Publication number
AU2023235279A1
AU2023235279A1 AU2023235279A AU2023235279A AU2023235279A1 AU 2023235279 A1 AU2023235279 A1 AU 2023235279A1 AU 2023235279 A AU2023235279 A AU 2023235279A AU 2023235279 A AU2023235279 A AU 2023235279A AU 2023235279 A1 AU2023235279 A1 AU 2023235279A1
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Australia
Prior art keywords
engineered
chimeric nucleases
nucleases
chimeric
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Pending
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AU2023235279A
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Inventor
Alan Brooks
Christopher Brown
Cristina Noel BUTTERFIELD
Daniela S. A. GOLTSMAN
Jyun-Liang LIN
Isabel NOCEDAL
Morayma M. TEMOCHE-DIAZ
Brian C. THOMAS
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Metagenomi Therapeutics Inc
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Metagenomi Inc
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Publication date
Application filed by Metagenomi Inc filed Critical Metagenomi Inc
Publication of AU2023235279A1 publication Critical patent/AU2023235279A1/en
Pending legal-status Critical Current

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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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AU2023235279A 2022-03-14 2023-03-14 Engineered and chimeric nucleases Pending AU2023235279A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202263319725P 2022-03-14 2022-03-14
US63/319,725 2022-03-14
US202263335542P 2022-04-27 2022-04-27
US63/335,542 2022-04-27
US202263392814P 2022-07-27 2022-07-27
US63/392,814 2022-07-27
US202363482294P 2023-01-30 2023-01-30
US63/482,294 2023-01-30
PCT/US2023/064351 WO2023178115A2 (en) 2022-03-14 2023-03-14 Engineered and chimeric nucleases

Publications (1)

Publication Number Publication Date
AU2023235279A1 true AU2023235279A1 (en) 2024-10-03

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AU2023235279A Pending AU2023235279A1 (en) 2022-03-14 2023-03-14 Engineered and chimeric nucleases

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US (1) US20250002886A1 (https=)
EP (1) EP4493682A4 (https=)
JP (1) JP2025510622A (https=)
KR (1) KR20240158989A (https=)
CN (1) CN119095954A (https=)
AU (1) AU2023235279A1 (https=)
CA (1) CA3254301A1 (https=)
MX (1) MX2024011247A (https=)
WO (1) WO2023178115A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3225082A1 (en) * 2021-08-27 2023-03-02 Brian C. Thomas Enzymes with ruvc domains

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10913941B2 (en) * 2019-02-14 2021-02-09 Metagenomi Ip Technologies, Llc Enzymes with RuvC domains
BR112023014719A2 (pt) * 2021-01-22 2023-12-05 Metagenomi Inc Novas nucleases quiméricas e manipuladas
AU2022380842A1 (en) * 2021-11-05 2024-05-23 Metagenomi Therapeutics, Inc. Base editing enzymes

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WO2023178115A2 (en) 2023-09-21
CA3254301A1 (en) 2023-09-21
MX2024011247A (es) 2025-01-09
JP2025510622A (ja) 2025-04-15
EP4493682A2 (en) 2025-01-22
US20250002886A1 (en) 2025-01-02
KR20240158989A (ko) 2024-11-05
CN119095954A (zh) 2024-12-06
EP4493682A4 (en) 2026-04-15

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