JP2025510622A - 操作されたヌクレアーゼ及びキメラヌクレアーゼ - Google Patents

操作されたヌクレアーゼ及びキメラヌクレアーゼ Download PDF

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JP2025510622A
JP2025510622A JP2024554788A JP2024554788A JP2025510622A JP 2025510622 A JP2025510622 A JP 2025510622A JP 2024554788 A JP2024554788 A JP 2024554788A JP 2024554788 A JP2024554788 A JP 2024554788A JP 2025510622 A JP2025510622 A JP 2025510622A
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sequence
engineered
seq
nos
endonuclease
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JPWO2023178115A5 (https=
JP2025510622A5 (https=
Inventor
トーマス，ブライアン，シー．
ブルックス，アラン
ブラウン，クリストファー
バターフィールド，クリスティーナ，ノエル
ゴルツマン，ダニエラ，エス．，エー．
リン，ジュン－リアン
ノセダル，イザベル
テモチェ－ディアス，モライマ，エム．
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メタゲノミ，インク．
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Publication of JP2025510622A publication Critical patent/JP2025510622A/ja
Publication of JPWO2023178115A5 publication Critical patent/JPWO2023178115A5/ja
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
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    • C12Y306/04—Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
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JP2024554788A 2022-03-14 2023-03-14 操作されたヌクレアーゼ及びキメラヌクレアーゼ Pending JP2025510622A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202263319725P 2022-03-14 2022-03-14
US63/319,725 2022-03-14
US202263335542P 2022-04-27 2022-04-27
US63/335,542 2022-04-27
US202263392814P 2022-07-27 2022-07-27
US63/392,814 2022-07-27
US202363482294P 2023-01-30 2023-01-30
US63/482,294 2023-01-30
PCT/US2023/064351 WO2023178115A2 (en) 2022-03-14 2023-03-14 Engineered and chimeric nucleases

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Publication Number Publication Date
JP2025510622A true JP2025510622A (ja) 2025-04-15
JPWO2023178115A5 JPWO2023178115A5 (https=) 2026-03-24
JP2025510622A5 JP2025510622A5 (https=) 2026-03-24

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JP2024554788A Pending JP2025510622A (ja) 2022-03-14 2023-03-14 操作されたヌクレアーゼ及びキメラヌクレアーゼ

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US (1) US20250002886A1 (https=)
EP (1) EP4493682A4 (https=)
JP (1) JP2025510622A (https=)
KR (1) KR20240158989A (https=)
CN (1) CN119095954A (https=)
AU (1) AU2023235279A1 (https=)
CA (1) CA3254301A1 (https=)
MX (1) MX2024011247A (https=)
WO (1) WO2023178115A2 (https=)

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Publication number Priority date Publication date Assignee Title
CA3225082A1 (en) * 2021-08-27 2023-03-02 Brian C. Thomas Enzymes with ruvc domains

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10913941B2 (en) * 2019-02-14 2021-02-09 Metagenomi Ip Technologies, Llc Enzymes with RuvC domains
BR112023014719A2 (pt) * 2021-01-22 2023-12-05 Metagenomi Inc Novas nucleases quiméricas e manipuladas
AU2022380842A1 (en) * 2021-11-05 2024-05-23 Metagenomi Therapeutics, Inc. Base editing enzymes

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WO2023178115A2 (en) 2023-09-21
CA3254301A1 (en) 2023-09-21
MX2024011247A (es) 2025-01-09
EP4493682A2 (en) 2025-01-22
US20250002886A1 (en) 2025-01-02
KR20240158989A (ko) 2024-11-05
AU2023235279A1 (en) 2024-10-03
CN119095954A (zh) 2024-12-06
EP4493682A4 (en) 2026-04-15

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