AU2022405508A1 - Methods and compositions for discovery of receptor-ligand specificity by engineered cell entry - Google Patents
Methods and compositions for discovery of receptor-ligand specificity by engineered cell entry Download PDFInfo
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- AU2022405508A1 AU2022405508A1 AU2022405508A AU2022405508A AU2022405508A1 AU 2022405508 A1 AU2022405508 A1 AU 2022405508A1 AU 2022405508 A AU2022405508 A AU 2022405508A AU 2022405508 A AU2022405508 A AU 2022405508A AU 2022405508 A1 AU2022405508 A1 AU 2022405508A1
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A61K40/00—Cellular immunotherapy
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/7056—Lectin superfamily, e.g. CD23, CD72
- C07K14/70564—Selectins, e.g. CD62
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- C07K16/10—RNA viruses
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- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C12N15/1034—Isolating an individual clone by screening libraries
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- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
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- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
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- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2740/00—Reverse transcribing RNA viruses
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- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
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- C12N2740/16045—Special targeting system for viral vectors
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- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
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- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
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- Virology (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163286507P | 2021-12-06 | 2021-12-06 | |
| US63/286,507 | 2021-12-06 | ||
| US202263382860P | 2022-11-08 | 2022-11-08 | |
| US63/382,860 | 2022-11-08 | ||
| PCT/US2022/080915 WO2023107886A1 (en) | 2021-12-06 | 2022-12-05 | Methods and compositions for discovery of receptor-ligand specificity by engineered cell entry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2022405508A1 true AU2022405508A1 (en) | 2024-05-30 |
Family
ID=86731257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022405508A Pending AU2022405508A1 (en) | 2021-12-06 | 2022-12-05 | Methods and compositions for discovery of receptor-ligand specificity by engineered cell entry |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250027073A1 (https=) |
| EP (1) | EP4444878A4 (https=) |
| JP (1) | JP2024542811A (https=) |
| KR (1) | KR20240112950A (https=) |
| AU (1) | AU2022405508A1 (https=) |
| CA (1) | CA3238531A1 (https=) |
| IL (1) | IL312832A (https=) |
| WO (1) | WO2023107886A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4281569A4 (en) * | 2021-01-25 | 2025-04-02 | The Regents Of The University Of California | Methods and compositions for labeling and selecting antigen-specific T cells |
| WO2024081820A1 (en) * | 2022-10-13 | 2024-04-18 | Sana Biotechnology, Inc. | Viral particles targeting hematopoietic stem cells |
| CN121844055A (zh) * | 2023-08-16 | 2026-04-10 | 深圳市济因生物科技有限公司 | 一种病毒载体及其在感染b细胞中的应用 |
| WO2025072615A1 (en) | 2023-09-29 | 2025-04-03 | Orbital Therapeutics, Inc. | Improved methods of making rna by splinted ligation and compositions thereof |
| WO2025212851A2 (en) | 2024-04-03 | 2025-10-09 | Orbital Therapeutics, Inc. | mRNA COMPOSITIONS AND USES THEREOF IN VARICELLA ZOSTER VIRUS VACCINES |
| WO2025259931A1 (en) | 2024-06-14 | 2025-12-18 | Orbital Therapeutics, Inc. | Compositions and methods for rna circularization |
| WO2026006203A2 (en) | 2024-06-24 | 2026-01-02 | Orbital Therapeutics, Inc. | Compositions and methods for making circular rna |
| WO2026006687A1 (en) | 2024-06-28 | 2026-01-02 | Orbital Therapeutics, Inc. | Circular rna compositions and uses thereof for diseases caused by varicella-zoster virus |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7799945B2 (ja) * | 2017-09-22 | 2026-01-16 | サントル ナショナル ドゥ ラ ルシェルシュ シアンティフィック | 変異型ウイルスタンパク質 |
| US11535865B2 (en) * | 2018-02-06 | 2022-12-27 | The Broad Institute, Inc. | Co-packaging to mitigate intermolecular recombination |
| JP7658584B2 (ja) * | 2019-05-23 | 2025-04-08 | マサチューセッツ インスティテュート オブ テクノロジー | リガンドの発見およびレトロウイルス表面ディスプレーを介した遺伝子送達 |
| US12195723B2 (en) * | 2019-11-08 | 2025-01-14 | The Broad Institute, Inc. | Engineered antigen presenting cells and uses thereof |
| CN115243713A (zh) * | 2020-03-05 | 2022-10-25 | 埃克苏马生物技术公司 | 用于递送修饰的淋巴细胞聚集体的方法和组合物 |
-
2022
- 2022-12-05 CA CA3238531A patent/CA3238531A1/en active Pending
- 2022-12-05 AU AU2022405508A patent/AU2022405508A1/en active Pending
- 2022-12-05 US US18/716,869 patent/US20250027073A1/en active Pending
- 2022-12-05 JP JP2024533284A patent/JP2024542811A/ja active Pending
- 2022-12-05 EP EP22905264.2A patent/EP4444878A4/en active Pending
- 2022-12-05 WO PCT/US2022/080915 patent/WO2023107886A1/en not_active Ceased
- 2022-12-05 IL IL312832A patent/IL312832A/en unknown
- 2022-12-05 KR KR1020247022307A patent/KR20240112950A/ko active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4444878A4 (en) | 2026-04-29 |
| CA3238531A1 (en) | 2023-06-15 |
| WO2023107886A1 (en) | 2023-06-15 |
| US20250027073A1 (en) | 2025-01-23 |
| EP4444878A1 (en) | 2024-10-16 |
| IL312832A (en) | 2024-07-01 |
| KR20240112950A (ko) | 2024-07-19 |
| JP2024542811A (ja) | 2024-11-15 |
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