AU2022378590A1 - Methods for nucleic acid cleavage - Google Patents
Methods for nucleic acid cleavage Download PDFInfo
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- AU2022378590A1 AU2022378590A1 AU2022378590A AU2022378590A AU2022378590A1 AU 2022378590 A1 AU2022378590 A1 AU 2022378590A1 AU 2022378590 A AU2022378590 A AU 2022378590A AU 2022378590 A AU2022378590 A AU 2022378590A AU 2022378590 A1 AU2022378590 A1 AU 2022378590A1
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- nucleic acid
- bifunctional molecule
- binds
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- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
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- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
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- FRACPXUHUTXLCX-BELIEFIBSA-N tert-butyl N-{1-[(1S)-1-{[(1R,2S)-1-(benzylcarbamoyl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}-2-cyclopropylethyl]-2-oxopyridin-3-yl}carbamate Chemical compound CC(C)(C)OC(=O)NC1=CC=CN(C1=O)[C@@H](CC2CC2)C(=O)N[C@@H](C[C@@H]3CCNC3=O)[C@H](C(=O)NCC4=CC=CC=C4)O FRACPXUHUTXLCX-BELIEFIBSA-N 0.000 description 1
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- WBYWAXJHAXSJNI-VOTSOKGWSA-M trans-cinnamate Chemical compound [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2115540.3A GB202115540D0 (en) | 2021-10-28 | 2021-10-28 | Methods for nucleic acid cleavage |
| GB2115540.3 | 2021-10-28 | ||
| PCT/EP2022/080220 WO2023073181A2 (en) | 2021-10-28 | 2022-10-28 | Methods for nucleic acid cleavage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2022378590A1 true AU2022378590A1 (en) | 2024-05-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022378590A Pending AU2022378590A1 (en) | 2021-10-28 | 2022-10-28 | Methods for nucleic acid cleavage |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240417778A1 (https=) |
| EP (1) | EP4423295A2 (https=) |
| JP (1) | JP2024540097A (https=) |
| AU (1) | AU2022378590A1 (https=) |
| CA (1) | CA3236292A1 (https=) |
| GB (1) | GB202115540D0 (https=) |
| WO (1) | WO2023073181A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202300884D0 (en) * | 2023-01-20 | 2023-03-08 | Cambridge Entpr Ltd | Compounds for nucleic acid cleavage |
| GB202300886D0 (en) * | 2023-01-20 | 2023-03-08 | Cambridge Entpr Ltd | Compounds for nucleic acid cleavage |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022034177A1 (en) * | 2020-08-12 | 2022-02-17 | Cambridge Enterprise Limited | Method for targeted nucleic acid cleavage |
-
2021
- 2021-10-28 GB GBGB2115540.3A patent/GB202115540D0/en not_active Ceased
-
2022
- 2022-10-28 AU AU2022378590A patent/AU2022378590A1/en active Pending
- 2022-10-28 EP EP22813156.1A patent/EP4423295A2/en active Pending
- 2022-10-28 JP JP2024525379A patent/JP2024540097A/ja active Pending
- 2022-10-28 CA CA3236292A patent/CA3236292A1/en active Pending
- 2022-10-28 WO PCT/EP2022/080220 patent/WO2023073181A2/en not_active Ceased
- 2022-10-28 US US18/702,310 patent/US20240417778A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023073181A2 (en) | 2023-05-04 |
| GB202115540D0 (en) | 2021-12-15 |
| US20240417778A1 (en) | 2024-12-19 |
| WO2023073181A3 (en) | 2023-06-08 |
| JP2024540097A (ja) | 2024-10-31 |
| EP4423295A2 (en) | 2024-09-04 |
| CA3236292A1 (en) | 2023-05-04 |
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