AU2022348518A1 - Controlled lesion and immune response to pulsed electric field therapy - Google Patents

Controlled lesion and immune response to pulsed electric field therapy Download PDF

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Publication number
AU2022348518A1
AU2022348518A1 AU2022348518A AU2022348518A AU2022348518A1 AU 2022348518 A1 AU2022348518 A1 AU 2022348518A1 AU 2022348518 A AU2022348518 A AU 2022348518A AU 2022348518 A AU2022348518 A AU 2022348518A AU 2022348518 A1 AU2022348518 A1 AU 2022348518A1
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AU
Australia
Prior art keywords
energy
energy delivery
pef
electric field
tumor
Prior art date
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Pending
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AU2022348518A
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English (en)
Inventor
William S. Krimsky
Robert E. Ii Neal
Timothy J. O'brien
Chiara PASTORI
Matthew T. SILVESTRINI
Jonathan R. WALDSTREICHER
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Galvanize Therapeutics Inc
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Galvanize Therapeutics Inc
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Publication date
Application filed by Galvanize Therapeutics Inc filed Critical Galvanize Therapeutics Inc
Publication of AU2022348518A1 publication Critical patent/AU2022348518A1/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206—Generators therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Radiation-Therapy Devices (AREA)
AU2022348518A 2021-09-20 2022-09-19 Controlled lesion and immune response to pulsed electric field therapy Pending AU2022348518A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163246239P 2021-09-20 2021-09-20
US63/246,239 2021-09-20
US202163290529P 2021-12-16 2021-12-16
US63/290,529 2021-12-16
US202263322319P 2022-03-22 2022-03-22
US63/322,319 2022-03-22
US202263351562P 2022-06-13 2022-06-13
US63/351,562 2022-06-13
PCT/US2022/044021 WO2023044124A1 (en) 2021-09-20 2022-09-19 Controlled lesion and immune response to pulsed electric field therapy

Publications (1)

Publication Number Publication Date
AU2022348518A1 true AU2022348518A1 (en) 2024-04-04

Family

ID=85603549

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2022348518A Pending AU2022348518A1 (en) 2021-09-20 2022-09-19 Controlled lesion and immune response to pulsed electric field therapy

Country Status (5)

Country Link
EP (1) EP4404857A4 (cg-RX-API-DMAC7.html)
JP (1) JP2024534500A (cg-RX-API-DMAC7.html)
AU (1) AU2022348518A1 (cg-RX-API-DMAC7.html)
CA (1) CA3233052A1 (cg-RX-API-DMAC7.html)
WO (1) WO2023044124A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3474760B1 (en) 2016-06-27 2023-01-11 Galvanize Therapeutics, Inc. Generator and a catheter with an electrode for treating a lung passageway
US12564440B2 (en) 2021-04-26 2026-03-03 Pulse Biosciences, Inc. Multi-strut ablation and sensing catheter devices and methods
CA3215962A1 (en) 2021-04-26 2022-11-03 Roman Turovskiy Circumferential ablation devices and methods
US12446944B2 (en) 2021-04-26 2025-10-21 Pulse Biosciences, Inc. Mapping and ablation applicators
WO2025043024A2 (en) * 2023-08-22 2025-02-27 Galvanize Therapeutics, Inc. Quantification of immunological status and treatment planning
JP2025050034A (ja) * 2023-09-22 2025-04-04 日本ライフライン株式会社 電源装置およびアブレーションシステム
CN117982802B (zh) * 2024-04-07 2024-06-18 浙江大学 一种闭环肺部肿瘤电场治疗系统

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0810066A2 (pt) * 2007-04-19 2015-05-05 The Foundry Inc Sistemas e métodos para criação de um efeito utilizando energia de microondas à tecido específico
WO2015085162A1 (en) * 2013-12-05 2015-06-11 Rfemb Holdings, Llc Cancer immunotherapy by radiofrequency electrical membrane breakdown (rf-emb)
JP7461881B2 (ja) * 2017-12-26 2024-04-04 ガルヴァナイズ セラピューティクス，インコーポレイテッド 疾患状態および障害の治療のための方法、装置、およびシステム
DK3731771T3 (da) * 2017-12-26 2023-08-28 Galvanize Therapeutics Inc V462033dk00
US11311329B2 (en) * 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
EP3852868B1 (en) 2018-09-18 2025-02-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
CN118203401A (zh) 2019-04-18 2024-06-18 盖能适治疗股份有限公司 用于治疗异常组织的装置、系统和方法
EP3998973A4 (en) 2019-07-16 2023-07-26 Galvanize Therapeutics, Inc. TREATMENT OF THE REPRODUCTIVE TRACT WITH PULSED ELECTRIC FIELDS
EP4065005A4 (en) * 2019-11-27 2023-12-27 North Carolina State University METHOD FOR CONTROLLING TREATMENT VOLUME, HEAT GRADIENTS, MUSCLE STIMULATION AND IMMUNE RESPONSES IN PULSED ELECTRICAL FIELD TREATMENTS
WO2021127558A1 (en) 2019-12-18 2021-06-24 Galary, Inc. Treatment of cardiac tissue with pulsed electric fields
CN115348844A (zh) 2020-04-08 2022-11-15 盖能适治疗股份有限公司 脉冲电场波形操作和使用
WO2023172773A1 (en) 2022-03-11 2023-09-14 Virginia Tech Intellectual Properties, Inc. Systems and methods of using pulsed electric fields to spatially control cell death mechanisms

Also Published As

Publication number Publication date
EP4404857A4 (en) 2025-07-16
WO2023044124A1 (en) 2023-03-23
CA3233052A1 (en) 2023-03-23
JP2024534500A (ja) 2024-09-20
EP4404857A1 (en) 2024-07-31

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