AU2022296193A1 - Medicament for treatment and/or prevention of cancer - Google Patents

Medicament for treatment and/or prevention of cancer Download PDF

Info

Publication number
AU2022296193A1
AU2022296193A1 AU2022296193A AU2022296193A AU2022296193A1 AU 2022296193 A1 AU2022296193 A1 AU 2022296193A1 AU 2022296193 A AU2022296193 A AU 2022296193A AU 2022296193 A AU2022296193 A AU 2022296193A AU 2022296193 A1 AU2022296193 A1 AU 2022296193A1
Authority
AU
Australia
Prior art keywords
seq
variable region
chain variable
antibody
gln
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2022296193A
Other languages
English (en)
Inventor
Daisuke Akazawa
Fumiyoshi Okano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Publication of AU2022296193A1 publication Critical patent/AU2022296193A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AU2022296193A 2021-06-23 2022-06-22 Medicament for treatment and/or prevention of cancer Pending AU2022296193A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021103818 2021-06-23
JP2021-103818 2021-06-23
PCT/JP2022/024812 WO2022270523A1 (ja) 2021-06-23 2022-06-22 癌の治療及び/又は予防のための医薬品

Publications (1)

Publication Number Publication Date
AU2022296193A1 true AU2022296193A1 (en) 2024-01-18

Family

ID=84545727

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2022296193A Pending AU2022296193A1 (en) 2021-06-23 2022-06-22 Medicament for treatment and/or prevention of cancer

Country Status (10)

Country Link
US (1) US20240325529A1 (enrdf_load_stackoverflow)
EP (1) EP4360648A4 (enrdf_load_stackoverflow)
JP (1) JPWO2022270523A1 (enrdf_load_stackoverflow)
KR (1) KR20240024074A (enrdf_load_stackoverflow)
CN (1) CN117545508A (enrdf_load_stackoverflow)
AU (1) AU2022296193A1 (enrdf_load_stackoverflow)
BR (1) BR112023026985A2 (enrdf_load_stackoverflow)
CA (1) CA3225420A1 (enrdf_load_stackoverflow)
MX (1) MX2023014498A (enrdf_load_stackoverflow)
WO (1) WO2022270523A1 (enrdf_load_stackoverflow)

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
WO1996002576A1 (en) 1994-07-13 1996-02-01 Chugai Seiyaku Kabushiki Kaisha Reconstituted human antibody against human interleukin-8
EP2363484A3 (en) 1998-04-03 2012-04-25 Chugai Seiyaku Kabushiki Kaisha Humanized antibody against human tissue factor (TF) and process of production of the humanized antibody
JP4334141B2 (ja) 1998-04-20 2009-09-30 グリカート バイオテクノロジー アクチェンゲゼルシャフト 抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
ES2571230T3 (es) 1999-04-09 2016-05-24 Kyowa Hakko Kirin Co Ltd Procedimiento para controlar la actividad de una molécula inmunofuncional
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
AU2004204494B2 (en) 2003-01-09 2011-09-29 Macrogenics, Inc. Identification and engineering of antibodies with variant Fc regions and methods of using same
US8388955B2 (en) 2003-03-03 2013-03-05 Xencor, Inc. Fc variants
DE10359795A1 (de) 2003-12-19 2005-07-21 Bayer Technology Services Gmbh Strangverdampfervorrichtung
KR101667319B1 (ko) 2008-08-05 2016-10-18 도레이 카부시키가이샤 암의 치료 및 예방용 의약 조성물
EP2445520A4 (en) 2009-06-22 2013-03-06 Medimmune Llc MANIPULATED FC REGIONS FOR LOCAL SPECIFIC CONJUGATION
EP2480671B8 (en) 2009-09-22 2015-10-28 ProBioGen AG Process for producing molecules containing specialized glycan structures
CN102822199B (zh) 2010-02-04 2014-10-15 东丽株式会社 癌的治疗和/或预防用药物组合物
CA2788716C (en) 2010-02-04 2019-06-18 Toray Industries, Inc. Pharmaceutical composition for treating and/or preventing cancer
US8828398B2 (en) 2010-02-04 2014-09-09 Toray Industries, Inc. Pharmaceutical composition for treating and/or preventing cancer
WO2011096517A1 (ja) 2010-02-04 2011-08-11 東レ株式会社 癌の治療及び/又は予防用医薬組成物
US9115200B2 (en) 2010-02-04 2015-08-25 Toray Industries, Inc. Pharmaceutical composition for treating cancer using a monoclonal antibody having immunological reactivity with CAPRIN-1
EP2532367B1 (en) 2010-02-04 2018-08-29 Toray Industries, Inc. Pharmaceutical agent for treatment and/or prevention of cancer
JP2013528357A (ja) 2010-03-29 2013-07-11 ザイムワークス,インコーポレイテッド 強化又は抑制されたエフェクター機能を有する抗体
US9180188B2 (en) 2011-08-04 2015-11-10 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prophylaxis of cancer
EP2740796B1 (en) 2011-08-04 2017-05-17 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prophylaxis of cancer
PL2740793T3 (pl) 2011-08-04 2018-04-30 Toray Industries, Inc. Kompozycja leku do leczenia i/lub zapobiegania nowotworowi
KR102041832B1 (ko) 2011-08-04 2019-11-08 도레이 카부시키가이샤 췌장암의 치료 및/또는 예방용 의약 조성물
MX348578B (es) 2011-08-04 2017-06-20 Toray Industries Composicion farmaceutica para el tratamiento y/o prevencion de cancer.
PT2740795T (pt) 2011-08-04 2017-01-09 Toray Industries Composição de fármaco para o tratamento e/ou a prevenção de cancro
DK2818482T3 (da) 2012-02-21 2019-07-15 Toray Industries Farmaceutisk sammensætning til behandling af cancer
PL2818481T3 (pl) 2012-02-21 2020-02-28 Toray Industries, Inc. Kompozycja farmaceutyczna do leczenia i/lub zapobiegania nowotworowi złośliwemu
MX360211B (es) 2012-02-21 2018-10-24 Toray Industries Composicion farmaceutica para el tratamiento y/o prevencion del cancer.
KR102005786B1 (ko) 2012-02-21 2019-07-31 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물
CA2869120C (en) 2012-03-30 2023-05-23 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of liver cancer
AU2013241043B2 (en) 2012-03-30 2017-11-09 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of gall bladder cancer
CN112587671A (zh) 2012-07-18 2021-04-02 博笛生物科技有限公司 癌症的靶向免疫治疗
DK3031826T3 (en) 2013-08-09 2018-12-17 Toray Industries Pharmaceutical composition for the treatment and / or prevention of cancer
CN111936164B (zh) * 2018-03-30 2024-09-17 东丽株式会社 癌的治疗和/或预防用药物组合物

Also Published As

Publication number Publication date
CN117545508A (zh) 2024-02-09
BR112023026985A2 (pt) 2024-03-12
CA3225420A1 (en) 2022-12-29
EP4360648A4 (en) 2025-10-08
JPWO2022270523A1 (enrdf_load_stackoverflow) 2022-12-29
EP4360648A1 (en) 2024-05-01
WO2022270523A1 (ja) 2022-12-29
KR20240024074A (ko) 2024-02-23
US20240325529A1 (en) 2024-10-03
MX2023014498A (es) 2024-01-25

Similar Documents

Publication Publication Date Title
AU2019277138B2 (en) Multi-specific binding proteins and improvements thereon
AU2022298240A1 (en) Medicament for treatment and/or prevention of cancer
AU2017230850B2 (en) Siglec neutralizing antibodies
AU2017228474B2 (en) Antibodies to TIGIT
AU2017228055B2 (en) Antibodies specific to human poliovirus receptor (PVR)
JP7317185B2 (ja) メソテリン結合タンパク質
AU2019325036B2 (en) BCMA chimeric antigen receptor based on single domain antibody and use thereof
AU2017233658B2 (en) Cell injury inducing therapeutic drug for use in cancer therapy
AU2017384687B2 (en) Bispecific anti-TNF-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
AU2017313405B2 (en) Anti-TIGIT antibodies, anti-PVRIG antibodies and combinations thereof
AU2023274207A1 (en) FGFR2 inhibitors alone or in combination with immune stimulating agents in cancer treatment
AU2016369485B2 (en) Group B adenovirus encoding an anti-TCR-complex antibody or fragment
AU2021225827B2 (en) Humanized monoclonal antibody for 2019 novel coronavirus and use thereof
AU2020212767B2 (en) Combined pharmaceutical composition for treating tumor
AU2021291259B2 (en) Anti-Claudin18.2 antibody and use thereof
AU2020332969B2 (en) Anti-PD-L1 single domain antibodies
AU2019242559B2 (en) Monoclonal antibodies that bind to SSEA4 and uses thereof
CA2452058A1 (en) Bispecific antibodies that bind to vegf receptors
AU2004290918B2 (en) Chimeric anti CD44 antibodies and their use for treating acute myeloid leukemia
AU2020211350B2 (en) Recombinant rhabdovirus encoding for CCL21
AU2017252574B2 (en) ALK7 binding proteins and uses thereof
AU2020252119B2 (en) Interleukin-2 variants with modified biological activity
AU2021301921B2 (en) Bispecific antibody and use thereof
AU2022219332A1 (en) Anti-cd112r antibody and use thereof
AU2017276726B2 (en) Herpesvirus with modified glycoprotein D