AU2022269663A1 - Spatiotemporally resolved transcriptomics at subcellular resolution - Google Patents

Spatiotemporally resolved transcriptomics at subcellular resolution Download PDF

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Publication number
AU2022269663A1
AU2022269663A1 AU2022269663A AU2022269663A AU2022269663A1 AU 2022269663 A1 AU2022269663 A1 AU 2022269663A1 AU 2022269663 A AU2022269663 A AU 2022269663A AU 2022269663 A AU2022269663 A AU 2022269663A AU 2022269663 A1 AU2022269663 A1 AU 2022269663A1
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Prior art keywords
oligonucleotide probe
oligonucleotide
disease
complementary
barcode sequence
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AU2022269663A
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Jingyi Ren
Xiao Wang
Hu ZENG
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Massachusetts Institute of Technology
Broad Institute Inc
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Massachusetts Institute of Technology
Broad Institute Inc
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    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
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    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
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AU2022269663A 2021-05-07 2022-05-06 Spatiotemporally resolved transcriptomics at subcellular resolution Pending AU2022269663A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163185511P 2021-05-07 2021-05-07
US63/185,511 2021-05-07
US202263314873P 2022-02-28 2022-02-28
US63/314,873 2022-02-28
PCT/US2022/028012 WO2022236011A1 (en) 2021-05-07 2022-05-06 Spatiotemporally resolved transcriptomics at subcellular resolution

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Publication Number Publication Date
AU2022269663A1 true AU2022269663A1 (en) 2023-11-23

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AU2022269663A Pending AU2022269663A1 (en) 2021-05-07 2022-05-06 Spatiotemporally resolved transcriptomics at subcellular resolution

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US (1) US20240254545A1 (https=)
EP (1) EP4334471A1 (https=)
JP (1) JP2024518437A (https=)
KR (1) KR20240005872A (https=)
AU (1) AU2022269663A1 (https=)
CA (1) CA3218089A1 (https=)
IL (1) IL308267A (https=)
WO (1) WO2022236011A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7502787B2 (ja) 2018-04-09 2024-06-19 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー インサイチュ遺伝子配列決定の方法
US12467081B2 (en) 2020-11-23 2025-11-11 Pleno, Inc. Encoded endonuclease assays
WO2022246242A1 (en) * 2021-05-21 2022-11-24 The Board Of Trustees Of The Leland Stanford Junior University Scalable distributed processing software for next-generation in situ sequencing
WO2024167929A1 (en) * 2023-02-06 2024-08-15 Applied Materials, Inc. Target probes with landmark sequences for localizing gene transcripts by fluorescence in situ hybridization
WO2025059443A1 (en) 2023-09-15 2025-03-20 The Broad Institute, Inc. Untargeted multiplexed in situ rna profiling and the uses and means therefor
WO2025136916A1 (en) 2023-12-18 2025-06-26 The Board Institute, Inc. Thick tissue transcriptomics and translatomics
WO2025189030A1 (en) 2024-03-07 2025-09-12 Stellaromics, Inc. Methods and systems for volumetric imaging
JP7758403B1 (ja) * 2025-02-03 2025-10-22 バイオ － セラピー、フィジオロジカル システムズ フォー ヘルス ソシエタ ペル アチオニ 天然マトリックスに基づく治療用の製品又は有益な製品の生理学的活性を、定性定量的にベネフィット／リスクについて評価するための、合成分子に基礎を置く薬理学的活性又は栄養補助活性を有する他の製品が有するものと対比による、新しい好適な方法

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US10434197B2 (en) 2010-07-23 2019-10-08 University Of Delaware Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes
JP7502787B2 (ja) 2018-04-09 2024-06-19 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー インサイチュ遺伝子配列決定の方法

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IL308267A (en) 2024-01-01
WO2022236011A1 (en) 2022-11-10
CA3218089A1 (en) 2022-11-10
KR20240005872A (ko) 2024-01-12
JP2024518437A (ja) 2024-05-01
US20240254545A1 (en) 2024-08-01
EP4334471A1 (en) 2024-03-13

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