AU2022232759A1 - Stabilized liquid compositions comprising a levodopa-tyrosine conjugate and uses thereof - Google Patents

Stabilized liquid compositions comprising a levodopa-tyrosine conjugate and uses thereof Download PDF

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Publication number
AU2022232759A1
AU2022232759A1 AU2022232759A AU2022232759A AU2022232759A1 AU 2022232759 A1 AU2022232759 A1 AU 2022232759A1 AU 2022232759 A AU2022232759 A AU 2022232759A AU 2022232759 A AU2022232759 A AU 2022232759A AU 2022232759 A1 AU2022232759 A1 AU 2022232759A1
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Australia
Prior art keywords
pharmaceutical composition
liquid pharmaceutical
amino
composition according
acid
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AU2022232759A
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Inventor
Mazzi Dagan-Lion
Elana Gazal
Avital Laxer
Alex MAINFIELD
Kenji Morokuma
Akira Nakao
Kazuki Nakayama
Alaa TALHAMI
Irena VAINSHTOK
Eiji Yoshida
Eduardo Zawoznik
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Neuroderm Ltd
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Neuroderm Ltd
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Publication of AU2022232759A1 publication Critical patent/AU2022232759A1/en
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    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
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    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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