AU2021366975A1 - Novel CXCR4-targeting compounds - Google Patents
Novel CXCR4-targeting compounds Download PDFInfo
- Publication number
- AU2021366975A1 AU2021366975A1 AU2021366975A AU2021366975A AU2021366975A1 AU 2021366975 A1 AU2021366975 A1 AU 2021366975A1 AU 2021366975 A AU2021366975 A AU 2021366975A AU 2021366975 A AU2021366975 A AU 2021366975A AU 2021366975 A1 AU2021366975 A1 AU 2021366975A1
- Authority
- AU
- Australia
- Prior art keywords
- residue
- lys
- forms
- ipr
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063094839P | 2020-10-21 | 2020-10-21 | |
| US63/094,839 | 2020-10-21 | ||
| PCT/CA2021/051486 WO2022082312A1 (en) | 2020-10-21 | 2021-10-21 | Novel cxcr4-targeting compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2021366975A1 true AU2021366975A1 (en) | 2023-04-13 |
Family
ID=81291055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021366975A Pending AU2021366975A1 (en) | 2020-10-21 | 2021-10-21 | Novel CXCR4-targeting compounds |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240100203A1 (https=) |
| EP (1) | EP4232459A4 (https=) |
| JP (1) | JP2023549469A (https=) |
| KR (1) | KR20230092906A (https=) |
| CN (1) | CN116457028A (https=) |
| AU (1) | AU2021366975A1 (https=) |
| CA (1) | CA3194483A1 (https=) |
| IL (1) | IL301342A (https=) |
| WO (1) | WO2022082312A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4511384A1 (en) * | 2022-04-20 | 2025-02-26 | Provincial Health Services Authority | Cxcr4-targeting compounds, and methods of making and using the same |
| US12614326B2 (en) * | 2023-05-03 | 2026-04-28 | GE Precision Healthcare LLC | Methods and systems for scatter and tailing correction |
| US12514939B2 (en) | 2024-02-14 | 2026-01-06 | Alpha-9 Oncology, Inc. | Stable radiopharmaceutical compositions and uses thereof |
| WO2025171492A1 (en) * | 2024-02-14 | 2025-08-21 | Alpha-9 Oncology Inc. | Stable radiopharmaceutical compositions and uses thereof |
| WO2025218761A1 (zh) * | 2024-04-17 | 2025-10-23 | 晶核生物医药科技(上海)有限公司 | 环状肽类化合物、其药物组合物及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006035705A1 (de) * | 2006-08-01 | 2008-02-07 | Robert Bosch Gmbh | Kolben einer Fahrzeugbremsanlagen-Kolbenpumpe |
| EP2377579A1 (en) * | 2007-05-30 | 2011-10-19 | Eli Lilly and Company | Cyclic peptide CXCR4 antagonists |
| CN113150068B (zh) * | 2017-09-20 | 2023-04-04 | 尚华医药科技(江西)有限公司 | 一种肽类化合物、其应用及含其的组合物 |
| JP2021165234A (ja) * | 2018-07-03 | 2021-10-14 | 富士フイルム富山化学株式会社 | Ｃｘｃｒ４結合性化合物もしくはその塩またはそれらと金属との錯体 |
| US20220218852A1 (en) * | 2019-04-18 | 2022-07-14 | Provincial Health Services Authority | Novel radiolabelled cxcr4-targeting compounds for diagnosis and therapy |
-
2021
- 2021-10-21 JP JP2023524397A patent/JP2023549469A/ja active Pending
- 2021-10-21 AU AU2021366975A patent/AU2021366975A1/en active Pending
- 2021-10-21 IL IL301342A patent/IL301342A/en unknown
- 2021-10-21 CN CN202180071425.XA patent/CN116457028A/zh active Pending
- 2021-10-21 WO PCT/CA2021/051486 patent/WO2022082312A1/en not_active Ceased
- 2021-10-21 CA CA3194483A patent/CA3194483A1/en active Pending
- 2021-10-21 EP EP21881418.4A patent/EP4232459A4/en active Pending
- 2021-10-21 KR KR1020237013276A patent/KR20230092906A/ko active Pending
- 2021-10-21 US US18/032,680 patent/US20240100203A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20240342321A1 (en) | 2024-10-17 |
| US20240100203A1 (en) | 2024-03-28 |
| EP4232459A4 (en) | 2024-12-04 |
| KR20230092906A (ko) | 2023-06-26 |
| JP2023549469A (ja) | 2023-11-27 |
| CN116457028A (zh) | 2023-07-18 |
| EP4232459A1 (en) | 2023-08-30 |
| WO2022082312A1 (en) | 2022-04-28 |
| IL301342A (en) | 2023-05-01 |
| CA3194483A1 (en) | 2022-04-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11395857B2 (en) | Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy | |
| WO2022082312A1 (en) | Novel cxcr4-targeting compounds | |
| EP3986872A1 (en) | Radiolabeled compounds targeting the prostate-specific membrane antigen | |
| JP7541532B2 (ja) | 診断及び治療のための新規な放射性標識されたｃｘｃｒ４を標的とする化合物 | |
| US12472272B2 (en) | Radiolabelled compounds for diagnosis or treatment of prostate-specific membrane antigen- expressing cancer | |
| US20250242064A1 (en) | Cxcr4-targeting compounds, and methods of making and using the same | |
| US20250195702A1 (en) | Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (grpr) and treatment of grpr-related disorders | |
| US12616761B2 (en) | CXCR4-targeting compounds | |
| WO2025054727A1 (en) | Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (grpr) and treatment of grpr-related disorders | |
| WO2026055788A1 (en) | Gastrin-releasing peptide receptor (grpr)-targeted compounds and uses thereof | |
| WO2025111712A1 (en) | Gastrin-releasing peptide receptor (grpr)-targeted compounds and uses thereof |