AU2021343534A1 - TREATMENT OF NF-κB-MEDIATED DISEASE - Google Patents

TREATMENT OF NF-κB-MEDIATED DISEASE Download PDF

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Publication number
AU2021343534A1
AU2021343534A1 AU2021343534A AU2021343534A AU2021343534A1 AU 2021343534 A1 AU2021343534 A1 AU 2021343534A1 AU 2021343534 A AU2021343534 A AU 2021343534A AU 2021343534 A AU2021343534 A AU 2021343534A AU 2021343534 A1 AU2021343534 A1 AU 2021343534A1
Authority
AU
Australia
Prior art keywords
human patient
day
vamorolone
muscular dystrophy
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2021343534A
Other languages
English (en)
Other versions
AU2021343534A9 (en
Inventor
Jesse DAMSKER
Eric Hoffman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reveragen Biopharma Inc
Original Assignee
Reveragen Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reveragen Biopharma Inc filed Critical Reveragen Biopharma Inc
Publication of AU2021343534A1 publication Critical patent/AU2021343534A1/en
Publication of AU2021343534A9 publication Critical patent/AU2021343534A9/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AU2021343534A 2020-09-21 2021-09-21 TREATMENT OF NF-κB-MEDIATED DISEASE Pending AU2021343534A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063081073P 2020-09-21 2020-09-21
US63/081,073 2020-09-21
US202163195473P 2021-06-01 2021-06-01
US63/195,473 2021-06-01
US202163214908P 2021-06-25 2021-06-25
US63/214,908 2021-06-25
PCT/US2021/051274 WO2022061287A1 (en) 2020-09-21 2021-09-21 TREATMENT OF NF-κB-MEDIATED DISEASE

Publications (2)

Publication Number Publication Date
AU2021343534A1 true AU2021343534A1 (en) 2023-05-11
AU2021343534A9 AU2021343534A9 (en) 2024-10-17

Family

ID=80776432

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2021343534A Pending AU2021343534A1 (en) 2020-09-21 2021-09-21 TREATMENT OF NF-κB-MEDIATED DISEASE

Country Status (9)

Country Link
US (2) US20220184098A1 (https=)
EP (1) EP4213855A4 (https=)
JP (1) JP2023543439A (https=)
KR (1) KR20230092905A (https=)
AU (1) AU2021343534A1 (https=)
CA (1) CA3170698A1 (https=)
IL (1) IL301500A (https=)
MX (1) MX2023003258A (https=)
WO (1) WO2022061287A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4436583A4 (en) * 2021-11-22 2025-04-02 ReveraGen BioPharma, Inc. TREATMENT OF NF-kB-MEDIATED DISEASE
WO2025199347A1 (en) * 2024-03-21 2025-09-25 Reveragen Biopharma, Inc. Treatment of glomerulonephritis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006279325B2 (en) * 2005-08-18 2013-06-27 Accelalox, Inc. Methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway
CA2855756A1 (en) * 2011-11-29 2013-06-06 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of nf-kb for treatment of disease
WO2014205045A1 (en) * 2013-06-18 2014-12-24 Downes, Michael Methods of treating muscular dystrophy
PL4023222T3 (pl) * 2015-09-08 2025-03-24 The Children's Hospital Of Philadelphia Nieselektywny aktywator metabotropowych receptorów glutaminianu do leczenia zespołu 22q
US11382922B2 (en) * 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Also Published As

Publication number Publication date
WO2022061287A1 (en) 2022-03-24
JP2023543439A (ja) 2023-10-16
KR20230092905A (ko) 2023-06-26
US20220184098A1 (en) 2022-06-16
CA3170698A1 (en) 2022-03-24
MX2023003258A (es) 2023-05-08
IL301500A (en) 2023-05-01
EP4213855A4 (en) 2024-10-23
EP4213855A1 (en) 2023-07-26
US20240139210A1 (en) 2024-05-02

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