AU2021252542A1 - Reusable initiators for synthesizing nucleic acids - Google Patents

Reusable initiators for synthesizing nucleic acids Download PDF

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Publication number
AU2021252542A1
AU2021252542A1 AU2021252542A AU2021252542A AU2021252542A1 AU 2021252542 A1 AU2021252542 A1 AU 2021252542A1 AU 2021252542 A AU2021252542 A AU 2021252542A AU 2021252542 A AU2021252542 A AU 2021252542A AU 2021252542 A1 AU2021252542 A1 AU 2021252542A1
Authority
AU
Australia
Prior art keywords
modified
nucleotide
group
exo
deoxyguanosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2021252542A
Other languages
English (en)
Inventor
Sanjay Agarwalla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Assemblies Inc
Original Assignee
Molecular Assemblies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/841,214 external-priority patent/US11384377B2/en
Application filed by Molecular Assemblies Inc filed Critical Molecular Assemblies Inc
Publication of AU2021252542A1 publication Critical patent/AU2021252542A1/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2021252542A 2020-04-06 2021-04-06 Reusable initiators for synthesizing nucleic acids Pending AU2021252542A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/841,214 2020-04-06
US16/841,214 US11384377B2 (en) 2013-04-02 2020-04-06 Reusable initiators for synthesizing nucleic acids
PCT/US2021/025918 WO2021207158A1 (en) 2020-04-06 2021-04-06 Reusable initiators for synthesizing nucleic acids

Publications (1)

Publication Number Publication Date
AU2021252542A1 true AU2021252542A1 (en) 2022-11-10

Family

ID=78023444

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2021252542A Pending AU2021252542A1 (en) 2020-04-06 2021-04-06 Reusable initiators for synthesizing nucleic acids

Country Status (6)

Country Link
EP (1) EP4133070A1 (de)
JP (1) JP2023521704A (de)
CN (1) CN116096882A (de)
AU (1) AU2021252542A1 (de)
CA (1) CA3179701A1 (de)
WO (1) WO2021207158A1 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5872244A (en) * 1994-09-02 1999-02-16 Andrew C. Hiatt 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds
US8808989B1 (en) * 2013-04-02 2014-08-19 Molecular Assemblies, Inc. Methods and apparatus for synthesizing nucleic acids

Also Published As

Publication number Publication date
WO2021207158A1 (en) 2021-10-14
CN116096882A (zh) 2023-05-09
CA3179701A1 (en) 2021-10-14
JP2023521704A (ja) 2023-05-25
EP4133070A1 (de) 2023-02-15

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