AU2020102519A4 - Feed additive with the effect of promoting lactation and improving meat quality - Google Patents
Feed additive with the effect of promoting lactation and improving meat quality Download PDFInfo
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- AU2020102519A4 AU2020102519A4 AU2020102519A AU2020102519A AU2020102519A4 AU 2020102519 A4 AU2020102519 A4 AU 2020102519A4 AU 2020102519 A AU2020102519 A AU 2020102519A AU 2020102519 A AU2020102519 A AU 2020102519A AU 2020102519 A4 AU2020102519 A4 AU 2020102519A4
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- 239000003674 animal food additive Substances 0.000 title claims abstract description 33
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- 239000003814 drug Substances 0.000 claims abstract description 16
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- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 2
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- LTINPJMVDKPJJI-UHFFFAOYSA-N iodinated glycerol Chemical compound CC(I)C1OCC(CO)O1 LTINPJMVDKPJJI-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/254—Acanthopanax or Eleutherococcus
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Fodder In General (AREA)
Abstract
The invention discloses a plant feed additive, which is characterized by comprising the
following main drugs in parts by weight: 2-10 parts of Radix Astragali seu Hedysari, 10-35
parts of Semen Vaccariae, 5-15 parts of Fructus Liquidambaris, 10-40 parts of Herba Taraxaci,
1-10 parts of Radix Glycyrrhizae, 5-20 parts of Medulla Tetrapanacis, 3-8 parts of Cortex
Acanthopanax Radicis and/or leaf, 5-12 parts of Radix Angelicae Sinensis, 5-25 parts of Radix
Paeoniae Alba and 2-15 Angelica decursiva. The plant feed additive is applied to the feeding
of the postpartum mammals or the growing-period mammals and has the functions of
promoting the lactation and improving the meat quality.
Description
Feed additive with the effect of promoting lactation and improving meat quality
[0001] The invention relates to the field of feed additive, in particular, to a plant feed additive with the effect of promoting lactation and improving meat quality. The invention also relates to the preparation method and use of the additive.
[0002] With the increase of the world's population and the improvement of people's living standards and quality of life, the demand for meat in daily life is increasing, green health food is more and more favored by the market, The previous feeding mode of one-sided pursuit of promoting growth, preventing disease, more milk producing, rapid effect and aggressive use of antibiotics with large side effects is no longer suitable for the market demand. It is worth popularizing the new feeding mode that use uses natural plants and other new feed additives to comprehensively regulate the meat quality of livestock, improve the animal's own metabolic function, enhance the body's immunity and have no side effects.
[0003] CN1739375A discloses a Chinese herbal milk promoter for dairy cows. Its formula is divided into three parts: main drug, auxiliary drug and carrier, the ingredients of main drug are: Semen Vaccariae 100g, Fructus Liquidambaris 50g, Medulla Tetrapanacis 25g, Akebia quinata 25g, Rhizoma Ligustici Chuanxiong 50g, Herba Taraxaci 50g. Using Chinese herbal medicine that stimulate the menstrual flow and promote lactation as the main drugs, such as Semen Vaccariae, and Fructus Liquidambaris etc., and Chinese herbal medicine that detoxifying and activating blood circulation as the auxiliary drugs, such as Rhizoma Ligustici Chuanxiong and Herba Taraxaci etc., which constitute the Chinese medicinal herbal lactogenic additive, can
improve the individual yield level of dairy cows and reduce the occurrence of recessive mastitis.
[0004] CN1O1181011A discloses a Chinese herbal medicine feed additive-Xia-an powder and its preparation and application. The additive is made of raw materials with the following weight ratio: Radix Astragali seu Hedysari 10-30g, Radix Angelica
Sinensis 10-30g, Radix Ophiopogon 5-20g, ericarpium Citri Reticulatae 5-20g, Pericarpium Citri Reticulatae Viride 5-20g, Retinervus Luffae Fructus 5-20g, Herba Taraxaci 15-35g, Fructus Forsythiae 10-30g, Radix Bupleuri 5-20g, Flos Lonicerae rattan 15-35g, Fructus Trichosanthis 10-30g, Semen Vaccariae 5-20g, Fructus Liquidambaris 5-20g, Radix Glycyrrhizae 3-10g. The present additive has anti-heat stress effect on lactating cows, thereby increasing milk yield, and can significantly reduce the incidence of mastitis, endometritis, and hoof disease.
[0005] CN102526175A discloses a Chinese herbal medicine composition for the preventing and treating dairy-free syndrome of livestock, in which the proportion of the components of the Chinese herbal medicine composition and their parts by weight is: -20 parts of Semen Vaccariae; 10-20 parts of Radix Astragali seu Hedysari; 5-10 parts of Spina Gleditsiae; 5-10 parts of Radix Angelicae Sinensis; 10-20 parts of Radix Codonopsis; 10-20 parts of Rhizoma Ligustici Chuanxiong; 5-10 parts of Radix Glycyrrhiza; 5-10 parts of Fructus Liquidambaris; 10-15 parts of Akebia quinata; 10 parts of Herba Taraxaci. The composition has the function of enriching the blood, clearing heat and promoting diuresis, pus draining and toxin expelling, activating blood circulation and removing blood stasis, and dredging collateral for promoting lactation, with the capable of effectively improve the immunity and milk yield of dairy cows and other livestock.
[0006] At present, in terms of plant feed additives, a fewinventions have been used to promote maternal lactation, improve milk yield, and have effects of anti-inflammatory or to boost immunity, but there are few species. At the same time, the existing plant feed additives, there is less research or attention to the lactation with additive on the mother and baby's growth, but also less research but also less research about this kind of additives used in maternal animals and growing animals for meat tenderness, flavor, color, such as hydraulic impact on meat quality, lack of lactation and improve meat quality effect of additives.
[0007] The purpose of the present invention is to provide a plant feed additive with green, healthy, natural lactation effect whileimproving animal meat quality to address the above-mentioned shortcomings in the background art.
[0008] Another purpose of the present invention is to provide a preparation method and use of the feed additive.
[0009] The technical problems solved by the present invention are realized by the following technical schemes:
[0010] The invention provides a plant feed additive with the effect of promoting lactation and improving meat quality, which is characterized by comprising the following main drugs in parts by weight: 2-10 parts of Radix Astragali seu Hedysari, -35 parts of Semen Vaccariae, 5-15 parts of Fructus Liquidambaris, 10-40 parts of Herba Taraxaci, 1-10 parts of Radix Glycyrrhizae, 5-20 parts of Medulla Tetrapanacis, 3-8 parts of Cortex Acanthopanax Radicis and/or leaf, 5-12 parts of Radix Angelicae Sinensis, 5-25 parts of Radix Paeoniae Alba and 2-15 Angelica decursiva.
[0011] Preferably, the above-mentioned plant feed additive is characterized by comprising the following main drugs in parts by weight: 4 parts of Radix Astragali seu Hedysari, 22 parts of Semen Vaccariae, 8 parts of Fructus Liquidambaris, 25 parts of Herba Taraxaci, 1 parts of Radix Glycyrrhizae, 10 parts of Medulla Tetrapanacis, 5 parts of Cortex Acanthopanax Radicis and/or leaf, 8 parts of Radix Angelicae Sinensis, 12 parts of Radix Paeoniae Alba and 5 parts of Angelica decursiva.
[0012] The invention also relates to the application of the above-mentioned plant feed additive in the preparation of a feed additive for feeding postpartum mammals or growing mammals.
[0013] In particular, the application of the above-mentioned plant feed additives in the preparation of plant feed additives with the effect of promoting lactation and improving meat quality.
[0014] Among them, the mammals are mainly pigs, cow and sheep.
[0015] The above-mentioned plant feed additive of the present invention may also contain auxiliary materialsselected from one or more kinds of wheat bran, rice bran, dextrin, starch and sub-powder.
[0016] The invention also provides a method for the above-mentioned plant feed additive, which is characterized by comprising the following steps:
[0017] (1) Radix Astragali seu Hedysari, Semen Vaccariae, Fructus Liquidambaris, Herba Taraxaci, Radix Glycyrrhizae and Medulla Tetrapanacis are extracted with water to obtain water extraction;
[0018] (2) Cortex Acanthopanax Radicis and/or leaf, Radix Angelicae Sinensis, Radix Paeoniae Alba and Angelica decursiva are extracted with alcohol to obtain alcohol extract.
[0019] (3) The resulting water extract and alcohol extract are mixed, dried and crushed.
[0020] Preferably, the method described above is characterized by:
[0021] (1), Radix Astragali seu Hedysari is extracted according to the proportion, with water flash extraction for 3 times, 3min each time, and the extract was collected,
reduced pressure and concentrated to the thick paste, and microwave vacuum drying was performed to obtain the astragalus extraction.
[0022] (2), Semen Vaccariae, Fructus Liquidambaris, Herba Taraxaci, Radix Glycyrrhizae and Medulla Tetrapanacis are extracted according to the proportion, which crushed into coarse powder, respectively or mixed and then extracted with water twice, the extract was collected, sprayed and dried to obtain the dry paste of water extraction;
[0023] (3), Cortex Acanthopanax Radicis and/or leaf, Radix Angelicae Sinensis, Radix Paeoniae Alba and Angelica decursiva are extracted according to the proportion, which crushed into coarse powder, heated reflux and extracted for 3 times after respectively or mixed and then soaked with 95% ethanol, decompression recovered the ethanol, and the extract collected, sprayed and dried to obtain the dry paste of alcohol extraction;
[0024] (4), The resulting extract and dry paste from (1), (2), (3) crushed, mixed evenly, passed through 80 mesh sieve, inspected to be qualified and divided into packaging to obtain the finished product.
[0025] The method described above in the invention may also be:
[0026] (1) Radix Astragali seu Hedysari, Semen Vaccariae, Fructus Liquidambaris, Herba Taraxaci and Radix Glycyrrhizae are extracted according to the proportion, which crushed into coarse powder, respectively or mixed and then extracted with water for 1-3 times, to collect the extract solution;
[0027] (2), Cortex Acanthopanax Radicis and/or leaf, Radix Angelicae Sinensis, Radix Paeoniae Alba and Angelica decursiva are extracted according to the proportion, which crushed into coarse powder, respectively or mixed and then soaked with 95% ethanol for 1-3 times, decompression recovered the ethanol to collect the extract solution;
[0028] (3), The extract solution from (1) and (2) is mixed, decompressed, concentrated, dried and dried to obtain a dry paste;
[0029] (4), Dry paste is crushed, mixed evenly, passed through 80 mesh sieve, inspected to be qualified and divided into packaging to obtain the finished product.
[0030] Also, the method for producing the plant feed additive above-mentioned in the invention is characterized in that the it's obtained after medicinal material is directly crushed and mixed.
[0031] The flash extraction adopted by the invention is a known technology in the field of traditional Chinese medicine extraction, which relies on high-speed mechanical
shear force and hyperkinetic molecular filtration technology to break the plant material into fine particles within a few seconds at room temperature and in the presence of solvents for several seconds, and the make effective components quickly reach to prevent internal and external balance, and achieve the purpose of extraction through filtration. The extraction method can retain the effective components of the plants to the maximum extent without damaged by heat and has the advantages of normal temperature extraction, less solvent consumption, short extraction time, high efficiency and simple operation steps etc.
[0032] According to farm breeding experiments and research, the plant feed additive of invention is prepared from 0.1% -% of the ration ratio and added to the feed after being prepared with raw materials, or directly fed at this ratio or drunk after dissolving with water, can achieve the expected effect.
[0033] The advantages of the plant feed additive of the invention are mainly manifested in: it is used for postpartum maternal feeding, has a good lactation effect and accelerates the postpartum recovery, as well as breastfeeding pups for disease resistance and growth promotion; it can be used in the growing period of animals to be fully coordinated animal body function, significantly increase the feed conversion rate and growth rate, improve the immune function, reduce and prevent the occurrence of disease, increase the lean meat rate, reduce water loss rate, increase the meat tand improve the meat quality.And the product has simple process, raw materials come from nature, no pollution, no residue, no side effects such as drug resistance.
[0034] In order to make the technical means, creative features, purpose and efficacy of the invention easy to be understood, the present invention is further explained by the following specific embodiments.
[0035] Embodiment 1
[0036] Weigh the raw materials (Kg) according to the following weight ratio:
[0037] Radix Astragali seu Hedysari 4, Semen Vaccariae 22, Fructus Liquidambaris 8
[0038] Herba Taraxaci 25, Radix Glycyrrhizae 1, Medulla Tetrapanacis 10
[0039] Cortex Acanthopanax Radicis 5, Radix Angelicae Sinensis 8, Radix Paeoniae Alba 12
[0040] Angelica decursiva 5
[0041] The preparation method is:
[0042] (a), Radix Astragali seu Hedysari (4Kg) is extracted according to the proportion, with water flash extraction for 3 times, 3min each time, and the extract was collected, reduced pressure and concentrated to the thick paste, and microwave vacuum drying was performed to obtain the astragalus extract.
[0043] (b), Semen Vaccariae 22Kg, Fructus Liquidambaris 8Kg, Herba Taraxaci 8Kg Radix Glycyrrhizae 1Kg and Medulla Tetrapanacis 10Kg are extracted according to the proportion, which crushed into coarse powder, mixed and then extracted with water twice under 90-100°C, 2h each time, the extract was collected, sprayed and dried to obtain the dry paste of water extraction;
[0044] (c), Cortex Acanthopanax Radicis (Root, stem and leaf) 5Kg, Radix Angelicae Sinensis 8Kg, Radix Paeoniae Alba 12Kg and Angelica decursiva 5Kg are extracted according to the proportion, which crushed into coarse powder, heated reflux and extracted for 3 times (1.5h each time) after mixed and then soaked with 95% ethanol for 2 days, decompression recovered the ethanol, and the extract collected, sprayed and dried to obtain the dry paste of alcohol extraction;
[0045] (d), The resulting extraction and dry paste from a, b, c are crushed, mixed evenly, passed through 80 mesh sieve, inspected to be qualified and divided into packaging to obtain the finished product.
[0046] Embodiment 2
[0047] Weigh the raw materials (Kg) according to the following weight ratios:
[0048] Radix Astragali seu Hedysari 10, Semen Vaccariae 14, Fructus Liquidambaris
[0049] Herba Taraxaci 15, Radix Glycyrrhizae 2, Medulla Tetrapanacis 15
[0050] Cortex Acanthopanax Radicis 5, Radix Angelicae Sinensis 10, Radix Paeoniae Alba 14
[0051] Angelica decursiva 6
[0052] The preparation method is:
[0053] (1), Radix Astragali seu Hedysari is extracted according to the proportion, with water flash extraction for 3 times, 3min each time, and the extract was collected,
reduced pressure and concentrated to the thick paste, and microwave vacuum drying was performed to obtain the astragalus extraction;
[0054] (2), Semen Vaccariae, Fructus Liquidambaris, Herba Taraxaci, Radix Glycyrrhizae and Medulla Tetrapanacis are extracted according to the proportion, which crushed into coarse powder, respectively or mixed and then extracted with water for twice, the extract was collected, sprayed and dried to obtain the dry paste of water extraction;
[0055] (3), Cortex Acanthopanax Radicis and/or leaf, Radix Angelicae Sinensis, Radix Paeoniae Alba and Angelica decursiva are extracted according to the proportion, which crushed into coarse powder, heated reflux and extracted for 3 times after respectively or mixed and then soaked with 95% ethanol, decompression recovered the ethanol, and the extract collected, sprayed and dried to obtain the dry paste of alcohol extraction;
[0056] (4), The resulting extract and dry paste from (1), (2), (3) crushed, mixed evenly, passed through 80 mesh sieve, inspected to be qualified and divided into packaging to obtain the finished product.
[0057] Embodiment 3
[0058] Weigh the raw materials (Kg) according to the following weight ratio:
[0059] Radix Astragali seu Hedysari 8, Semen Vaccariae 20, Fructus Liquidambaris 12
[0060] Herba Taraxaci 10, Radix Glycyrrhizae 2, Medulla Tetrapanacis 14
[0061] Cortex Acanthopanax Radicis 8, Radix Angelicae Sinensis 7, Radix Paeoniae Alba 11
[0062] Angelica decursiva 9
[0063] The preparation method is:
[0064] (1), Radix Astragali seu Hedysari, Semen Vaccariae, Fructus Liquidambaris, Herba Taraxaci and Radix Glycyrrhizae are extracted according to the proportion, which crushed into coarse powder, respectively or mixed and then extracted with water for 1-3 times, to collect the extract solution;
[0065] (2), Cortex Acanthopanax Radicis (root or stem) and/or leaf, Radix Angelicae Sinensis, Radix Paeoniae Alba and Angelica decursiva are extracted according to the proportion, which crushed into coarse powder, extracted for 1-3 times after respectively or mixed and then soaked with 95% ethanol, decompression recovered the ethanol, and the extract collected, sprayed and dried to collect the extract solution;
[0066] (3), The resulting extracts in (1) and (2) are mixed, concentrated under reduced pressure and dried to obtain a dry paste.
[0067] (4), Dry paste is crushed, mixed evenly, passed through 80 mesh sieve, inspected to be qualified and divided into packaging to obtain the finished product.
[0068] The beneficial effects of the present invention are illustrated by clinical animal experiments and standardized farm feeding, in particular, comprising the beneficial effects of the present invention in promoting lactation, improving nutrient digestibility and immune response of sows, promoting growth of fattening pigs and improving meat quality, etc.
[0069] Experimental Example 1: Effects on Nutrient Digestibility and Immune Response of Sows
[0070] In order to verify the beneficial effect of the invention on lactation of sows and weight gain of piglets, the experimental example was used to research the nutrient digestion and immune regulation of the present invention for sows, and its effect was compared with the background CN102526175A.
[0071] 1 Materials and Methods
[0072] 1 Experimental material
[0073] Feed used in the experiment is purchased from the market; all medicinal materials purchased from the medicinal materials market in Bozhou, Anhui province and tested in accordance with the Pharmacopoeia Standard of the 2010 Edition. The patent is produced according to embodiment 1, and samples are obtained. The patent CN102526175A with lactation effect in the background technology is used as the control group, and is prepared according to the data stated in the patent.
[0074] 2 Experimental Animals and Groups
[0075] The sows (Landrace xYorkshire) were divided into 3 groups, each group repeated 20 times for 60 animals in total. The experimental feed given 7 days before delivery and the feed test carried out from delivery to weaning.
[0076] Experimental design: (1), normal control group CON (basic diet), (2), experimental group HE 1 (basic diet +0.2% additivein the embodiment 1 of the present invention) and (3), experimental group HE2 (basic diet +0.2% the additive described in CN102526175A), 10 piglets assigned to each repeated sow after delivery.
[0077] 3 Experimental Feed and Feeding Management
[0078] The feed is based on com-soybean meal, which is given twice in the morning and evening according to the feeding program of lactating sows, with free intake of water.
[0079] 4 Detection Indicators and Methods
[0080] (1) Weight gain, survival rate and diarrhea index of piglets
[0081] For weight gain, weight measured at the beginning (delivery) and at the end (weaning) respectively, and the result calculated; survival rate, the total number of piglets confirmed at the beginning (daily) for calculation; diarrhoea index, measured on the 3rd, 6th, 9th and 12th day from the start of the trial, and also week after weaning.
[0082] (2) Rectal temperature, waist back, and estrus after weaning of lactating sow
[0083] With regard to the thickness of waist back of mammals, at the beginning (delivery) and at the end (weaning); for all sows, the back fat meter used to measure the distance of 5cm from the 1 and 10 ribs and the 3 parts of the lumbar spine, and the average value of the 3 measured values taken; for rectal temperature, at the beginning (delivery) and end (weaning), determined by a rectal thermometer. And the days of final weaning solstice feeding counted as oestrus after weaning.
[0084] (3) Contents of related hormones in the blood of lactating sows
[0085] The content of related hormones in the blood of lactating sows collected with blood vessels from the beginning of delivery to the end of weaning, centrifuged at 2 mL and 4 °C for 15 minutes at 3000 rpm. The resulting serum used to measure the contents of cortisol, epinephrine and norepinephrine with an automatic biochemical analyzer.
[0086] (4) Dry matter content in feces of lactating sows
[0087] For all sows, feces should be collected with anal massage before feeding, 0, 10 and 20 days after delivery. The collected feces should be dried at 80 °C for 72 hours and calculated by the dry matter content calculation method the feces.
[0088] (5) Nutrient digestibility of lactating sows
[0089] In order to determine the digestibility of nutrients, feces taken at the end, and 0.2% marked substance Cr203 added to the feed 5 days ago before collecting feces, and the feces dried at 60 °C for 72 hours, crushed and used for analysis. The mixed Cr of general composition and the marked substance analyzed according to the AOAC method.
[0090] 5 Statistical Analysis
[0091] Using the general linear model of SAS of data, dealt with a new multiple range to detect the mean difference.
[0092] 2 Results and Discussion
[0093] 1. Production performance
[0094] When the additive is added to the feed, the effect on the performance of the suckling piglets is shown in Table 1. For the weaning weight and daily weight gain, the addition group is significantly higher than the normal control group (P <0.05), the present invention group and the existing patent group had significant improvements in the rate of daily weight gain, survival rate and recuperation rate There is no significant difference in the initial weight, survival rate and diarrhea index (P> 0.05), and the incidence of diarrhea in the piglets using the invention reduced.
[0095] Table 1 Effects of Chinese medicine feed additive on growth performance and antidiarrheal effect of suckling piglets
Item CON HEl HE2 SE
Initial weight 1.35 1.39 1.43 0.06
Weaning 6.36 7.40 7.31 0.22 weight
Daily gain 239 286 280 10
Survival rate 92.96 96.65 95.83 3.23
5.75 3.00 3.25 2.14 Incidence of diarrhea
[0097] 2 Other indicators
[0098] The feed added with the present invention and the disclosed CN102526175A lactation feed additive has no significant difference in rectal temperature, waist thickness and estrus after weaning, blood biochemical index and moisture content in feces of lactating sows, and the dry matter, nitrogen and energy digestibility increased in the additive group of the present invention.
[0099] The results of this experiment show that the invention has the function of promoting lactation and improving feed efficiency, and the effect is obviously reflected in the daily weight gain and nutrient digestibility of piglets, and also has the effect of immunomodulation, which can improve the survival rate of piglets and reduce the diarrhea rate.
[0100] Experimental example 2 Effects on Growth Capacity and Meat Quality of Fattened Pig
[0101] In this experiment, the invention is used in the daily feeding of fattening pigs, and compared with the invention which has been disclosed to improve the meat quality, so as to investigate the beneficial effect of the invention in promoting the growth of fattening pigs and improving the meat quality, etc.
[0102] 1 Materials and Methods
[0103] 1 Experimental animals and design
[0104] 80 fattening pigs of 3-element hybrid [(Landrace X Yorkshire) X Duroc] as experimental animals, the average weight at the beginning of the experiment is 62.34± 1.96 kg. Treated as (1) control group (CON, basic diet), (2) experimental group HI (basic diet +0.1% additive of Example 3 of the present invention), (3) experimental group H2 (basic diet +0.2%additive of Example 3 of the present invention) and (4) H3
(basic diet +0.5% CN101664105B, 2012.05.30), a total of 4 groups, each group repeated 5 times, each repeated for 4 pigs.
[0105] 2 Determination of indicators and methods
[0106] (1) Production Performance
[0107] Weight and feed intake measured at the beginning, 5 weeks and end (10 weeks) respectively of the experiment, and daily weight gain, daily feed intake and feed efficiency calculated.
[0108] (2) Nutrient digestibility
[0109] In order to determine the digestibility of nutrients, the marked Cr203 added at the 5th week and 4 days before the end of the experiment. (10 weeks) at 0.2% of the feed. After 4 days of giving Cr feed, the feces collected and dried by hot air at 60 °C for 72 hours and crushed for analysis. The Cr mixed with the general ingredients of the feed and the marks analyzed according to the method shown in the AOAC standard.
[0110] (3) Biochemical indexes of blood
[0111] Serum biochemistry test: 10 pigs selected randomly from each group. At the 5th week and at the end (10 weeks), 5ml blood collected from the jugular vein and centrifuged at 2000g at 4°C for 30 minutes. The chemical analyzer separated, and the separated serum tested with reagents according to enzyme colorimetry, total cholesterol concentration and total cholesterol. It is measured with an automatic biochemical analyzer after the reaction of HDL cholesterol concentration with HDL-C test reagent, and neutral lipid concentration with TG test reagent.
[0112] (4) Determination of back fat thickness
[0113] Back fat thickness was measured 3 times at P2 using a back fat meter.
[0114] (5) Meat quality features
[0115] For pork after meat quality analysis, 8 pigs selected randomly from each treatment group and stored in a refrigerator at 4°C for 24 hours after slaughter, the longissimus dorsi used for analysis; for the drip loss, the sample shaped with a thickness of 2 cm and placed in a polyethylene bag, refrigerated at 4°C for 7 days, and the reduction measured. For cooking loss, the sample cut into a certain shape and weighed, placed in a polyethylene bag, heat in a constant temperature water tank at 75 0 C for 30 minutes, and cooled at room temperature for 30 minutes, weigh the sample to determine the cooking loss; for the pH of the meat, measured after slaughter using a pH meter in the middle of the back; the flesh color determined by chromatic aberration meter, and the samples determined repeatedly; sensory examination performed by 10 sensory inspectors, to determine fresh meat color (1-5), muscle fat (1-5), and hardness (1-5) based on the American Pork Association standards. The eye muscle area measured by a planimeter. The water content calculated by the surface measuring device, and the surface area of the meat divided by the moisture area to obtain the value.
[0116] 3 Statistical Analysis
[0117] All the data analyzed according to the general linear model of SAS. When there is a difference, the difference of the average of each group (P <0.05) verified by verified by the new multiple range method.
[0118] 2 Results and Discussion
[0119] 1 Production performance
[0120] When adding traditional Chinese medicines to fattening pig feed, the effect on production performance is shown in Table 2 below. Thereis no significant difference in daily weight gain, daily feed intake and feed efficiency between 0 and 5 weeks (P> 0.05); at 5-10 weeks, there is no significant difference in daily weight gain (P> 0.05), but in terms of daily feed intake, the CON group is significantly higher than the H2 and H3 group (P <0.05), and the feed efficiency of H2 group is significantly higher than that of CON group (P <0.05). During the entire test period, there is no significant difference in daily weight gain (P> 0.05). As for daily feed intake, CON group is significantly higher than H2 group (P <0.05) and for feed efficiency, the H2 group is significantly higher than CON group (P <0.05).
[0121] Table 2 Effects of specific Chinese medicinal preparations added to feed on performance of fattening pigs
Item CON HI H2 H3 SE 0to5 weeks Daily gain 849 863 866 857 22 Daily 2129 2075 1981 2110 97 intake Feed 0.399 0.416 0.437 0.406 0.02 efficiency 0.9 0 to 5 weeks Daily gain 892 926 912 910 13
2825 2772 2701 2724 27 intake Feed 0.316 0.334 0.338 0.334 0.006 efficiency Whole course Daily gain 871 895 889 884 10 Daily 2477 2424 2341 2417 39 intake Feed 0.352 0.369 0.380 0.366 0.005 efficiency
[0123] 2 Nutrient digestibility
[0124] The effects on nutrient digestibility when specific Chinese medicine preparations added to fattening pig feed as shown in table 3. At week 5, there is no significant difference in digestibility between dry matter and nitrogen (P <0.05), but in energy digestibility, H2 group is significantly higher than H3 group (P> 0.05). At week , there is no significant difference in dry matter, nitrogen and energy digestibility (P <0.05).
[0125] Table 3 Effect of specific Chinese medicinal preparations added to feed on nutrient efficiency of fattening pigs
[0126]
CON HI H2 H3 SE 5 weeks
Dry matter 76.94 77.50 77.25 76.69 0.39 Nitrogen 76.48 77.06 77.30 76.65 0.41 Energy 75.99 76.61 77.42 74.74 0.67 10 weeks
[0127]
Dry matter 75.37 75.46 75.90 75.26 0.98 Nitrogen 75.60 76.28 76.70 75.08 0.46 Energy 75.55 76.74 76.82 75.49 0.58
[0128] 3 Blood biochemical indexes
[0129] The effects of specific Chinese medicine on the blood biochemical index when adding specific Chinese medicine to the fattening pig feed as shown in table 4. At the th week, there is no significant difference in the contents of total cholesterol, HDL cholesterol and triglyceride in the blood between the groups (P> 0.05). At the 10th week, there is no significantly different in HDL-cholesterol and triglyceride content between the groups, but in the aspect of total cholesterol, HI group is lower than H3 group and CON group (P <0.05), and in the aspect of LDL-cholesterol group, the HI and H2 group are significantly lower than CON group (P <0.05).
[0130] Table 4 Effect of adding specific Chinese herbal medicine in feed on blood biochemical indexes of fattening pigs
[0131]
CON HI H2 H3 SE 5 weeks
choletrol 91.50 88.25 86.50 92.00 2.73
High density 31.68 34.08 35.55 32.15 1.83 cholesterol Low density 59.90 49.50 49.88 58.08 4.60 cholesterol Triglyceride 35.35 34.43 34.70 41.15 3.90 10 weeks
Total 108.25 99.50 97.62 107.50 1.87 cholesterol High density 48.38 50.60 50.43 50.70 1.23 cholesterol Low density 63.63 52.05 51.95 61.15 1.42 cholesterol Triglyceride 48.83 48.90 45.45 50.43 3.80
[0132] 4 Backfat Thickness
[0133] The effect of adding specific Chinese medicines in the feed of fattening pig feed on back fat thickness as shown in Table 5. There is no significant difference in back fat thickness between groups during the entire test period (P> 0.05).
[0134] Table 5 Effects of specific Chinese herbal preparations added to feed on the thickness of back fat of fattening pigs
[0135]
CON HI H2 H3 SE Initial 11.27 11.12 11.50 11.10 0.34 thickness 5 weeks 12.86 12.00 12.25 12.50 0.30 10 weeks 14.71 14.41 14.40 14.64 0.15
[0136] Meat quality features
[0137] The effect of adding specific Chinese medicine in the feed of fattening pigs on meat quality as shown in Table 6. For meat quality, sensory examination, cooking loss, dripping loss, moisture content, pH and meat color, the additive group has a significantly improvement, and the Hi group and H2 group are significantly higher than the CON group in eye muscle area (P <0.05).
[0138] Table 6 Effects of specific Chinese herbal preparations added to feed on the quality of fattening pork
[0139]
CON HI H2 H3 SE
Sensory evaluation Color 2.19 2.25 2.29 2.13 0.14 Grain 2.19 2.25 2.29 2.13 0.12 Tenacity 2.00 2.19 2.19 2.13 0.14 Cooking loss 28.44 28.16 28.13 28.79 0.52 Drip loss 1 day 4.50 4.37 4.38 4.53 0.10 2 days 8.55 8.14 8.13 8.52 0.16 3 days 11.75 11.10 11.25 11.57 0.18 Water retention 55.89 56.09 56.96 55.02 0.87 capacity pH 5.88 5.80 5.83 5.87 0.025 Flesh color Luminance 57.44 57.63 57.46 57.17 0.62 Red 17.71 17.84 17.80 17.72 0.33 Yellow 8.20 8.12 8.14 8.16 0.31 Ocular 49.79 52.14 52.68 50.17 0.67 muscle area
[0140] The experimental results show that the invention can increase daily weight gain, reduce feed intake, improve feed efficiency, improve nutrient digestibility, reduce cholesterol and improve pork quality when used for the growth of fattening pigs. Only a small amount (0.1%) can be added to make obvious improvements, greatly reduce breeding costs, improve feed efficiency, and increase economic benefits.
[0141] The above embodiments show and describe the basic principles and main characteristics of the present invention and the advantages of the present invention. Those skilled in the art shall understand that the present invention is not limited by the aforementioned embodiments, that the foregoing embodiments and instructions describe only the principles of the present invention, and that the scope of the present invention is not limited in any way, and that the present invention will be subject to changes and improvements which fall within the scope of the requirements for protection without being outside the scope of the present invention.
[0142] Although the invention has been described with reference to specific examples, it will be appreciated by those skilled in the art that the invention may be embodied in many other forms, in keeping with the broad principles and the spirit of the invention described herein.
[0143] The present invention and the described embodiments specifically include the best method known to the applicant of performing the invention. The present invention and the described preferred embodiments specifically include at least one feature that is industrially applicable
Claims (11)
1. A plant feed additive with the effect of promoting lactation and improving meat quality, which is characterized by comprising the following main drugs in parts
by weight: 2-10 parts of Radix Astragali seu Hedysari, 10-35 parts of Semen Vaccariae, -15 parts of Fructus Liquidambaris, 10-40 parts of Herba Taraxaci, 1-10 parts of Radix Glycyrrhizae, 5-20 parts of Medulla Tetrapanacis, 3-8 parts of Cortex Acanthopanax Radicis and/or leaf, 5-12 parts of Radix Angelicae Sinensis, 5-25 parts of Radix Paeoniae Alba and 2-15 Angelica decursiva.
2. The plant feed additive according to claim 1, which is characterized by comprising the following main drugs in parts by weight: 4 parts of Radix Astragali seu Hedysari, 22 parts of Semen Vaccariae, 8 parts of Fructus Liquidambaris, 25 parts of Herba Taraxaci, 1 parts of Radix Glycyrrhizae, 10 parts of Medulla Tetrapanacis, 5 parts of Cortex Acanthopanax Radicis and/or leaf, 8 parts of Radix Angelicae Sinensis, 12 parts of Radix Paeoniae Alba and 5 parts of Angelica decursiva.
3. Application of the plant feed additive according to claim 1 or 2 in the preparation of a feed additive for feeding postpartum mammals or growing mammals.
4. Application of the plant feed additive according toclaim 1 or 2 in the preparation of a plant feed additive having the effect of promoting lactation andimproving the meat quality of mammals.
5. The application according to claim 3, in which the mammal is a pig, cow or sheep.
6. The application according to claim 4, in which the mammal is a pig, cow or sheep.
7. The plant feed additive according to claim 1 or 2, which is characterized in that also contain auxiliary materialsselected from one or more kinds of wheat bran, rice bran, dextrin, starch and sub-powder.
8. A method for producing plant feed additives according to claim 1 or 2, which is characterized in that it includes the following steps:
(1) Radix Astragali seu Hedysari, Semen Vaccariae, Fructus Liquidambaris, Herba Taraxaci, Radix Glycyrrhizae and Medulla Tetrapanacis are extracted with water to obtain water extraction;
(2) Cortex Acanthopanax Radicis, Radix Angelicae Sinensis, Radix Paeoniae Alba and Angelica decursiva extracted with ethanol to make the alcohol extract solution;
(3) Mixing, drying and crushing the water extract and alcohol extract prepared above.
9. The method according to claim 8, which is characterized by:
(1) Radix Astragali seu Hedysari is extracted according to the proportion, with water flash extraction for 3 times, 3min each time, and the extract was
collected, reduced pressure and concentrated to the thick paste, and microwave vacuum drying was performed to obtain the astragalus extraction;
(2) Semen Vaccariae, Fructus Liquidambaris, Herba Taraxaci, Radix Glycyrrhizae and Medulla Tetrapanacis are extracted according to the proportion, which crushed into coarse powder, respectively or mixed and then extracted with water for twice, the extract was collected, sprayed and dried to obtain the dry paste of water extraction;
(3) Cortex Acanthopanax Radicis, Radix Angelicae Sinensis, Radix Paeoniae Alba and Angelica decursiva are extracted according to the proportion, which crushed into coarse powder, heated reflux and extracted for 3 times after respectively or mixed and then soaked with 95% ethanol, decompression recovered the ethanol, and the extract collected , sprayed and dried to obtain the dry paste of alcohol extraction;
(4) The resulting extract and dry paste from (1), (2), (3) crushed, mixed evenly, passed through 80 mesh sieve, inspected to be qualified and divided into packaging to obtain the finished product.
10. The method according to claim 8, which is characterized by:
(1) Radix Astragali seu Hedysari, Semen Vaccariae, Fructus Liquidambaris, Herba Taraxaci and Radix Glycyrrhizae are extracted according to the proportion, which crushed into coarse powder, respectively or mixed and then extracted with water for 1-3 times, to collect the extract solution;
(2) Cortex Acanthopanax Radicis, Radix Angelicae Sinensis, Radix Paeoniae Alba and Angelica decursiva are extracted according to the proportion, which crushed into coarse powder, extracted for 1-3 times after respectively or mixed and then soaked with 95% ethanol, decompression recovered the ethanol, and the extract solution collected;
(3) The resulting extracts in (1) and (2) are mixed, concentrated under reduced pressure and dried to obtain a dry paste;
(4) The dry paste is crushed and mixed evenly, passed through 80 mesh sieve, inspected to be qualified and divided into packaging to obtain the finished product.
11. A method of producing the plant feed additive described in claim 1 or 2, which characterized in that the medicinal material is obtained by directly crushed and mixed.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN111357880A (en) * | 2020-04-14 | 2020-07-03 | 中国科学院东北地理与农业生态研究所 | Additive for improving pork quality of fattening pigs |
CN113068768A (en) * | 2021-05-15 | 2021-07-06 | 内蒙古恒光大药业股份有限公司 | Feed raw material capable of improving taste of feed, improving immunity and promoting growth |
CN113854407A (en) * | 2021-09-30 | 2021-12-31 | 长沙博海生物科技有限公司 | Anti-stress feed additive for livestock and preparation method thereof |
CN113951378A (en) * | 2021-10-14 | 2022-01-21 | 中国农业科学院农业资源与农业区划研究所 | Chinese herbal medicine feeding straw particles with lactation promoting effect |
CN114304051A (en) * | 2021-11-13 | 2022-04-12 | 黑龙江省庆隆农业高科技综合推广有限公司 | Green organic chicken raising method |
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2020
- 2020-09-30 AU AU2020102519A patent/AU2020102519A4/en active Active
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111357880A (en) * | 2020-04-14 | 2020-07-03 | 中国科学院东北地理与农业生态研究所 | Additive for improving pork quality of fattening pigs |
CN113068768A (en) * | 2021-05-15 | 2021-07-06 | 内蒙古恒光大药业股份有限公司 | Feed raw material capable of improving taste of feed, improving immunity and promoting growth |
CN113854407A (en) * | 2021-09-30 | 2021-12-31 | 长沙博海生物科技有限公司 | Anti-stress feed additive for livestock and preparation method thereof |
CN113854407B (en) * | 2021-09-30 | 2024-04-12 | 长沙博海生物科技有限公司 | Feed additive for resisting stress of livestock and preparation method thereof |
CN113951378A (en) * | 2021-10-14 | 2022-01-21 | 中国农业科学院农业资源与农业区划研究所 | Chinese herbal medicine feeding straw particles with lactation promoting effect |
CN114304051A (en) * | 2021-11-13 | 2022-04-12 | 黑龙江省庆隆农业高科技综合推广有限公司 | Green organic chicken raising method |
CN114304051B (en) * | 2021-11-13 | 2024-01-26 | 黑龙江省庆隆农业高科技综合推广有限公司 | Green organic chicken raising method |
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