AU2020102397A4 - The medical and edible compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases - Google Patents
The medical and edible compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases Download PDFInfo
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- AU2020102397A4 AU2020102397A4 AU2020102397A AU2020102397A AU2020102397A4 AU 2020102397 A4 AU2020102397 A4 AU 2020102397A4 AU 2020102397 A AU2020102397 A AU 2020102397A AU 2020102397 A AU2020102397 A AU 2020102397A AU 2020102397 A4 AU2020102397 A4 AU 2020102397A4
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- AU
- Australia
- Prior art keywords
- fish oil
- preventing
- squalene
- soft capsule
- capsule
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
The invention relates to a soft capsule for preventing and treating cardiovascular and
cerebrovascular diseases, in particular to a compound squalene fish oil soft capsule. The
medical and edible compound squalene fish oil soft capsule for preventing and treating
cardiovascular and cerebrovascular diseases is comprised by capsule material and effective
component, the capsule material is gelatin and the latter is constituted by fish Oil and
squalene that are mixed by the mass percentage of 3:1. The soft capsule described in this
invention has an obvious effect on treating and preventing cardiovascular and
cerebrovascular diseases
Description
PATENTS ACT 1990
The medical and edible compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases
The invention is described in the following statement:-
The medical and edible compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases
The invention relates to a soft capsule for preventing and treating cardiovascular and cerebrovascular diseases, in particular to a compound squalene fish oil soft capsule.
With the substantial improvement of living standards, people have increased the intake of high-fat meat products, well-exceeding the required level. Therefore, the blood fat of one's body is so much increased that it causes various cardiovascular and cerebrovascular diseases that have become the number one killer of human's health. There are drugs for preventing and treating cardiovascular and cerebrovascular diseases in the current market, but the therapeutic effect is poor.
Fish oil is the general name of all oil substances in fish, including body oil, liver oil and brain oil. Main fish oil is a kind of oil extracted from fatty fish, which is rich in o-3 polyunsaturated fatty acids (DHA and EPA), and has health benefits such as anti inflammation and regulating blood lipid. In a broad sense, fish oil not only refers to fish oil preparations in the form of capsules, but also refers to the fat in fish. The main functional component is o-3 polyunsaturated fatty acids.
Squalene is a kind of lipid unsaponifiable matter, which has the following effects: 1. Protecting liver, and promoting liver cell regeneration and protecting liver cells, thus improving liver function. 2. Anti-fatigue, enhancing the body's disease resistance and improve the body's immune function. 3. Protecting adrenocortical function and improving the stress ability of the body.
4. A remarkable effect of anti-tumor, especially after cancer resection surgery or during radiotherapy and chemotherapy therapy, and its biggest feature is to prevent cancer from transferring to the lungs. 5. Raise the function of white blood cells. In view of this, the present invention has been proposed.
The technical problem to be solved by the invention lies in overcoming the defects of the prior art and providing a soft capsule that can be used as both medicine and food for preventing and treating cardiovascular and cerebrovascular diseases and has good effect.
In order to solve the above technical problems, the basic idea of the technical scheme adopted by the invention is an effective component for preventing and treating cardiovascular and cerebrovascular diseases with both medicine and food is prepared by mixing fish oil and squalene according to the mass percentage of 3:1.
A compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases is composed of capsule material and effective components, wherein the capsule material is gelatin, and the effective components are as described above. The soft capsule is prepared in a clean area above 100,000 grade according to the following method:
(1) Batching; Weighing fish oil and squalene according to the above ratio, mixing, stirring evenly, and vacuumizing to 0.08MPa;
(2) Preparing glue solution; The ingredients obtained in the step (1) are thrown into a glue melting pot, heated it to 70-80°C, stirring it for 30 minutes, and making it melt into a uniform glue solution, holding the temperature for more than 1 hour, and vacuumizing to 0.08MPa: ;
(3) Preparing capsule materials; Gelatin is formed into rubber under the rotation of a rubber wheel, and the rubber enters a rolling die to form a capsule material;
(4) Making pills; Injecting the feed liquid into the prepared capsule material to form capsules;
(5) Cleaning and disinfecting the plastic pills; After the capsules come out, drying them naturally for 24 48 hours, and cleaning the capsules with ethanol of 95% in volume
and Cleaning that capsule with alcohol, and sterilizing with ethanol of 75% in volume;
(6) Drying the capsules; Drying the cleaned and disinfected capsules for 2 hours at 22 ~ 26°C and relative humidity less than 40%.
Further, the viscosity of the glue solution in the step (2) is 2.8-3.2 degrees. Furthermore, in the step (2), the gelatinizing pot is preheated in advance. Furthermore, in the step (4), the feed liquid is injected into the capsule material through a feed pump. Furthermore, the squalene is extracted from plants.
Furthermore, the fish oil is deep sea fish oil.
Furthermore, the deep-sea fish oil is any one of tuna oil, cod oil and shark oil or a mixture of two or more of them in any proportion.
After adopting the technical scheme, the soft capsule has the following beneficial effects comparing with the prior art: the soft capsule has obvious effects on treating and preventing cardiovascular and cerebrovascular diseases.
In the following, the present invention will be further explained with specific examples to help understand the contents of the present invention.
Embodiment 1
A compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases is prepared from fish oil and squalene according to the mass percentage of 3:1 in a clean area above 100,000 according to the following method:
(1) Batching; Weighing tuna fish oil and squalene according to the above ratio, mixing, stirring evenly, and vacuumizing to 0.08MPa;
(2) Preparing glue solution; The ingredients obtained in the step (1) are thrown into a glue melting pot, heated it to 70-80°C, stirring it for 30 minutes, and making it melt into a uniform glue solution, holding the temperature for more than 2 hours, and vacuumizing to 0.08MPa; ;
(3) Preparing capsule materials; Gelatin is formed into rubber under the rotation of a rubber wheel, and the rubber enters a rolling die to form a capsule material;
(4) Making pills; Injecting the feed liquid into the prepared capsule material to form capsules;
(5) Cleaning and disinfecting the plastic pills; After the capsules come out, drying them naturally for 24~ 48 hours, and cleaning the capsules with ethanol of 95% involume
and Cleaning that capsule with alcohol, and sterilizing with ethanol of 75% in volume;
(6) Drying the capsules; Drying the cleaned and disinfected capsules for 2 hours at 22 °C and relative humidity of 30%.
The soft capsules prepared by the method described in this embodiment are administrated
To groups of hypertensive patient, for those aged 55-60 years old are assembled in a group of 50 people; For those aged 61-65 years old are assembled in a group of 50 people; For those aged 66-70 years old are assembled a group of 50 people; administrating patients with one pill three times a day for two weeks and observing them for one month without taking medicine. It is found that the patients with hypertension have different degrees of remission, among which the patients aged 55-60 years recover better and the remission rate reaches 97%. The age of 61-65 years old, the stability rate reached 94%; The age of 66-70 years old, the stability rate reached 90%.
Embodiment 2
It is basically the same as Example 1, except that the viscosity of glue solution is 3.2 degrees; Fish oil is a mixture of tuna oil and cod oil at a ratio of 1:1 In the same way, the product described in this example was given to the same hypertensive subjects as in Example 1, three times a day, one capsule each time.
After taking the medicine continuously for two weeks and observing for one month without taking the medicine, it was found that the patients with hypertension had different degrees of remission, among which the patients aged 55-60 years recovered better and the remission rate reached 95%. The age of 61-65 years old, the stability rate reached 93%; The age of 66-70 years old, the stability rate reached 90%.
The product described in this example was given to the same hyperlipidemic subjects as in Example 1, three times a day, one capsule each time. After taking the medicine continuously for two weeks and observing for one month without taking the medicine, it was found that the condition of hyperlipidemic patients decreased to varying degrees, among which the patients aged 35-40 years recovered better, and the rate of decreasing and maintaining stability reached 96%. For those aged 41-45 years, the rate of reducing and maintaining stability reached 92%; The age of 46-50 years old, the stability rate reached 91%.
The above is only the preferred embodiment of the present invention, and it should be pointed out that for ordinary people in the technical field, without departing from the principle of the present invention, several improvements and embellishments can be made, and these improvements and embellishments should also be regarded as the protection scope of the present invention.
Claims (8)
1. A compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases, which is characterized by comprising effective components prepared from fish oil and squalene according to the mass ratio of 3:1.
2. A compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases, which is characterized by comprising capsule materials and effective components, wherein the capsule materials are gelatin, and the effective components are as described in claim 1. The soft capsule is prepared in a clean area above 100,000 grade according to the following method:
(7) Batching; Weighing fish oil and squalene according to the above ratio, mixing, stirring evenly, and vacuumizing to 0.08MPa;
(8) Preparing glue solution; The ingredients obtained in the step (1) are thrown into a glue melting pot, heated it to 70-80°C, stirring it for 30 minutes, and making it melt into a uniform glue solution, holding the temperature for more than 1 hour, and vacuumizing to 0.08MPa; ;
(9) Preparing capsule materials; Gelatin is formed into rubber under the rotation of a rubber wheel, and the rubber enters a rolling die to form a capsule material;
(10) Making pills; Injecting the feed liquid into the prepared capsule material to form capsules;
(11) Cleaning and disinfecting the plastic pills; After the capsules come out, drying them naturally for 24~ 48 hours, and cleaning the capsules with ethanol of 95% involume
and Cleaning that capsule with alcohol, and sterilizing with ethanol of 75% in volume;
(12) Drying the capsules; Drying the cleaned and disinfected capsules for 2 hours at 22 ~ 26°C and relative humidity less than 40%.
3. The compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases as claimed in claim 1 is characterized in that the viscosity of the glue solution in step (2) is 2.8-3.2 degrees.
4. The compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases as claimed in claim 1 is characterized in that the gelatinizing pot in step (2) is preheated in advance.
5. A compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases as claimed in claim 1 is characterized in that the feed liquid in step (4) is injected into the capsule material through a feed pump.
6. A compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases as claimed in claim 1 is characterized in that squalene is extracted from plants.
7. A compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases as claimed in claim 1 is characterized in that the fish oil is deep sea fish oil.
8. A compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases as claimed in claim 7 is characterized in that the deep sea fish oil is any one of tuna oil, cod oil and shark oil, or a mixture of more than two in any proportion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2020102397A AU2020102397A4 (en) | 2020-09-23 | 2020-09-23 | The medical and edible compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2020102397A AU2020102397A4 (en) | 2020-09-23 | 2020-09-23 | The medical and edible compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2020102397A4 true AU2020102397A4 (en) | 2020-11-05 |
Family
ID=73016670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020102397A Active AU2020102397A4 (en) | 2020-09-23 | 2020-09-23 | The medical and edible compound squalene fish oil soft capsule for preventing and treating cardiovascular and cerebrovascular diseases |
Country Status (1)
| Country | Link |
|---|---|
| AU (1) | AU2020102397A4 (en) |
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2020
- 2020-09-23 AU AU2020102397A patent/AU2020102397A4/en active Active
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| FGI | Letters patent sealed or granted (innovation patent) |