AU2019410060A1 - Cancer treatment using docetaxel by controlling peak plasma levels - Google Patents

Cancer treatment using docetaxel by controlling peak plasma levels Download PDF

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Publication number
AU2019410060A1
AU2019410060A1 AU2019410060A AU2019410060A AU2019410060A1 AU 2019410060 A1 AU2019410060 A1 AU 2019410060A1 AU 2019410060 A AU2019410060 A AU 2019410060A AU 2019410060 A AU2019410060 A AU 2019410060A AU 2019410060 A1 AU2019410060 A1 AU 2019410060A1
Authority
AU
Australia
Prior art keywords
docetaxel
cancer
plasma levels
treatment
side effects
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2019410060A
Other languages
English (en)
Inventor
Jacob Hendrik Beijnen
Johannes Henricus Matthias Schellens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Modra Pharmaceuticals BV
Original Assignee
Modra Pharmaceuticals BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Modra Pharmaceuticals BV filed Critical Modra Pharmaceuticals BV
Publication of AU2019410060A1 publication Critical patent/AU2019410060A1/en
Priority to AU2023204682A priority Critical patent/AU2023204682A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2019410060A 2018-12-21 2019-12-18 Cancer treatment using docetaxel by controlling peak plasma levels Abandoned AU2019410060A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023204682A AU2023204682A1 (en) 2018-12-21 2023-07-14 Cancer treatment using docetaxel by controlling peak plasma levels

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18215472 2018-12-21
EP18215472.4 2018-12-21
PCT/EP2019/086124 WO2020127606A1 (en) 2018-12-21 2019-12-18 Cancer treatment using docetaxel by controlling peak plasma levels

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2023204682A Division AU2023204682A1 (en) 2018-12-21 2023-07-14 Cancer treatment using docetaxel by controlling peak plasma levels

Publications (1)

Publication Number Publication Date
AU2019410060A1 true AU2019410060A1 (en) 2021-08-05

Family

ID=64901394

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2019410060A Abandoned AU2019410060A1 (en) 2018-12-21 2019-12-18 Cancer treatment using docetaxel by controlling peak plasma levels
AU2023204682A Abandoned AU2023204682A1 (en) 2018-12-21 2023-07-14 Cancer treatment using docetaxel by controlling peak plasma levels

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2023204682A Abandoned AU2023204682A1 (en) 2018-12-21 2023-07-14 Cancer treatment using docetaxel by controlling peak plasma levels

Country Status (14)

Country Link
US (3) US20220079910A1 (https=)
EP (2) EP3897610B1 (https=)
JP (3) JP2022515249A (https=)
KR (1) KR20220002860A (https=)
CN (1) CN113543781A (https=)
AU (2) AU2019410060A1 (https=)
BR (1) BR112021012255A2 (https=)
CA (1) CA3124316C (https=)
CL (1) CL2021001638A1 (https=)
ES (1) ES3026709T3 (https=)
IL (1) IL284213A (https=)
MX (2) MX2021007478A (https=)
PE (1) PE20220250A1 (https=)
WO (1) WO2020127606A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020127607A1 (en) * 2018-12-21 2020-06-25 Modra Pharmaceuticals B.V. Combination treatment for solid tumors using docetaxel and a cyp3a inhibitor
PE20220250A1 (es) * 2018-12-21 2022-02-16 Modra Pharmaceuticals B V Uso de docetaxel en el tratamiento de cancer mediante control de niveles maximos en plasma
GB202201935D0 (en) 2022-02-14 2022-03-30 Modra Pharmaceuticals B V Methods and compositions for treating cancer in taxane-resistant patients

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR054215A1 (es) 2006-01-20 2007-06-13 Eriochem Sa Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit
US9089544B2 (en) * 2007-08-24 2015-07-28 Slotervaart Participaties Bv Composition
GB0716591D0 (en) * 2007-08-24 2007-10-03 Vereniging Het Nl Kanker I Composition
MX2010002179A (es) * 2007-08-24 2010-04-27 Stichting Het Nl Kanker I Composicion para el tratamiento de enfermedades neoplasicas.
JP2012500788A (ja) 2008-08-22 2012-01-12 スティヒティング ヘット ネーデルランド カンケル インスティテュート 組成物
WO2020127607A1 (en) * 2018-12-21 2020-06-25 Modra Pharmaceuticals B.V. Combination treatment for solid tumors using docetaxel and a cyp3a inhibitor
PE20220250A1 (es) * 2018-12-21 2022-02-16 Modra Pharmaceuticals B V Uso de docetaxel en el tratamiento de cancer mediante control de niveles maximos en plasma

Also Published As

Publication number Publication date
EP4670718A2 (en) 2025-12-31
CA3124316A1 (en) 2020-06-25
JP2022515249A (ja) 2022-02-17
BR112021012255A2 (pt) 2021-09-28
CL2021001638A1 (es) 2022-04-22
IL284213A (en) 2021-08-31
JP2023102787A (ja) 2023-07-25
MX2025008270A (es) 2025-08-01
EP4670718A3 (en) 2026-03-04
US20220323399A1 (en) 2022-10-13
US20220079910A1 (en) 2022-03-17
EP3897610C0 (en) 2025-04-16
AU2023204682A1 (en) 2023-08-10
CA3124316C (en) 2023-07-04
EP3897610B1 (en) 2025-04-16
KR20220002860A (ko) 2022-01-07
EP3897610A1 (en) 2021-10-27
CN113543781A (zh) 2021-10-22
JP2025094189A (ja) 2025-06-24
ES3026709T3 (en) 2025-06-12
PE20220250A1 (es) 2022-02-16
US20250312305A1 (en) 2025-10-09
MX2021007478A (es) 2021-10-13
WO2020127606A1 (en) 2020-06-25
US11571408B2 (en) 2023-02-07

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted