AU2019378077A1 - New therapy - Google Patents

New therapy Download PDF

Info

Publication number
AU2019378077A1
AU2019378077A1 AU2019378077A AU2019378077A AU2019378077A1 AU 2019378077 A1 AU2019378077 A1 AU 2019378077A1 AU 2019378077 A AU2019378077 A AU 2019378077A AU 2019378077 A AU2019378077 A AU 2019378077A AU 2019378077 A1 AU2019378077 A1 AU 2019378077A1
Authority
AU
Australia
Prior art keywords
oligonucleotide
patient
ulcerative colitis
use according
weeks
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2019378077A
Other languages
English (en)
Inventor
Charlotte Admyre
Thomas Knittel
Pernilla SANDWALL
Arezou Zargari
Peter ZERHOUNI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Index Pharmaceuticals AB
Original Assignee
Index Pharmaceuticals AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Index Pharmaceuticals AB filed Critical Index Pharmaceuticals AB
Publication of AU2019378077A1 publication Critical patent/AU2019378077A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2019378077A 2018-11-14 2019-11-14 New therapy Abandoned AU2019378077A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1818579.3 2018-11-14
GBGB1818579.3A GB201818579D0 (en) 2018-11-14 2018-11-14 New therapy
PCT/EP2019/081377 WO2020099585A1 (en) 2018-11-14 2019-11-14 New therapy

Publications (1)

Publication Number Publication Date
AU2019378077A1 true AU2019378077A1 (en) 2021-04-22

Family

ID=64739449

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019378077A Abandoned AU2019378077A1 (en) 2018-11-14 2019-11-14 New therapy

Country Status (10)

Country Link
US (1) US20220218736A1 (https=)
EP (1) EP3880303A1 (https=)
JP (1) JP2022507493A (https=)
KR (1) KR20210092719A (https=)
CN (1) CN113226461A (https=)
AU (1) AU2019378077A1 (https=)
BR (1) BR112021005645A2 (https=)
CA (1) CA3118899A1 (https=)
GB (1) GB201818579D0 (https=)
WO (1) WO2020099585A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4147688A1 (en) 2021-09-09 2023-03-15 InDex Pharmaceuticals AB Enema formulation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5149797A (en) 1990-02-15 1992-09-22 The Worcester Foundation For Experimental Biology Method of site-specific alteration of rna and production of encoded polypeptides
EP2596806A1 (en) * 2011-11-25 2013-05-29 Index Pharmaceuticals AB Method for prevention of colectomy
GB201707503D0 (en) * 2017-05-10 2017-06-21 Index Pharmaceuticals Ab New Therapy 3
GB201707500D0 (en) * 2017-05-10 2017-06-21 Index Pharmaceuticals Ab New therapy
GB201707501D0 (en) * 2017-05-10 2017-06-21 Index Pharmaceuticals Ab New therapy 2

Also Published As

Publication number Publication date
GB201818579D0 (en) 2018-12-26
BR112021005645A2 (pt) 2021-06-29
KR20210092719A (ko) 2021-07-26
JP2022507493A (ja) 2022-01-18
WO2020099585A1 (en) 2020-05-22
US20220218736A1 (en) 2022-07-14
EP3880303A1 (en) 2021-09-22
CN113226461A (zh) 2021-08-06
CA3118899A1 (en) 2020-05-22

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application