AU2019309587B2 - Compositions comprising intermediate non-coding RNA regulators modulating the expression of ETV6 or FOXO1 and uses thereof - Google Patents
Compositions comprising intermediate non-coding RNA regulators modulating the expression of ETV6 or FOXO1 and uses thereof Download PDFInfo
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- AU2019309587B2 AU2019309587B2 AU2019309587A AU2019309587A AU2019309587B2 AU 2019309587 B2 AU2019309587 B2 AU 2019309587B2 AU 2019309587 A AU2019309587 A AU 2019309587A AU 2019309587 A AU2019309587 A AU 2019309587A AU 2019309587 B2 AU2019309587 B2 AU 2019309587B2
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- etv6
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/11—Antisense
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- C12N2310/10—Type of nucleic acid
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- C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C12N2310/141—MicroRNAs, miRNAs
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/323—Chemical structure of the sugar modified ring structure
- C12N2310/3233—Morpholino-type ring
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- Life Sciences & Earth Sciences (AREA)
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- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
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- Public Health (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
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- Neurology (AREA)
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- Toxicology (AREA)
- Epidemiology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1812334.9 | 2018-07-27 | ||
| GBGB1812334.9A GB201812334D0 (en) | 2018-07-27 | 2018-07-27 | Compositions and uses thereof |
| PCT/GB2019/052125 WO2020021291A1 (en) | 2018-07-27 | 2019-07-29 | Compositions comprising intermediate non-coding rna regulators modulating the expression of etv6 or foxo1 and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2019309587A1 AU2019309587A1 (en) | 2021-02-18 |
| AU2019309587B2 true AU2019309587B2 (en) | 2024-09-19 |
Family
ID=63518136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019309587A Active AU2019309587B2 (en) | 2018-07-27 | 2019-07-29 | Compositions comprising intermediate non-coding RNA regulators modulating the expression of ETV6 or FOXO1 and uses thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210292765A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3830111A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2021531317A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20210069626A (cg-RX-API-DMAC7.html) |
| CN (2) | CN120713925A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2019309587B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3107700A1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB201812334D0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2020021291A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11339392B2 (en) | 2016-03-02 | 2022-05-24 | The Board Of Trustees Of The Leland Stanford Junior University | Pan-genotypic agents against influenza virus and methods of using the same |
| US12522827B2 (en) | 2016-03-02 | 2026-01-13 | The Board Of Trustees Of The Leland Stanford Junior University | Pan-genotypic agents against influenza virus and methods of using the same |
| WO2019159884A1 (ja) * | 2018-02-13 | 2019-08-22 | 東レ株式会社 | 認知症の検出のためのキット又はデバイス及び方法 |
| CN115997014A (zh) * | 2020-02-14 | 2023-04-21 | 小利兰·斯坦福大学董事会 | 抗呼吸道病毒的泛基因型药剂及其使用方法 |
| CN114159457B (zh) * | 2021-12-03 | 2023-08-22 | 温州医科大学 | 一种长链非编码rna、其结合蛋白及应用 |
| CN117757930A (zh) * | 2023-11-30 | 2024-03-26 | 四川大学华西医院 | 一种前列腺癌辅助诊断的标志物 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004042406A1 (en) * | 2002-11-05 | 2004-05-21 | Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research | Tel/etv6-mediated inhibition of cell proliferation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090156523A1 (en) * | 2005-07-11 | 2009-06-18 | Irm Llc | Methods and compositions for modulating foxo1 activity and insulin signaling |
| JP2013253031A (ja) * | 2012-06-06 | 2013-12-19 | Nissei Bio Kk | 抗老化関連遺伝子転写促進剤 |
| US11657895B2 (en) * | 2016-05-03 | 2023-05-23 | Institute For Systems Biology | Methods for identifying treatment targets based on multiomics data |
-
2018
- 2018-07-27 GB GBGB1812334.9A patent/GB201812334D0/en not_active Ceased
-
2019
- 2019-07-29 KR KR1020217006078A patent/KR20210069626A/ko not_active Ceased
- 2019-07-29 CA CA3107700A patent/CA3107700A1/en active Pending
- 2019-07-29 CN CN202411972083.0A patent/CN120713925A/zh active Pending
- 2019-07-29 AU AU2019309587A patent/AU2019309587B2/en active Active
- 2019-07-29 CN CN201980064286.0A patent/CN113166214A/zh active Pending
- 2019-07-29 JP JP2021504393A patent/JP2021531317A/ja active Pending
- 2019-07-29 WO PCT/GB2019/052125 patent/WO2020021291A1/en not_active Ceased
- 2019-07-29 EP EP19745738.5A patent/EP3830111A1/en active Pending
- 2019-07-29 US US17/263,465 patent/US20210292765A1/en not_active Abandoned
-
2024
- 2024-05-09 JP JP2024076795A patent/JP2024102292A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004042406A1 (en) * | 2002-11-05 | 2004-05-21 | Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research | Tel/etv6-mediated inhibition of cell proliferation |
Non-Patent Citations (2)
| Title |
|---|
| NEELAM T., et al., 2018, 'Role of Forkhead Box O (FOXO) transcription factor in aging and diseases', Gene., 648, pages 97-105 * |
| YUAN-CHIN, T., et al., 2016, 'Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6', Cancer Letters, 384, pages 1-8 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3830111A1 (en) | 2021-06-09 |
| US20210292765A1 (en) | 2021-09-23 |
| KR20210069626A (ko) | 2021-06-11 |
| WO2020021291A1 (en) | 2020-01-30 |
| CN120713925A (zh) | 2025-09-30 |
| JP2024102292A (ja) | 2024-07-30 |
| CN113166214A (zh) | 2021-07-23 |
| JP2021531317A (ja) | 2021-11-18 |
| CA3107700A1 (en) | 2020-01-30 |
| AU2019309587A1 (en) | 2021-02-18 |
| GB201812334D0 (en) | 2018-09-12 |
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