AU2019306571B2 - Systems and methods for treatment of cancer using alternating electric field generation - Google Patents

Systems and methods for treatment of cancer using alternating electric field generation Download PDF

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Publication number
AU2019306571B2
AU2019306571B2 AU2019306571A AU2019306571A AU2019306571B2 AU 2019306571 B2 AU2019306571 B2 AU 2019306571B2 AU 2019306571 A AU2019306571 A AU 2019306571A AU 2019306571 A AU2019306571 A AU 2019306571A AU 2019306571 B2 AU2019306571 B2 AU 2019306571B2
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Australia
Prior art keywords
electric field
alternating electric
operable
deep
electrodes
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AU2019306571A
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AU2019306571A1 (en
Inventor
Benjamin Hendricks
Kris SMITH
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Dignity Health
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Dignity Health
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0531—Brain cortex electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002—Cancer treatment, e.g. tumour
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37235—Aspects of the external programmer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/37514—Brain implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Electrotherapy Devices (AREA)
AU2019306571A 2018-07-17 2019-07-17 Systems and methods for treatment of cancer using alternating electric field generation Active AU2019306571B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862699146P 2018-07-17 2018-07-17
US62/699,146 2018-07-17
PCT/US2019/042197 WO2020018662A1 (en) 2018-07-17 2019-07-17 Systems and methods for treatment of cancer using alternating electric field generation

Publications (2)

Publication Number Publication Date
AU2019306571A1 AU2019306571A1 (en) 2021-01-21
AU2019306571B2 true AU2019306571B2 (en) 2024-06-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019306571A Active AU2019306571B2 (en) 2018-07-17 2019-07-17 Systems and methods for treatment of cancer using alternating electric field generation

Country Status (7)

Country Link
US (3) US11565111B2 (https=)
EP (1) EP3823714B1 (https=)
JP (3) JP7384895B2 (https=)
CN (1) CN112423836A (https=)
AU (1) AU2019306571B2 (https=)
CA (1) CA3104885A1 (https=)
WO (1) WO2020018662A1 (https=)

Cited By (1)

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US20230414955A1 (en) * 2022-06-27 2023-12-28 Novocure Gmbh Closed-Loop Technique to Reduce Electrosensation While Treating a Subject Using Alternating Electric Fields

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US12403305B2 (en) 2016-06-27 2025-09-02 Galvanize Therapeutics, Inc. Immunostimulation in the treatment of viral infection
DK4218641T3 (da) 2017-12-26 2025-08-18 Galvanize Therapeutics Inc Optimering af energilevering til forskellige anvendelser
CN112423836A (zh) * 2018-07-17 2021-02-26 迪格尼提健康公司 利用交变电场产生治疗癌症的系统和方法
JP7551648B2 (ja) 2019-04-18 2024-09-17 ガルヴァナイズ セラピューティクス，インコーポレイテッド 異常組織を治療するための器械、及びシステム、
AU2020314830B2 (en) 2019-07-16 2026-01-22 Galvanize Therapeutics, Inc. Treatment of the reproductive tract with pulsed electric fields
GB2604400A (en) 2021-03-05 2022-09-07 Qv Bioelectronics Ltd Biphasic injectable electrode
GB2604397A (en) 2021-03-05 2022-09-07 Qv Bioelectronics Ltd Cranial Prosthetic
WO2023168034A1 (en) * 2022-03-03 2023-09-07 Medtronic, Inc. Electrode configurations for electric field therapy
US20250101406A1 (en) * 2022-09-23 2025-03-27 Novocure Gmbh 3d models for predicting treatment responses to alternating electric fields
CN119455251A (zh) * 2024-11-05 2025-02-18 海南派云科技有限公司 一种基于多模式的肿瘤治疗电场调节系统

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US6340353B1 (en) * 1996-09-30 2002-01-22 Jeanne K. Pomatto Manufacture of cranial remodeling orthosis
US20050021118A1 (en) * 2000-07-13 2005-01-27 Chris Genau Apparatuses and systems for applying electrical stimulation to a patient
AU2003299471A1 (en) 2002-05-07 2004-05-13 Kai Kroll Method and device for treating concer with electrical therapy in conjunction with chemotherapeutic agents and radiation therapy
US7826902B2 (en) * 2006-02-24 2010-11-02 Medtronic, Inc. User interface with 2D views for configuring stimulation therapy
US20080046023A1 (en) * 2006-08-16 2008-02-21 Fischell David R Electrode switch for a brain neuropacemaker
US8364284B2 (en) * 2008-09-15 2013-01-29 Boston Scientific Neuromodulation Corporation Implantable electric stimulation system and methods of making and using
GB0821325D0 (en) * 2008-11-21 2008-12-31 Ucl Business Plc Method and apparatus for performing deep brain stimulation with an electric field
EP2413833A1 (en) * 2009-03-31 2012-02-08 AngioDynamics, Inc. System and method for estimating a treatment region for a medical treatment device and for interactively planning a treatment of a patient
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US8996115B2 (en) * 2011-04-07 2015-03-31 Greatbatch, Ltd. Charge balancing for arbitrary waveform generator and neural stimulation application
WO2015010682A1 (de) * 2013-07-23 2015-01-29 König Florian M Nachbildung und erweiterung von naturnahen sferics-signalfolgen als elektromagnetisches wechselfeld
WO2016179712A1 (en) 2015-05-14 2016-11-17 London Health Sciences Centre Research Inc. Intratumoral modulation therapy
WO2016191807A1 (en) * 2015-05-31 2016-12-08 Saluda Medical Pty Ltd Brain neurostimulator electrode fitting
US10525267B2 (en) * 2015-06-02 2020-01-07 Battelle Memorial Institute Closed loop deep brain stimulation systems and methods
US10188851B2 (en) * 2015-10-28 2019-01-29 Novocure Limited TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements
US11446487B2 (en) * 2016-09-23 2022-09-20 Beth Israel Deaconess Medical Center, Inc. System and methods for cancer treatment using alternating electric fields
CN106823140B (zh) * 2017-01-14 2023-03-03 北京品驰医疗设备有限公司 一种可调整电场方向的骶神经刺激器
CN112423836A (zh) 2018-07-17 2021-02-26 迪格尼提健康公司 利用交变电场产生治疗癌症的系统和方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230414955A1 (en) * 2022-06-27 2023-12-28 Novocure Gmbh Closed-Loop Technique to Reduce Electrosensation While Treating a Subject Using Alternating Electric Fields

Also Published As

Publication number Publication date
EP3823714B1 (en) 2025-05-07
JP2021531090A (ja) 2021-11-18
JP2023184733A (ja) 2023-12-28
JP7384895B2 (ja) 2023-11-21
CA3104885A1 (en) 2020-01-23
EP3823714A1 (en) 2021-05-26
US20230149713A1 (en) 2023-05-18
CN112423836A (zh) 2021-02-26
WO2020018662A1 (en) 2020-01-23
US11565111B2 (en) 2023-01-31
US12214196B2 (en) 2025-02-04
JP2026042984A (ja) 2026-03-11
JP7807153B2 (ja) 2026-01-27
US20210308455A1 (en) 2021-10-07
US20250144424A1 (en) 2025-05-08
EP3823714A4 (en) 2022-04-20
AU2019306571A1 (en) 2021-01-21

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