AU2017349924B2 - Apparatus and methods for predicting therapy outcome - Google Patents

Apparatus and methods for predicting therapy outcome Download PDF

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Publication number
AU2017349924B2
AU2017349924B2 AU2017349924A AU2017349924A AU2017349924B2 AU 2017349924 B2 AU2017349924 B2 AU 2017349924B2 AU 2017349924 A AU2017349924 A AU 2017349924A AU 2017349924 A AU2017349924 A AU 2017349924A AU 2017349924 B2 AU2017349924 B2 AU 2017349924B2
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computer processor
magnetic stimulation
network activity
given
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AU2017349924A1 (en
Inventor
Uri ALYAGON
Amir Geva
Dror HAOR
Gaby S. PELL
Ziv PEREMEN
Yiftach Roth
Boaz SADEH
Ronen Segal
Revital Shani-Hershkovich
Abraham Zangen
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BG Negev Technologies and Applications Ltd
Brainsway Ltd
Firefly Neuroscience Ltd
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BG Negev Technologies and Applications Ltd
Elminda Ltd
Brainsway Ltd
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0006ECG or EEG signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/16Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/165Evaluating the state of mind, e.g. depression, anxiety
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/16Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/168Evaluating attention deficit, hyperactivity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30Input circuits therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/377Electroencephalography [EEG] using evoked responses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076Diagnosing or monitoring particular conditions of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7275Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • A61N2/006Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Social Psychology (AREA)
  • Educational Technology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Signal Processing (AREA)
  • Neurosurgery (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Magnetic Treatment Devices (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2017349924A 2016-10-25 2017-10-25 Apparatus and methods for predicting therapy outcome Active AU2017349924B2 (en)

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US201662412598P 2016-10-25 2016-10-25
US62/412,598 2016-10-25
PCT/IL2017/051163 WO2018078619A1 (en) 2016-10-25 2017-10-25 Apparatus and methods for predicting therapy outcome

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AU2017349924B2 true AU2017349924B2 (en) 2024-09-12

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US (1) US11400289B2 (cg-RX-API-DMAC7.html)
EP (1) EP3532162B1 (cg-RX-API-DMAC7.html)
JP (1) JP7048598B2 (cg-RX-API-DMAC7.html)
CN (1) CN110114115B (cg-RX-API-DMAC7.html)
AU (1) AU2017349924B2 (cg-RX-API-DMAC7.html)
CA (1) CA3041605A1 (cg-RX-API-DMAC7.html)
IL (1) IL266176B (cg-RX-API-DMAC7.html)
WO (1) WO2018078619A1 (cg-RX-API-DMAC7.html)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2670299A4 (en) 2011-02-03 2017-08-09 The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center Method and system for use in monitoring neural activity in a subject's brain
US9782585B2 (en) 2013-08-27 2017-10-10 Halo Neuro, Inc. Method and system for providing electrical stimulation to a user
EP3038700B1 (en) 2013-08-27 2020-03-11 Halo Neuro, Inc. Method and system for providing electrical stimulation to a user
US20180001107A1 (en) 2016-07-01 2018-01-04 Btl Holdings Limited Aesthetic method of biological structure treatment by magnetic field
US11247039B2 (en) 2016-05-03 2022-02-15 Btl Healthcare Technologies A.S. Device including RF source of energy and vacuum system
US11534619B2 (en) 2016-05-10 2022-12-27 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US10583287B2 (en) 2016-05-23 2020-03-10 Btl Medical Technologies S.R.O. Systems and methods for tissue treatment
US10556122B1 (en) 2016-07-01 2020-02-11 Btl Medical Technologies S.R.O. Aesthetic method of biological structure treatment by magnetic field
US11141219B1 (en) 2016-08-16 2021-10-12 BTL Healthcare Technologies, a.s. Self-operating belt
CN117462844A (zh) 2017-02-02 2024-01-30 福禄神经学公司 用于经颅直流电刺激tdcs的头戴设备和包括头戴设备的系统
WO2018182534A1 (en) * 2017-03-31 2018-10-04 Agency For Science, Technology And Research A computer system for acquiring a control command
US10507324B2 (en) 2017-11-17 2019-12-17 Halo Neuro, Inc. System and method for individualizing modulation
CN108742607A (zh) * 2018-06-29 2018-11-06 南阳市中心医院 一种神经内科介入治疗装置
US12156689B2 (en) 2019-04-11 2024-12-03 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
KR102609208B1 (ko) 2019-04-11 2023-12-05 비티엘 메디컬 솔루션스 에이.에스. 고주파 및 자기 에너지에 의한 생물학적 구조들의 심미적 치료를 위한 방법들 및 디바이스들
CN110537929B (zh) * 2019-08-23 2022-11-04 杭州曼安智能科技有限公司 一种基于ssvep的注意力测评方法、训练方法以及脑机接口
CN110840411B (zh) * 2019-12-06 2022-03-11 深圳市德力凯医疗设备股份有限公司 一种麻醉深度的测量装置、存储介质及电子设备
US12343157B2 (en) 2020-04-14 2025-07-01 Neurotype Inc. Assessing motivated attention with cue reactivity
US11878167B2 (en) 2020-05-04 2024-01-23 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
ES2993637T3 (en) 2020-05-04 2025-01-03 Btl Healthcare Technologies As Device for unattended treatment of a patient
CN111839511B (zh) * 2020-07-21 2021-08-10 浙江大学 一种磁兼容神经探针及其制备方法
WO2022056652A1 (zh) * 2020-09-15 2022-03-24 洪硕宏 评估跨颅磁刺激对忧郁症患者是否有效的辅助判断装置
CN114259239A (zh) * 2020-09-15 2022-04-01 洪硕宏 评估跨颅磁刺激对忧郁症患者是否有效的辅助判断装置
US11571541B2 (en) 2020-10-27 2023-02-07 David Richardson Hubbard, JR. Apparatus and methods of transcranial stimulation to adjust sensory cortical dendritic spine neck membrane potentials for altering consciousness
WO2022172792A1 (ja) * 2021-02-12 2022-08-18 学校法人慶應義塾 症状判定装置及び症状判定プログラム
KR20240041931A (ko) * 2021-07-06 2024-04-01 시냅티카 테라퓨틱스, 인크. 뇌 네트워크에 대해 개별 표적화된 비-침습성 자극을 제공하기 위한 시스템 및 방법
CN113545792B (zh) * 2021-07-20 2024-06-18 深圳市人民医院 一种基于tms-eeg的神经生物标记物的检测方法
EP4415812A1 (en) 2021-10-13 2024-08-21 BTL Medical Solutions a.s. Devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
CN114081493B (zh) * 2021-12-07 2024-02-27 杭州睿笛生物科技有限公司 一种抑郁症的辅助检测评估方法
CN115644890A (zh) * 2022-11-15 2023-01-31 南京左右脑医疗科技集团有限公司 大脑状态识别方法、装置和存储介质
IL321514A (en) * 2022-12-16 2025-08-01 Graymatters Health Ltd Prognosis prediction
US11980476B1 (en) * 2023-02-16 2024-05-14 Neuralytix, Llc Intraoperative neural monitoring method
CN116510183B (zh) * 2023-06-28 2023-09-19 南昌大学第一附属医院 经颅磁刺激设备、电子设备及存储介质
CN116764106A (zh) * 2023-06-29 2023-09-19 中国医学科学院生物医学工程研究所 一种用于治疗多动症的头戴式治疗仪及治疗方法
CN117898744B (zh) * 2024-02-06 2024-07-16 中国科学院心理研究所 脑电数据分析装置、第二设备、数据采集及处理系统
US12279880B1 (en) 2024-08-09 2025-04-22 Neuralytix, Llc System and method for assessing nerve health during a spinal decompression procedure
US12279879B1 (en) 2024-08-09 2025-04-22 Neuralytix, Llc System and method for empirical assessment of nerve health during a spinal decompression procedure
US12279881B1 (en) 2024-08-09 2025-04-22 Neuralytix, Llc System and method for assessing nerve health during a spinal decompression procedure using a calculated nerve function index

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2912902A (en) 2000-10-20 2002-04-29 Us Gov Health & Human Serv Coil for magnetic stimulation and methods for using the same
US7418290B2 (en) * 2003-05-06 2008-08-26 Aspect Medical Systems, Inc. System and method of assessment of the efficacy of treatment of neurological disorders using the electroencephalogram
US7706871B2 (en) 2003-05-06 2010-04-27 Nellcor Puritan Bennett Llc System and method of prediction of response to neurological treatment using the electroencephalogram
US7976451B2 (en) 2005-06-16 2011-07-12 The United States Of America As Represented By The Department Of Health And Human Services Transcranial magnetic stimulation system and methods
EP2024901A2 (en) 2006-05-25 2009-02-18 Elminda Ltd. Neuropsychological spatiotemporal pattern recognition
WO2008070001A2 (en) 2006-12-01 2008-06-12 Beth Israel Deaconess Medical Center, Inc. Transcranial magnetic stimulation (tms) methods and apparatus
WO2009069134A2 (en) 2007-11-29 2009-06-04 Elminda Ltd. Functional analysis of neurophysiological data
WO2009069136A2 (en) 2007-11-29 2009-06-04 Elminda Ltd. Clinical applications of neuropsychological pattern analysis and modeling
US20120203130A1 (en) * 2009-07-22 2012-08-09 Armin Bernhard Tinnitus Therapy Device
US20110224571A1 (en) * 2009-11-16 2011-09-15 Alvaro Pascual-Leone Non-invasive methods for evaluating cortical plasticity impairments
CA2786380C (en) * 2010-01-18 2020-07-14 Elminda Ltd. Method and system for weighted analysis of neurophysiological data
EP2651496A4 (en) * 2010-12-14 2014-07-09 Univ California DEVICES, SYSTEMS AND METHODS OF TREATING MEDICAL DISEASES
EP2734107B1 (en) * 2011-07-20 2017-05-24 Elminda Ltd. Method and system for estimating brain concussion
US9636517B2 (en) 2012-02-13 2017-05-02 Brainsway, Ltd. Use of transcranial magnetic stimulation to modulate permeability of the blood-brain barrier
US10335606B2 (en) 2012-02-13 2019-07-02 Brainsway, Ltd. Use of transcranial magnetic stimulation to modulate permeability of the blood-brain barrier
EA201400987A3 (ru) 2012-04-06 2015-10-30 Ньюпорт Брейн Рисёч Лаборатори Инк. Rtms на гармониках биологических сигналов
KR20150085007A (ko) 2012-11-13 2015-07-22 엘마인다 리미티드 시공간 분할을 이용한 신경 생리학적 데이터 분석
US9254394B2 (en) 2013-02-21 2016-02-09 Brainsway, Ltd. Central base coils for deep transcranial magnetic stimulation
US9533168B2 (en) 2013-02-21 2017-01-03 Brainsway, Ltd. Unilateral coils for deep transcranial magnetic stimulation
US9248308B2 (en) 2013-02-21 2016-02-02 Brainsway, Ltd. Circular coils for deep transcranial magnetic stimulation
US9802058B2 (en) 2013-02-21 2017-10-31 Brainsway, Ltd. Central base coils for deep transcranial magnetic stimulation
US9808642B2 (en) 2013-02-21 2017-11-07 Brainsway, Ltd. Circular coils for deep transcranial magnetic stimulation
KR20150023364A (ko) 2013-03-15 2015-03-05 넥스팀 오와이 Tms 투여량 평가 및 발작 검출을 위한 방법 및 시스템
CA2965615A1 (en) 2013-11-13 2015-05-21 Elminda Ltd. Method and system for managing pain
WO2016046830A2 (en) 2014-09-28 2016-03-31 Elminda Ltd. Brain stimulation tool configuration
WO2017072777A1 (en) 2015-11-01 2017-05-04 Elminda Ltd. Method and system for estimating potential distribution on cortical surface

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Publication number Publication date
AU2017349924A1 (en) 2019-05-23
EP3532162A1 (en) 2019-09-04
US20190247654A1 (en) 2019-08-15
JP7048598B2 (ja) 2022-04-05
IL266176A (en) 2019-06-30
EP3532162B1 (en) 2024-07-24
JP2020503084A (ja) 2020-01-30
WO2018078619A1 (en) 2018-05-03
CN110114115B (zh) 2023-06-06
IL266176B (en) 2022-08-01
US11400289B2 (en) 2022-08-02
CA3041605A1 (en) 2018-05-03
CN110114115A (zh) 2019-08-09

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