AU2016380168B2 - Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector - Google Patents

Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector Download PDF

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Publication number
AU2016380168B2
AU2016380168B2 AU2016380168A AU2016380168A AU2016380168B2 AU 2016380168 B2 AU2016380168 B2 AU 2016380168B2 AU 2016380168 A AU2016380168 A AU 2016380168A AU 2016380168 A AU2016380168 A AU 2016380168A AU 2016380168 B2 AU2016380168 B2 AU 2016380168B2
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AU
Australia
Prior art keywords
fluorometer
carrier
receptacle
intensity
sensor
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AU2016380168A
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English (en)
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AU2016380168A1 (en
Inventor
James BUI
David Opalsky
Srajan RAGHUWANSHI
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Gen Probe Inc
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Gen Probe Inc
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Publication of AU2016380168A1 publication Critical patent/AU2016380168A1/en
Application granted granted Critical
Publication of AU2016380168B2 publication Critical patent/AU2016380168B2/en
Priority to AU2022203734A priority Critical patent/AU2022203734B2/en
Priority to AU2024200422A priority patent/AU2024200422B2/en
Active legal-status Critical Current
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0332—Cuvette constructions with temperature control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • G01N21/276—Calibration, base line adjustment, drift correction with alternation of sample and standard in optical path
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0453—Multiple carousels working in parallel
    • G01N2035/0455—Coaxial carousels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0475—Details of actuating means for conveyors or pipettes electric, e.g. stepper motor, solenoid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0482—Transmission
    • G01N2035/0484—Belt or chain
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/04—Batch operation; multisample devices
    • G01N2201/0407—Batch operation; multisample devices with multiple optical units, e.g. one per sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/04—Batch operation; multisample devices
    • G01N2201/0415—Carrusel, sequential
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/127—Calibration; base line adjustment; drift compensation
    • G01N2201/12723—Self check capacity; automatic, periodic step of checking
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Mathematical Physics (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Optics & Photonics (AREA)
AU2016380168A 2015-12-31 2016-12-22 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector Active AU2016380168B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2022203734A AU2022203734B2 (en) 2015-12-31 2022-05-31 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
AU2024200422A AU2024200422B2 (en) 2015-12-31 2024-01-23 System for Measuring Optical Signal Detector Performance

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562274027P 2015-12-31 2015-12-31
US62/274,027 2015-12-31
PCT/US2016/068384 WO2017117011A1 (en) 2015-12-31 2016-12-22 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2022203734A Division AU2022203734B2 (en) 2015-12-31 2022-05-31 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector

Publications (2)

Publication Number Publication Date
AU2016380168A1 AU2016380168A1 (en) 2018-08-09
AU2016380168B2 true AU2016380168B2 (en) 2022-03-10

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Family Applications (3)

Application Number Title Priority Date Filing Date
AU2016380168A Active AU2016380168B2 (en) 2015-12-31 2016-12-22 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
AU2022203734A Active AU2022203734B2 (en) 2015-12-31 2022-05-31 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
AU2024200422A Active AU2024200422B2 (en) 2015-12-31 2024-01-23 System for Measuring Optical Signal Detector Performance

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2022203734A Active AU2022203734B2 (en) 2015-12-31 2022-05-31 Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
AU2024200422A Active AU2024200422B2 (en) 2015-12-31 2024-01-23 System for Measuring Optical Signal Detector Performance

Country Status (7)

Country Link
US (4) US10190984B2 (https=)
EP (2) EP3397947B1 (https=)
JP (3) JP6845858B2 (https=)
CN (1) CN108369180B (https=)
AU (3) AU2016380168B2 (https=)
CA (1) CA3008891C (https=)
WO (1) WO2017117011A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6845858B2 (ja) 2015-12-31 2021-03-24 ジェン−プローブ・インコーポレーテッド サンプルを分析し、光信号検出器の性能を監視するシステム及び方法
WO2020032905A2 (en) * 2018-08-09 2020-02-13 Hacettepe Universitesi An experiment assembly for evaluating equipment performance
CN109521197B (zh) * 2018-12-29 2022-03-11 重庆鼎润医疗器械有限责任公司 一种多通道荧光免疫分析仪
GB202001397D0 (en) * 2020-01-31 2020-03-18 Odx Innovations Ltd Apparatus, system and method for measuring properties of a sample
EP4123309A4 (en) * 2020-03-17 2024-04-10 Hitachi High-Tech Corporation AUTOMATIC ANALYSIS DEVICE
CN113567690B (zh) * 2020-04-28 2024-10-01 深圳迎凯生物科技有限公司 孵育组件、孵育装置和自动分析装置
US20240302279A1 (en) * 2020-12-21 2024-09-12 Endress+Hauser Conducta Gmbh+Co. Kg Optochemical sensor and method for measuring luminescing analytes in a measurement medium
US20250155460A1 (en) * 2022-02-14 2025-05-15 Hitachi High-Tech Corporation Parts Anomaly Detection System, Automatic Analyzer and Parts Anomaly Detection Method
US20240329212A1 (en) * 2023-03-27 2024-10-03 Rosemount Aerospace Inc. Optical imaging device degradation check

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050287040A1 (en) * 2004-06-29 2005-12-29 Molecular Devices Corporation Fluorescence validation plate
US20130344613A1 (en) * 2012-06-14 2013-12-26 Gen-Probe Incorporated Use of a fluorescent material to detect failure or deteriorated performance of a fluorometer

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5612200A (en) 1992-06-24 1997-03-18 Gen-Probe Incorporated Method and kit for destroying ability of nucleic acid to be amplified
AU699232B2 (en) 1994-03-10 1998-11-26 Gen-Probe Incorporated Method for suppressing inhibition of enzyme-mediated reactions by ionic detergents
DE69530323T2 (de) * 1994-09-02 2004-02-12 BD Biosciences, Systems and Reagents, Inc., San Jose Verfahren und vorrichtung zur eichung eines optischen abtasters
US6066458A (en) 1998-05-18 2000-05-23 Becton, Dickinson And Company Methods, apparatus and computer program products for determining quantities of nucleic acid sequences in samples using standard curves and amplification ratio estimates
ES2330812T3 (es) 1998-07-02 2009-12-15 Gen-Probe Incorporated Antorchas moleculares.
DE19955362B4 (de) * 1999-11-17 2004-07-08 Wagner Alarm- Und Sicherungssysteme Gmbh Streulichtdetektor
CA2868618C (en) 2002-10-16 2017-05-23 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
AU2004233069C1 (en) 2003-04-17 2010-05-27 Gen-Probe Incorporated Compositions and methods for determining the presence of SARS coronavirus in a sample
ATE542917T1 (de) 2003-05-19 2012-02-15 Gen Probe Inc Zusammensetzungen, verfahren und kits zur bestimmung des vorhandenseins von trichomonas vaginalis in einer testprobe
US20050197580A1 (en) * 2004-02-19 2005-09-08 Scott Ferguson Synthetic calibration standard for photonic response of tissues
EP2286845B1 (en) 2004-03-05 2016-11-16 Gen-Probe Incorporated Reagents and method for use in deactivating nucleic acids
JP2006066983A (ja) * 2004-08-24 2006-03-09 Konica Minolta Medical & Graphic Inc 面積階調画像形成方法および面積階調画像形成装置。
CA2898814C (en) 2004-08-27 2015-12-29 Gen-Probe Incorporated Single-primer nucleic acid amplification methods
US7964413B2 (en) 2005-03-10 2011-06-21 Gen-Probe Incorporated Method for continuous mode processing of multiple reaction receptacles in a real-time amplification assay
CA2627259C (en) 2005-11-14 2016-02-23 Gen-Probe Incorporated Parametric calibration method
JP2008209348A (ja) * 2007-02-28 2008-09-11 Matsushita Electric Ind Co Ltd 分析装置、および分析装置状態判定方法
JP2009031202A (ja) * 2007-07-30 2009-02-12 Hitachi High-Technologies Corp 自動分析装置
EP3663004B1 (en) 2009-05-15 2022-01-26 Gen-Probe Incorporated Method and apparatus for performing a magnetic separation procedure
CN103814289A (zh) * 2011-07-22 2014-05-21 比奥森西亚专利有限公司 用于发光免疫测定的读取器装置
JP5939833B2 (ja) * 2012-02-24 2016-06-22 株式会社日立ハイテクノロジーズ 自動分析装置
JP6244556B2 (ja) * 2012-04-25 2017-12-13 パナソニックＩｐマネジメント株式会社 試料保持担体およびそれを用いた蛍光検出装置
DE112014003484B4 (de) 2013-08-27 2023-03-02 Hitachi High-Tech Corporation Nucleinsäure-Analysenvorrichtung und Nucleinsäure-Diagnoseverfahren
JP6287195B2 (ja) 2013-12-26 2018-03-07 東ソー株式会社 蛍光測定装置
JP6845858B2 (ja) 2015-12-31 2021-03-24 ジェン−プローブ・インコーポレーテッド サンプルを分析し、光信号検出器の性能を監視するシステム及び方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050287040A1 (en) * 2004-06-29 2005-12-29 Molecular Devices Corporation Fluorescence validation plate
US20130344613A1 (en) * 2012-06-14 2013-12-26 Gen-Probe Incorporated Use of a fluorescent material to detect failure or deteriorated performance of a fluorometer

Also Published As

Publication number Publication date
AU2016380168A1 (en) 2018-08-09
JP2019504315A (ja) 2019-02-14
JP7320480B2 (ja) 2023-08-03
US20200355610A1 (en) 2020-11-12
US10190984B2 (en) 2019-01-29
JP6845858B2 (ja) 2021-03-24
EP3764079A1 (en) 2021-01-13
WO2017117011A1 (en) 2017-07-06
US10739263B2 (en) 2020-08-11
CA3008891A1 (en) 2017-07-06
US20170191933A1 (en) 2017-07-06
EP3764079B1 (en) 2023-08-09
AU2022203734B2 (en) 2023-10-26
AU2024200422A1 (en) 2024-02-08
JP2022093423A (ja) 2022-06-23
US20220364988A1 (en) 2022-11-17
CN108369180A (zh) 2018-08-03
US11402330B2 (en) 2022-08-02
CN108369180B (zh) 2022-12-16
US20190128810A1 (en) 2019-05-02
EP3397947B1 (en) 2020-04-29
CA3008891C (en) 2024-02-20
AU2024200422B2 (en) 2024-05-09
AU2022203734A1 (en) 2022-06-23
EP3397947A1 (en) 2018-11-07
US11726041B2 (en) 2023-08-15
JP2020197543A (ja) 2020-12-10

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