AU2016324920B2 - Dactinomycin compositions and methods for the treatment of acute myeloid leukemia - Google Patents

Dactinomycin compositions and methods for the treatment of acute myeloid leukemia Download PDF

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Publication number
AU2016324920B2
AU2016324920B2 AU2016324920A AU2016324920A AU2016324920B2 AU 2016324920 B2 AU2016324920 B2 AU 2016324920B2 AU 2016324920 A AU2016324920 A AU 2016324920A AU 2016324920 A AU2016324920 A AU 2016324920A AU 2016324920 B2 AU2016324920 B2 AU 2016324920B2
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composition
administered
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dactinomycin
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AU2016324920A
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AU2016324920A1 (en
Inventor
Brunangelo Falini
Maria Martelli
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2016324920A 2015-09-14 2016-09-13 Dactinomycin compositions and methods for the treatment of acute myeloid leukemia Active AU2016324920B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562218433P 2015-09-14 2015-09-14
US62/218,433 2015-09-14
PCT/EP2016/071599 WO2017046108A1 (en) 2015-09-14 2016-09-13 Dactinomycin compositions and methods for the treatment of acute myeloid leukemia

Publications (2)

Publication Number Publication Date
AU2016324920A1 AU2016324920A1 (en) 2018-04-05
AU2016324920B2 true AU2016324920B2 (en) 2022-03-03

Family

ID=56896582

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016324920A Active AU2016324920B2 (en) 2015-09-14 2016-09-13 Dactinomycin compositions and methods for the treatment of acute myeloid leukemia

Country Status (7)

Country Link
US (2) US10335416B2 (es)
EP (1) EP3349759B1 (es)
JP (1) JP7001599B2 (es)
AU (1) AU2016324920B2 (es)
CA (1) CA2998042C (es)
ES (1) ES2809805T3 (es)
WO (1) WO2017046108A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2998042C (en) 2015-09-14 2022-07-05 Brunangelo Falini Dactinomycin compositions and methods for the treatment of acute myeloid leukemia
EP3512560A4 (en) 2016-09-13 2020-05-27 Rasna Research Inc. DACTINOMYCIN COMPOSITIONS AND METHODS FOR TREATING MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA
WO2018175746A1 (en) 2017-03-24 2018-09-27 Kura Oncology, Inc. Methods for treating hematological malignancies and ewing's sarcoma
WO2020069027A1 (en) * 2018-09-26 2020-04-02 Kura Oncology, Inc. Treatment of hematological malignancies with inhibitors of menin
KR20230128629A (ko) * 2022-02-28 2023-09-05 한국유나이티드제약 주식회사 향상된 용해도를 가지는 닥티노마이신 함유 약학조성물의 제조방법
CN116942834B (zh) * 2023-06-12 2024-04-05 新乡医学院 包含核仁应激诱导剂的抗肿瘤药物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060111358A1 (en) * 2002-10-08 2006-05-25 De Bont Eveline S Treatment of aml

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US20070010466A1 (en) * 2005-07-06 2007-01-11 Branimir Sikic Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer
EP2397149A1 (en) 2010-06-17 2011-12-21 Hil-Invent Ges.M.B.H. Pharmaceutical preparation comprising actinomycin D for the treatment of B-CLL in patients having del(17p)
ES2685619T3 (es) 2013-12-30 2018-10-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinación de un compuesto de arsénico y al menos un retinoide para tratar la leucemia mielógena aguda
CA2998042C (en) 2015-09-14 2022-07-05 Brunangelo Falini Dactinomycin compositions and methods for the treatment of acute myeloid leukemia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060111358A1 (en) * 2002-10-08 2006-05-25 De Bont Eveline S Treatment of aml

Also Published As

Publication number Publication date
US20180207168A1 (en) 2018-07-26
US10335416B2 (en) 2019-07-02
ES2809805T3 (es) 2021-03-05
AU2016324920A1 (en) 2018-04-05
CA2998042A1 (en) 2017-03-23
US20190314380A1 (en) 2019-10-17
EP3349759A1 (en) 2018-07-25
JP2018526460A (ja) 2018-09-13
WO2017046108A1 (en) 2017-03-23
EP3349759B1 (en) 2020-05-20
US11337983B2 (en) 2022-05-24
CA2998042C (en) 2022-07-05
JP7001599B2 (ja) 2022-01-19

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