AU2016235484B2 - Methods and compositions to inhibit symptoms associated with veisalgia - Google Patents

Methods and compositions to inhibit symptoms associated with veisalgia Download PDF

Info

Publication number
AU2016235484B2
AU2016235484B2 AU2016235484A AU2016235484A AU2016235484B2 AU 2016235484 B2 AU2016235484 B2 AU 2016235484B2 AU 2016235484 A AU2016235484 A AU 2016235484A AU 2016235484 A AU2016235484 A AU 2016235484A AU 2016235484 B2 AU2016235484 B2 AU 2016235484B2
Authority
AU
Australia
Prior art keywords
alcohol
pharmaceutical composition
intake
amount
fexofenadine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2016235484A
Other languages
English (en)
Other versions
AU2016235484A1 (en
Inventor
Jacqueline M. Iversen
James M. Iversen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2016235484A1 publication Critical patent/AU2016235484A1/en
Application granted granted Critical
Publication of AU2016235484B2 publication Critical patent/AU2016235484B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/603—Salicylic acid; Derivatives thereof having further aromatic rings, e.g. diflunisal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AU2016235484A 2015-03-26 2016-03-18 Methods and compositions to inhibit symptoms associated with veisalgia Active AU2016235484B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562138665P 2015-03-26 2015-03-26
US62/138,665 2015-03-26
PCT/US2016/023200 WO2016154028A1 (en) 2015-03-26 2016-03-18 Methods and compositions to inhibit symptoms associated with veisalgia

Publications (2)

Publication Number Publication Date
AU2016235484A1 AU2016235484A1 (en) 2017-10-12
AU2016235484B2 true AU2016235484B2 (en) 2021-02-18

Family

ID=56976188

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016235484A Active AU2016235484B2 (en) 2015-03-26 2016-03-18 Methods and compositions to inhibit symptoms associated with veisalgia

Country Status (15)

Country Link
US (3) US10420756B2 (OSRAM)
EP (2) EP3973957A1 (OSRAM)
JP (1) JP6851365B2 (OSRAM)
KR (1) KR102597910B1 (OSRAM)
CN (2) CN107635549A (OSRAM)
AU (1) AU2016235484B2 (OSRAM)
BR (1) BR112017020307B1 (OSRAM)
CA (1) CA2980162C (OSRAM)
ES (1) ES2926494T3 (OSRAM)
IL (1) IL254641B2 (OSRAM)
MX (2) MX390011B (OSRAM)
NZ (1) NZ735777A (OSRAM)
PL (1) PL3273952T3 (OSRAM)
WO (1) WO2016154028A1 (OSRAM)
ZA (1) ZA201706794B (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017020307B1 (pt) 2015-03-26 2023-11-07 Jacqueline M. Iversen Usos de uma combinação de naproxeno e fexofenadina
US20180360811A1 (en) 2017-06-16 2018-12-20 SEN-JAM Pharmaceutical LLC Methods and Compositions to Inhibit Symptoms Associated with Viral Upper Respiratory Tract Infections
US10874653B2 (en) 2017-08-30 2020-12-29 SEN-JAM Pharmaceutical LLC Methods and compositions to inhibit adverse effects associated with vaccinations
EP3684347A4 (en) * 2017-09-18 2021-10-13 Sen-Jam Pharmaceutical LLC METHODS AND COMPOSITIONS TO INHIBIT SYMPTOMS ASSOCIATED WITH OPIOID WITHDRAWAL
US11129803B2 (en) 2017-09-18 2021-09-28 SEN-JAM Pharmaceutical LLC Methods and compositions to inhibit tolerance to opioids
EP3684360A4 (en) * 2017-09-18 2021-10-13 Sen-Jam Pharmaceutical LLC METHODS AND COMPOSITIONS TO INHIBIT OPIOID DEPENDENCE
WO2019178516A1 (en) * 2018-03-16 2019-09-19 SEN-JAM Pharmaceutical LLC Methods and compositions to treat enteropathic arthritis

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4975426A (en) * 1987-06-08 1990-12-04 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US5053396A (en) * 1985-08-27 1991-10-01 Blass David H Therapeutic composition
WO1992005783A1 (en) * 1990-09-28 1992-04-16 Merck & Co., Inc. Ibuprofen-antihistamine combinations
WO1999015173A1 (en) * 1997-09-19 1999-04-01 The Procter & Gamble Company Compositions and methods for treating respiratory disorders
US20040253311A1 (en) * 2002-12-18 2004-12-16 Roger Berlin Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines
US20050203105A1 (en) * 2002-08-15 2005-09-15 Tan Oon T. Composition and method for controlling alcohol-induced facial flushing in susceptible humans
GB2435418A (en) * 2006-02-28 2007-08-29 Amalan Selvarajah Composition for preventing and alleviating alcohol hangover
US20080113021A1 (en) * 2006-10-25 2008-05-15 Robert Shen Ibuprofen composition
US20090306025A1 (en) * 2008-05-30 2009-12-10 Fairfield Clinical Trials, Llc Method and composition for skin inflammation and discoloration
WO2015073573A1 (en) * 2013-11-14 2015-05-21 Jacobs Michael M Compositions and methods for the prevention and treatment of alcohol-induced hangover syndrome

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4075426A (en) 1976-03-12 1978-02-21 Harvey Mitchell Gould Parallel silent communicator
US4496548A (en) * 1983-02-04 1985-01-29 Moldowan Mervin J Composition and method for reducing hangover
RU2167657C2 (ru) * 1992-08-03 2001-05-27 Сепракор, Инк. Фармацевтическая композиция для лечения аллергических заболеваний, способ антигистаминного лечения, применение композиции для получения лекарственного препарата
ES2206567T3 (es) 1995-04-21 2004-05-16 Sekisui Kagaku Kogyo Kabushiki Kaisha Preparaciones externas para el tratamiento de dermatosis.
US6077539A (en) * 1996-11-12 2000-06-20 Pozen, Inc. Treatment of migraine headache
DE19708209C2 (de) 1997-02-28 2000-03-02 Hans Juergen Pauling Wiederaufladbare Batterieanordnung und deren Verwendung
US20050281751A1 (en) 1997-07-21 2005-12-22 Bruce Levin Directed intranasal administration of pharmaceutical agents
US6093743A (en) 1998-06-23 2000-07-25 Medinox Inc. Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
US20030181495A1 (en) 1998-06-23 2003-09-25 Medinox, Inc. Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
US6596770B2 (en) 2000-05-05 2003-07-22 Medinox, Inc. Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
US6697361B2 (en) 1998-09-15 2004-02-24 Nortel Networks Limited Method and apparatus for stream aggregation in a multiprotocol label switching network environment
US6274627B1 (en) 1999-10-12 2001-08-14 Medinox, Inc. Conjugates of dithiocarbamate disulfides with pharmacologically active agents and uses therefor
WO2003009834A1 (en) 2000-08-17 2003-02-06 Battey Alyce S Oral delivery of pharmaceuticals via encapsulation
US20020045184A1 (en) * 2000-10-02 2002-04-18 Chih-Ming Chen Packaging system
WO2003032912A2 (en) 2001-10-16 2003-04-24 Hypnion, Inc. Treatment of cns disorders using cns target modulators
US7189757B2 (en) 2001-10-16 2007-03-13 Hypnion, Inc. Treatment of sleep disorders using CNS target modulators
GB0128674D0 (en) 2001-11-30 2002-01-23 Boots Co Plc Treatment of sleep disorders and the like
JP2005519073A (ja) 2002-01-18 2005-06-30 ヒプニオン， インコーポレイテッド 睡眠標的モジュレーターを使用する睡眠障害の治療
DE10223147A1 (de) * 2002-05-16 2003-11-27 Newfrey Llc Fügesystemkopf, Fügesystem und Verfahren zum Zuführen und Fügen von Elementen
US7790867B2 (en) 2002-12-05 2010-09-07 Rosetta Genomics Inc. Vaccinia virus-related nucleic acids and microRNA
US7863287B2 (en) * 2002-12-18 2011-01-04 Wyeth Llc Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
GB0312419D0 (en) 2003-05-30 2003-07-02 Boots Healthcare Int Ltd Use of a compound in the treatment of sleep disorders and the like, in providing refreshedness on waking and a method for the treatment of grogginess
GB0312425D0 (en) 2003-05-30 2003-07-09 Boots Co Plc Use of a compound in the treatment of sleep disorders and the like,in providing refreshedness on waking and a method for the treatment of grogginess therewith
US20070292498A1 (en) 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US20110053999A1 (en) 2004-03-03 2011-03-03 Daley Thomas E 4-methylpyrazole formulations for inhibiting ethanol intolerance
WO2005084392A2 (en) * 2004-03-03 2005-09-15 Convivia 4-methylpyrazole formulations for inhibiting ethanol intolerance
GB2435410B (en) * 2004-04-21 2007-12-05 Silent Gliss Internat Ltd Improvements in or relating to curtain heading systems
EP1782831B1 (en) 2004-08-18 2011-10-19 Medrx Co., Ltd. External preparation
JP5049129B2 (ja) 2004-09-21 2012-10-17 ハイプニオン・インコーポレイテッド ロキサピン類縁体およびそれらの使用方法
US20060063754A1 (en) 2004-09-21 2006-03-23 Edgar Dale M Methods of treating a sleep disorder
WO2006049734A2 (en) 2004-10-29 2006-05-11 Hypnion, Inc. Quetiapine analogs and methods of use thereof
ES2416679T3 (es) 2004-12-15 2013-08-02 Nipro Patch Co., Ltd. Preparación de cinta médica
US10016385B2 (en) 2004-12-17 2018-07-10 Alan B. Cash Method for extending lifespan delaying the onset of age-related disease
CN101123948A (zh) 2005-02-17 2008-02-13 千寿制药株式会社 眼科用固体外用药剂
US20070093520A1 (en) 2005-04-15 2007-04-26 Caras Steven D Method of treatment of diarrhea-predominant irritable bowel syndrome in a subject
US20070086974A1 (en) * 2005-10-06 2007-04-19 Gawande Rahul S Cetirizine compositions
US20070196518A1 (en) 2005-12-15 2007-08-23 Karol Wojewnik Composition and Method for Mitigating a Negative Effect of Alcohol Consumption
WO2007092334A1 (en) 2006-02-02 2007-08-16 Hypnion, Inc. Method of treating sleep disorders
WO2007092333A1 (en) 2006-02-03 2007-08-16 Hypnion, Inc. Use of olopatadine for treating sleep disorders
JP2009529673A (ja) 2006-03-07 2009-08-20 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インク． 服薬遵守モニターシステム
US20080131532A1 (en) 2006-10-17 2008-06-05 Lorn Leitman Fast asleep
CA2673481A1 (en) 2006-12-19 2008-06-26 University Of Virginia Patent Foundation Combined effects of topiramate and ondansetron on alcohol consumption
CA2677205A1 (en) 2007-01-31 2008-08-07 University Of Virginia Patent Foundation Topiramate plus naltrexone for the treatment of addictive disorders
US20110065628A1 (en) 2007-08-27 2011-03-17 University Of Virginia Patent Foundation Medication Combinations for the Treatment of Alcoholism and Drug Addiction
US20090156982A1 (en) 2007-09-06 2009-06-18 Arezou Petrie Transdermal treatment device and method
EP2214478A1 (en) 2007-10-19 2010-08-11 Innozen, Inc. Composition for administering an active ingredient and method for making and using the same
NZ587202A (en) * 2008-01-04 2013-03-28 Schabar Res Associates Llc Methods for measuring a patient response upon administration of a drug and compositions thereof
US8440632B2 (en) * 2008-01-24 2013-05-14 Raptor Therapeutics Inc. Protopanaxadiol-type ginsenoside compositions and uses thereof
US20090258869A1 (en) 2008-02-08 2009-10-15 The Regents Of The University Of California Methods and compounds for treatment or prevention of substance-related disorders
CA2716498C (en) 2008-02-28 2020-12-22 University Of Virginia Patent Foundation Serotonin transporter gene and treatment of alcoholism
US8618157B2 (en) 2008-06-20 2013-12-31 Alphapharm Pty. Ltd. Pharmaceutical formulation
CA2767646C (en) 2009-07-10 2019-01-29 President And Fellows Of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
WO2011006066A1 (en) 2009-07-10 2011-01-13 Ironwood Pharmaceuticals, Inc. Cb receptor agonists
US20130109721A1 (en) 2009-12-08 2013-05-02 Ironwood Pharmaceuticals, Inc. FAAH Inhibitors
WO2011075688A1 (en) 2009-12-18 2011-06-23 Exodos Life Sciences Limited Partnership Methods and compositions for treating and preventing trigeminal autonomic cephalgias, migraine, and vascular conditions
WO2011100359A1 (en) 2010-02-09 2011-08-18 Ironwood Pharmaceuticals, Inc. Cannabinoid agonists
WO2011100324A1 (en) 2010-02-09 2011-08-18 Ironwood Pharmaceuticals Inc. Cannabinoid receptor agonists
WO2012048294A2 (en) 2010-10-07 2012-04-12 Trinity Laboratories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen
WO2012088431A1 (en) 2010-12-23 2012-06-28 Ironwood Pharmaceuticals, Inc. Faah inhibitors
CN103491951A (zh) 2011-02-28 2014-01-01 赫洛罗斯技术股份有限公司 用于口吸收的可咀嚼媒介物
CN103702685B (zh) 2011-05-20 2017-12-15 奥尔德生物控股有限责任公司 抗cgrp抗体和抗体片段用于在有需要的受试者、尤其是偏头痛患者中预防或抑制畏光或厌光的用途
US9161957B2 (en) 2012-08-03 2015-10-20 Life Well Lived, Llc Compositions and methods for reducing blood alcohol content
JP6276944B2 (ja) * 2013-08-29 2018-02-07 興和株式会社 フェキソフェナジンとｎｓａｉｄ含有医薬組成物
BR112017020307B1 (pt) * 2015-03-26 2023-11-07 Jacqueline M. Iversen Usos de uma combinação de naproxeno e fexofenadina
WO2019178516A1 (en) * 2018-03-16 2019-09-19 SEN-JAM Pharmaceutical LLC Methods and compositions to treat enteropathic arthritis

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053396A (en) * 1985-08-27 1991-10-01 Blass David H Therapeutic composition
US4975426A (en) * 1987-06-08 1990-12-04 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
WO1992005783A1 (en) * 1990-09-28 1992-04-16 Merck & Co., Inc. Ibuprofen-antihistamine combinations
WO1999015173A1 (en) * 1997-09-19 1999-04-01 The Procter & Gamble Company Compositions and methods for treating respiratory disorders
US20050203105A1 (en) * 2002-08-15 2005-09-15 Tan Oon T. Composition and method for controlling alcohol-induced facial flushing in susceptible humans
US20040253311A1 (en) * 2002-12-18 2004-12-16 Roger Berlin Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines
GB2435418A (en) * 2006-02-28 2007-08-29 Amalan Selvarajah Composition for preventing and alleviating alcohol hangover
US20080113021A1 (en) * 2006-10-25 2008-05-15 Robert Shen Ibuprofen composition
US20090306025A1 (en) * 2008-05-30 2009-12-10 Fairfield Clinical Trials, Llc Method and composition for skin inflammation and discoloration
WO2015073573A1 (en) * 2013-11-14 2015-05-21 Jacobs Michael M Compositions and methods for the prevention and treatment of alcohol-induced hangover syndrome

Also Published As

Publication number Publication date
PL3273952T3 (pl) 2022-11-14
JP6851365B2 (ja) 2021-03-31
MX390011B (es) 2025-03-20
CA2980162C (en) 2024-06-18
JP2018509470A (ja) 2018-04-05
ZA201706794B (en) 2019-02-27
EP3273952B1 (en) 2022-06-15
US20160279112A1 (en) 2016-09-29
MX2022001796A (es) 2022-03-17
KR20170131647A (ko) 2017-11-29
IL254641B1 (en) 2023-09-01
US20200009119A1 (en) 2020-01-09
EP3973957A1 (en) 2022-03-30
IL254641B2 (en) 2024-01-01
CA2980162A1 (en) 2016-09-29
ES2926494T3 (es) 2022-10-26
US10420756B2 (en) 2019-09-24
KR102597910B1 (ko) 2023-11-02
BR112017020307A2 (pt) 2018-06-05
BR112017020307B1 (pt) 2023-11-07
IL254641A0 (en) 2017-11-30
AU2016235484A1 (en) 2017-10-12
MX2017012132A (es) 2018-07-06
CN115887456A (zh) 2023-04-04
WO2016154028A1 (en) 2016-09-29
CN107635549A (zh) 2018-01-26
NZ735777A (en) 2023-03-31
US20230064685A1 (en) 2023-03-02
US11464766B2 (en) 2022-10-11
EP3273952A4 (en) 2018-11-21
EP3273952A1 (en) 2018-01-31

Similar Documents

Publication Publication Date Title
US11464766B2 (en) Methods and compositions to inhibit symptoms associated with veisalgia
JP6556767B2 (ja) Ｄｐｐ−４阻害剤（リナグリプチン）を任意で他の抗糖尿病薬と組み合わせて含む抗糖尿病薬
TWI520738B (zh) Dpp-4抑制劑於已接受抗糖尿病藥物療法而血糖控制仍不足之患者之用途
TW201002718A (en) Treatment for NAFLD
TW201038272A (en) Treatment for diabetes in paediatric patients
US7834056B2 (en) Pharmaceutical composition for gout
TW201011027A (en) Treatment for diabetes in patients inappropriate for metformin therapy
JP2016518438A (ja) ＤＰＰ−４阻害薬とα−グルコシダーゼ阻害薬との組合せ
US20250319069A1 (en) Methods for treating depressive states
US20240115559A1 (en) Methods and Compositions to Inhibit Symptoms Associated with Viral Upper Respiratory Tract Infections
TW200534852A (en) 4-methylpyrazole formulations for inhibiting ethanol intolerance
US8058296B2 (en) Treatment and prevention of deleterious effects associated with alcohol consumption
Sotoyama et al. Ease of taking and palatability of fixed-dose orally disintegrating mitiglinide/voglibose tablets
US20050203105A1 (en) Composition and method for controlling alcohol-induced facial flushing in susceptible humans
JP2009501795A (ja) 高尿酸血に関連する健康状態の治療及び予防のための組成物及び方法
CN117750956A (zh) 用于治疗抑郁状态的方法
JP2006524647A (ja) アルコール乱用治療のためのデオキシペガニンとメカミルアミンの組合せ
JP2023548380A (ja) 非水溶性ｃｏｘ－２阻害の水性製剤

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)