AU2015374467A1 - Use of 2-methylene-19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism - Google Patents
Use of 2-methylene-19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism Download PDFInfo
- Publication number
- AU2015374467A1 AU2015374467A1 AU2015374467A AU2015374467A AU2015374467A1 AU 2015374467 A1 AU2015374467 A1 AU 2015374467A1 AU 2015374467 A AU2015374467 A AU 2015374467A AU 2015374467 A AU2015374467 A AU 2015374467A AU 2015374467 A1 AU2015374467 A1 AU 2015374467A1
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- Australia
- Prior art keywords
- primary hyperparathyroidism
- subject
- symptoms
- therapeutically effective
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462098119P | 2014-12-30 | 2014-12-30 | |
| US62/098,119 | 2014-12-30 | ||
| US14/710,744 US10369161B2 (en) | 2014-12-30 | 2015-05-13 | Use of 2-methylene-19-NOR-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism |
| US14/710,744 | 2015-05-13 | ||
| PCT/US2015/065174 WO2016109155A1 (en) | 2014-12-30 | 2015-12-11 | USE OF 2-METHYLENE-19-NOR-(20S)-1α,25-DIHYDROXYVITAMIN D3 TO TREAT PRIMARY HYPERPARATHYROIDISM |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2015374467A1 true AU2015374467A1 (en) | 2017-06-15 |
Family
ID=56162989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2015374467A Abandoned AU2015374467A1 (en) | 2014-12-30 | 2015-12-11 | Use of 2-methylene-19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10369161B2 (https=) |
| EP (1) | EP3240548A1 (https=) |
| JP (1) | JP2018500373A (https=) |
| AU (1) | AU2015374467A1 (https=) |
| CA (1) | CA2969335A1 (https=) |
| WO (1) | WO2016109155A1 (https=) |
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| US20040043971A1 (en) | 1995-04-03 | 2004-03-04 | Bone Care International, Inc. | Method of treating and preventing hyperparathyroidism with active vitamin D analogs |
| US6242434B1 (en) * | 1997-08-08 | 2001-06-05 | Bone Care International, Inc. | 24-hydroxyvitamin D, analogs and uses thereof |
| US5843928A (en) | 1997-03-17 | 1998-12-01 | Wisconsin Alumni Research Foundation | 2-alkylidene-19-nor-vitamin D compounds |
| US6306844B1 (en) | 1997-03-17 | 2001-10-23 | Wisconsin Alumni Research Foundation | Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength |
| US6136799A (en) | 1998-04-08 | 2000-10-24 | Abbott Laboratories | Cosolvent formulations |
| US6673782B2 (en) | 1999-04-29 | 2004-01-06 | Wisconsin Alumni Research Foundation | Treatment of systemic lupus erythematosis |
| JP2003528833A (ja) | 2000-03-27 | 2003-09-30 | ウイスコンシン アラムナイ リサーチ フオンデーシヨン | 腎移植体安定化用のビタミンｄ化合物 |
| MXPA03000406A (es) | 2000-07-14 | 2003-06-06 | Wisconsin Alumni Res Found | Uso de 2-metilen-19-nor-20(s)-1 alfa,25-dihidroxivitamina d3 para incrementar la resistencia de los huesos. |
| US20050124591A1 (en) | 2003-07-29 | 2005-06-09 | Jin Tian | Use of vitamin Ds to treat kidney disease |
| US20060171983A1 (en) | 2003-07-30 | 2006-08-03 | Jin Tian | Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease |
| US7704980B2 (en) | 2003-10-08 | 2010-04-27 | Wisconsin Alumni Research Foundation | Treatment of inflammatory bowel disease with 2-methylene-19-nor-vitamin D compounds |
| US7214671B2 (en) | 2004-02-19 | 2007-05-08 | Wisconsin Alumni Research Foundation | Use of 2-methylene-19-nor-20(S)-1α,25-dihydroxyvitamin D3 for the prophylaxis of bone diseases |
| WO2006086613A2 (en) | 2005-02-11 | 2006-08-17 | Wisconsin Alumni Research Foundation | 2-METHYLENE-19-NOR- (20S-24S) - 1α, 25-D IHYDROXYVITAMIN-D2 |
| AU2010281391B2 (en) | 2009-08-03 | 2015-05-07 | Wisconsin Alumni Research Foundation | Method of preventing renal disease and treating symptoms thereof |
| US8604009B2 (en) | 2010-03-23 | 2013-12-10 | Wisconsin Alumni Research Foundation | (20S)-2-methylene-19-nor-22-dimethyl-1α,25-dihydroxyvitamin D3 and (20R)-2-methylene-19-nor-22-dimethyl-1α,25-hydroxyvitamin D3 |
| CN104394871A (zh) | 2012-06-29 | 2015-03-04 | 威斯康星旧生研究基金会 | 2-亚甲基-19-去甲-(20S)-1α,25-二羟基维生素D3治疗继发性甲状旁腺功能亢进的用途 |
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2015
- 2015-05-13 US US14/710,744 patent/US10369161B2/en not_active Expired - Fee Related
- 2015-12-11 EP EP15817706.3A patent/EP3240548A1/en not_active Withdrawn
- 2015-12-11 WO PCT/US2015/065174 patent/WO2016109155A1/en not_active Ceased
- 2015-12-11 CA CA2969335A patent/CA2969335A1/en not_active Abandoned
- 2015-12-11 JP JP2017534936A patent/JP2018500373A/ja active Pending
- 2015-12-11 AU AU2015374467A patent/AU2015374467A1/en not_active Abandoned
Also Published As
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| US20160184327A1 (en) | 2016-06-30 |
| CA2969335A1 (en) | 2016-07-07 |
| US10369161B2 (en) | 2019-08-06 |
| JP2018500373A (ja) | 2018-01-11 |
| WO2016109155A1 (en) | 2016-07-07 |
| EP3240548A1 (en) | 2017-11-08 |
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