AU2015259004B2 - Low-power miniature LED-based UV absorption detector with low detection limits for capillary liquid chromatography - Google Patents

Low-power miniature LED-based UV absorption detector with low detection limits for capillary liquid chromatography Download PDF

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Publication number
AU2015259004B2
AU2015259004B2 AU2015259004A AU2015259004A AU2015259004B2 AU 2015259004 B2 AU2015259004 B2 AU 2015259004B2 AU 2015259004 A AU2015259004 A AU 2015259004A AU 2015259004 A AU2015259004 A AU 2015259004A AU 2015259004 B2 AU2015259004 B2 AU 2015259004B2
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Australia
Prior art keywords
light
capillary column
detector
led
lens
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AU2015259004A
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English (en)
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AU2015259004A1 (en
Inventor
Paul B. Farnsworth
Milton L. Lee
Sonika SHARMA
H. Dennis Tolley
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Brigham Young University
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Brigham Young University
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/022—Casings
    • G01N2201/0221—Portable; cableless; compact; hand-held
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0621—Supply
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/069—Supply of sources
    • G01N2201/0693—Battery powered circuitry

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  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AU2015259004A 2014-05-15 2015-05-15 Low-power miniature LED-based UV absorption detector with low detection limits for capillary liquid chromatography Active AU2015259004B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461996803P 2014-05-15 2014-05-15
US61/996,803 2014-05-15
PCT/US2015/031023 WO2015175906A1 (en) 2014-05-15 2015-05-15 Low-power miniature led-based uv absorption detector with low detection limits for capillary liquid chromatography

Publications (2)

Publication Number Publication Date
AU2015259004A1 AU2015259004A1 (en) 2016-12-01
AU2015259004B2 true AU2015259004B2 (en) 2018-11-08

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Family Applications (1)

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AU2015259004A Active AU2015259004B2 (en) 2014-05-15 2015-05-15 Low-power miniature LED-based UV absorption detector with low detection limits for capillary liquid chromatography

Country Status (7)

Country Link
US (1) US10060889B2 (enExample)
EP (1) EP3142765B1 (enExample)
JP (1) JP6804436B2 (enExample)
CN (1) CN106536011B (enExample)
AU (1) AU2015259004B2 (enExample)
CA (1) CA2949213C (enExample)
WO (1) WO2015175906A1 (enExample)

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AT518576B1 (de) * 2016-04-18 2018-07-15 Scan Messtechnik Gmbh Spektrometer
NL2019122A (en) * 2016-06-30 2018-01-09 Asml Holding Nv Adaptive filter for in-line correction
WO2018161090A1 (en) * 2017-03-03 2018-09-07 Brigham Young University Multi-modal, multi-detector liquid chromatographic system
CA3063957A1 (en) * 2017-05-18 2018-11-22 Brigham Young University Combined fluorescence and absorption detector for on-column detection after capillary separation techniques
CN108562540A (zh) * 2017-12-29 2018-09-21 深圳市华星光电技术有限公司 光学测试装置
JP7074305B2 (ja) * 2018-06-01 2022-05-24 アクアモニトリックス リミテッド 無機分析物を検出するための光学検出セルおよびシステム
US11982620B2 (en) * 2019-03-18 2024-05-14 Life Technologies Corporation Multi-capillary optical detection system
JP7235298B2 (ja) * 2019-03-20 2023-03-08 株式会社日立ハイテクサイエンス クロマトグラフのデータ処理装置、データ処理方法、およびクロマトグラフ
CN110047519B (zh) * 2019-04-16 2021-08-24 广州大学 一种语音端点检测方法、装置及设备
JP7739421B2 (ja) * 2020-09-22 2025-09-16 ベクトン・ディキンソン・アンド・カンパニー フローサイトメータにおけるベースラインノイズの連続測定方法およびそのためのシステム
CN115684446A (zh) * 2022-09-28 2023-02-03 上海交通大学 等电聚焦毛细管结构、毛细管盒、全柱成像装置
US20250321209A1 (en) * 2024-04-16 2025-10-16 Vuv Analytics, Inc. Spectroscopy Systems, Flow Cells And Methods For Analyzing Liquids At Vacuum Ultraviolet (VUV) Wavelengths

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US20060019265A1 (en) * 2004-04-30 2006-01-26 Kimberly-Clark Worldwide, Inc. Transmission-based luminescent detection systems
US20080013092A1 (en) * 2006-05-19 2008-01-17 George Maltezos Fluorescence detector, filter device and related methods

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JPH04115084U (ja) * 1991-03-26 1992-10-12 九州電機製造株式会社 電気自動車用電池残存容量計
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US20030110840A1 (en) * 2001-07-24 2003-06-19 Arriaga Edgar A. Systems and methods for detecting a particle
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Patent Citations (2)

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US20060019265A1 (en) * 2004-04-30 2006-01-26 Kimberly-Clark Worldwide, Inc. Transmission-based luminescent detection systems
US20080013092A1 (en) * 2006-05-19 2008-01-17 George Maltezos Fluorescence detector, filter device and related methods

Also Published As

Publication number Publication date
JP6804436B2 (ja) 2020-12-23
EP3142765B1 (en) 2019-08-14
JP2017516120A (ja) 2017-06-15
US20150330955A1 (en) 2015-11-19
CN106536011A (zh) 2017-03-22
WO2015175906A1 (en) 2015-11-19
AU2015259004A1 (en) 2016-12-01
CA2949213A1 (en) 2015-11-19
CA2949213C (en) 2022-07-12
US10060889B2 (en) 2018-08-28
EP3142765A1 (en) 2017-03-22
CN106536011B (zh) 2019-08-20
EP3142765A4 (en) 2018-01-17

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