AU2015237933B2 - Expression of a single chain antibody against Salmonella in Lactobacillus - Google Patents

Expression of a single chain antibody against Salmonella in Lactobacillus Download PDF

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AU2015237933B2
AU2015237933B2 AU2015237933A AU2015237933A AU2015237933B2 AU 2015237933 B2 AU2015237933 B2 AU 2015237933B2 AU 2015237933 A AU2015237933 A AU 2015237933A AU 2015237933 A AU2015237933 A AU 2015237933A AU 2015237933 B2 AU2015237933 B2 AU 2015237933B2
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AU2015237933A1 (en
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Sanjiban Kumar BANERJEE
Sambuddha GHOSH
Manisha Pravin SABNIS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1228—Enterobacterales (O), e.g. Citrobacter (G), Serratia (G), Proteus (G), Providencia (G), Morganella (G) or Yersinia (G)
    • C07K16/1235—Salmonella (G)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/335—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Lactobacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2015237933A 2014-03-27 2015-03-27 Expression of a single chain antibody against Salmonella in Lactobacillus Active AU2015237933B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1100/MUM/2014 2014-03-27
IN1100MU2014 IN2014MU01100A (https=) 2014-03-27 2015-03-27
PCT/IB2015/000407 WO2015145250A2 (en) 2014-03-27 2015-03-27 Expression of a single chain antibody against salmonella in lactobacillus

Publications (2)

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AU2015237933A1 AU2015237933A1 (en) 2016-10-20
AU2015237933B2 true AU2015237933B2 (en) 2020-09-17

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AU2015237933A Active AU2015237933B2 (en) 2014-03-27 2015-03-27 Expression of a single chain antibody against Salmonella in Lactobacillus

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US (1) US10544208B2 (https=)
EP (1) EP3122773B1 (https=)
CN (1) CN107074934B (https=)
AU (1) AU2015237933B2 (https=)
CA (1) CA2943903C (https=)
IN (1) IN2014MU01100A (https=)
MX (1) MX380349B (https=)
MY (1) MY199990A (https=)
WO (1) WO2015145250A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3122773B1 (en) 2014-03-27 2020-07-22 Ghosh, Sambuddha Expression of a single chain antibody against salmonella in lactobacillus
JP2018511303A (ja) * 2015-02-04 2018-04-26 アブセレックス テクノロジーズ インコーポレイテッド 抗サルモネラ抗体及びその使用
US11130800B2 (en) 2016-05-20 2021-09-28 Novobind Livestock Therapeutics Inc. Antibodies against microorganisms and uses thereof
MX2020013248A (es) * 2018-06-05 2021-04-13 Novobind Livestock Therapeutics Inc Anticuerpos contra agentes patogenos en acuacultura y sus aplicaciones.
CN108864281B (zh) * 2018-07-13 2020-09-08 西北农林科技大学 一种抗肠炎沙门氏菌的纳米抗体及其应用
US12195500B2 (en) 2018-11-13 2025-01-14 Novobind Livestock Therapeutics, Inc. Antibodies against disease causing agents of canines and felines and uses thereof
US20230309601A1 (en) * 2020-07-06 2023-10-05 Singapore University Of Technology And Design 3d printing of milk-based product
CN113564095B (zh) * 2021-07-27 2023-10-20 陈玉松 外源核苷酸在促进干酪乳杆菌拮抗肠沙门氏菌方面的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010029293A1 (en) * 2008-09-09 2010-03-18 The University Of Birmingham Non-typhoidal salmonella vaccines

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
US6100388A (en) 1998-03-16 2000-08-08 Biogaia Biologies Ab Lactobacilli harboring aggregation gene as a vaccine delivery vehicle
ATE556596T1 (de) * 2002-04-15 2012-05-15 Univ St Louis Regulierte attenuierung von lebendimpfstoffen zur verbesserung der kreuzimmunitätsschutzfunktion
MX2007006086A (es) 2004-11-25 2007-07-11 Unilever Nv Anticuerpos de cadena pesada y de dominio.
EP1915174A1 (en) 2005-08-19 2008-04-30 Unilever N.V. Food products comprising probiotic micro-organisms and antibodies
CN101469333B (zh) * 2007-12-25 2014-01-22 温州医学院 一种抗沙门菌单链抗体与跨膜蛋白融合蛋白的制备方法
EP3122773B1 (en) 2014-03-27 2020-07-22 Ghosh, Sambuddha Expression of a single chain antibody against salmonella in lactobacillus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010029293A1 (en) * 2008-09-09 2010-03-18 The University Of Birmingham Non-typhoidal salmonella vaccines

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EL KHATTABI, Mohamed et al., Llama single-chain antibody that blocks lipopolysaccharide binding and signaling: Prospects for therapeutic applications", CLINICAL AND VACCINE IMMUNOLOGY, October 2006, Vol 13 No 10 pages 1079-1086. *
GIL-CRUZ, Cristina et al., The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1 b cell antibody response. PNAS, 16 June 2009, vol. 106, no. 24, pages 9803-9808 *
WESOLOWSKI, Janusz et al., Single domain antibodies: promising experimental and therapeutic tools in infection and immunity. MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 16 June 2009, vol. 198, no. 3, pages 157-174 *

Also Published As

Publication number Publication date
MX380349B (es) 2025-03-12
EP3122773B1 (en) 2020-07-22
MY199990A (en) 2023-12-02
EP3122773A2 (en) 2017-02-01
BR112016022375A2 (pt) 2019-01-15
CA2943903C (en) 2023-03-14
US10544208B2 (en) 2020-01-28
CN107074934B (zh) 2021-06-29
CN107074934A (zh) 2017-08-18
NZ725349A (en) 2024-05-31
WO2015145250A2 (en) 2015-10-01
WO2015145250A3 (en) 2016-01-21
IN2014MU01100A (https=) 2015-10-02
AU2015237933A1 (en) 2016-10-20
MX2016012597A (es) 2017-04-27
CA2943903A1 (en) 2015-10-01
US20170152305A1 (en) 2017-06-01

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