AU2014228596A1 - Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom - Google Patents
Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom Download PDFInfo
- Publication number
- AU2014228596A1 AU2014228596A1 AU2014228596A AU2014228596A AU2014228596A1 AU 2014228596 A1 AU2014228596 A1 AU 2014228596A1 AU 2014228596 A AU2014228596 A AU 2014228596A AU 2014228596 A AU2014228596 A AU 2014228596A AU 2014228596 A1 AU2014228596 A1 AU 2014228596A1
- Authority
- AU
- Australia
- Prior art keywords
- valve
- leaflet
- composite material
- less
- fluoropolymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000002131 composite material Substances 0.000 title claims abstract description 200
- 239000007943 implant Substances 0.000 title abstract description 8
- 229920000642 polymer Polymers 0.000 title description 20
- 229920002313 fluoropolymer Polymers 0.000 claims abstract description 170
- 239000004811 fluoropolymer Substances 0.000 claims abstract description 170
- 239000011148 porous material Substances 0.000 claims abstract description 109
- 229920001971 elastomer Polymers 0.000 claims abstract description 93
- 239000000806 elastomer Substances 0.000 claims abstract description 93
- 238000000034 method Methods 0.000 claims description 56
- 229920001973 fluoroelastomer Polymers 0.000 claims description 31
- 229920001577 copolymer Polymers 0.000 claims description 16
- 230000017531 blood circulation Effects 0.000 claims description 14
- 238000005452 bending Methods 0.000 claims description 11
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 claims description 10
- BLTXWCKMNMYXEA-UHFFFAOYSA-N 1,1,2-trifluoro-2-(trifluoromethoxy)ethene Chemical compound FC(F)=C(F)OC(F)(F)F BLTXWCKMNMYXEA-UHFFFAOYSA-N 0.000 claims description 9
- 230000001105 regulatory effect Effects 0.000 claims description 6
- JOYRKODLDBILNP-UHFFFAOYSA-N urethane group Chemical group NC(=O)OCC JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 claims 4
- 210000003709 heart valve Anatomy 0.000 abstract description 35
- 238000011049 filling Methods 0.000 abstract description 9
- 239000010410 layer Substances 0.000 description 230
- 239000012528 membrane Substances 0.000 description 130
- 239000000463 material Substances 0.000 description 78
- 238000012360 testing method Methods 0.000 description 38
- 239000004812 Fluorinated ethylene propylene Substances 0.000 description 31
- 239000000835 fiber Substances 0.000 description 31
- 229920009441 perflouroethylene propylene Polymers 0.000 description 31
- 230000006835 compression Effects 0.000 description 28
- 238000007906 compression Methods 0.000 description 28
- 239000011159 matrix material Substances 0.000 description 27
- 239000000523 sample Substances 0.000 description 22
- 229920001296 polysiloxane Polymers 0.000 description 20
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 20
- 239000004810 polytetrafluoroethylene Substances 0.000 description 20
- 238000000576 coating method Methods 0.000 description 17
- 230000008569 process Effects 0.000 description 17
- 239000011248 coating agent Substances 0.000 description 16
- 230000015572 biosynthetic process Effects 0.000 description 15
- 239000010408 film Substances 0.000 description 13
- 238000009958 sewing Methods 0.000 description 13
- 230000001965 increasing effect Effects 0.000 description 12
- 238000005259 measurement Methods 0.000 description 12
- 230000000712 assembly Effects 0.000 description 9
- 238000000429 assembly Methods 0.000 description 9
- 230000015556 catabolic process Effects 0.000 description 9
- 238000006731 degradation reaction Methods 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 8
- 229920001169 thermoplastic Polymers 0.000 description 8
- 238000010276 construction Methods 0.000 description 7
- 239000004416 thermosoftening plastic Substances 0.000 description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 238000000465 moulding Methods 0.000 description 6
- 229920003223 poly(pyromellitimide-1,4-diphenyl ether) Polymers 0.000 description 6
- -1 polytetrafluoroethylene Polymers 0.000 description 6
- 230000002829 reductive effect Effects 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 238000012512 characterization method Methods 0.000 description 5
- 239000013536 elastomeric material Substances 0.000 description 5
- 239000007789 gas Substances 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 230000037303 wrinkles Effects 0.000 description 5
- 229910000619 316 stainless steel Inorganic materials 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 230000003466 anti-cipated effect Effects 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 238000005520 cutting process Methods 0.000 description 4
- 125000004122 cyclic group Chemical group 0.000 description 4
- 230000032798 delamination Effects 0.000 description 4
- 239000001307 helium Substances 0.000 description 4
- 229910052734 helium Inorganic materials 0.000 description 4
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 4
- 229910052742 iron Inorganic materials 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 229920001721 polyimide Polymers 0.000 description 4
- 239000002356 single layer Substances 0.000 description 4
- 238000005476 soldering Methods 0.000 description 4
- 238000001179 sorption measurement Methods 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 238000007669 thermal treatment Methods 0.000 description 4
- 230000000007 visual effect Effects 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 230000000004 hemodynamic effect Effects 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 238000009832 plasma treatment Methods 0.000 description 3
- 238000010791 quenching Methods 0.000 description 3
- 238000001878 scanning electron micrograph Methods 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000004642 Polyimide Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 239000002156 adsorbate Substances 0.000 description 2
- 230000004075 alteration Effects 0.000 description 2
- 239000012298 atmosphere Substances 0.000 description 2
- 230000002308 calcification Effects 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000006082 mold release agent Substances 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 229920005597 polymer membrane Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 230000002685 pulmonary effect Effects 0.000 description 2
- 210000003102 pulmonary valve Anatomy 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 238000005096 rolling process Methods 0.000 description 2
- 229920002379 silicone rubber Polymers 0.000 description 2
- 239000004945 silicone rubber Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- ZSDSQXJSNMTJDA-UHFFFAOYSA-N trifluralin Chemical compound CCCN(CCC)C1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C1[N+]([O-])=O ZSDSQXJSNMTJDA-UHFFFAOYSA-N 0.000 description 2
- 230000002861 ventricular Effects 0.000 description 2
- 238000004804 winding Methods 0.000 description 2
- 238000012935 Averaging Methods 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 229910000684 Cobalt-chrome Inorganic materials 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 239000004687 Nylon copolymer Substances 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- WAIPAZQMEIHHTJ-UHFFFAOYSA-N [Cr].[Co] Chemical compound [Cr].[Co] WAIPAZQMEIHHTJ-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 229920000249 biocompatible polymer Polymers 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 239000010952 cobalt-chrome Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 230000035487 diastolic blood pressure Effects 0.000 description 1
- 230000003205 diastolic effect Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000003028 elevating effect Effects 0.000 description 1
- FHTQCUNSKSWOHF-UHFFFAOYSA-N ethyl carbamate;silicon Chemical compound [Si].CCOC(N)=O FHTQCUNSKSWOHF-UHFFFAOYSA-N 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000009661 fatigue test Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 210000003090 iliac artery Anatomy 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000011256 inorganic filler Substances 0.000 description 1
- 229910003475 inorganic filler Inorganic materials 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000001000 micrograph Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000013001 point bending Methods 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 238000004382 potting Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 210000001147 pulmonary artery Anatomy 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 238000007788 roughening Methods 0.000 description 1
- 238000004626 scanning electron microscopy Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 238000009864 tensile test Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 238000009966 trimming Methods 0.000 description 1
- 150000003673 urethanes Chemical class 0.000 description 1
- 210000001631 vena cava inferior Anatomy 0.000 description 1
- 210000002073 venous valve Anatomy 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/801,701 | 2013-03-13 | ||
US13/801,701 US20130197631A1 (en) | 2011-04-01 | 2013-03-13 | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
PCT/US2014/016581 WO2014143498A1 (en) | 2013-03-13 | 2014-02-14 | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2014228596A1 true AU2014228596A1 (en) | 2015-09-10 |
Family
ID=50193614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2014228596A Abandoned AU2014228596A1 (en) | 2013-03-13 | 2014-02-14 | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP2968675A1 (ja) |
JP (1) | JP2016514011A (ja) |
KR (1) | KR20150127222A (ja) |
CN (1) | CN105188788A (ja) |
AU (1) | AU2014228596A1 (ja) |
CA (1) | CA2902814A1 (ja) |
HK (1) | HK1216086A1 (ja) |
WO (1) | WO2014143498A1 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20190290800A1 (en) | 2016-03-17 | 2019-09-26 | Centro Cardiologico Monzino | Polymers and uses thereof in manufacturing of 'living' heart valves |
EP4364696A3 (en) * | 2017-09-27 | 2024-07-03 | Edwards Lifesciences Corporation | Prosthetic valve with expandable frame and associated systems and methods |
JP2021500963A (ja) * | 2017-10-31 | 2021-01-14 | ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティドW.L. Gore & Associates, Incorporated | 合成人工弁弁尖 |
JP7317966B2 (ja) * | 2018-12-05 | 2023-07-31 | ゼルティス アーゲー | 電界紡糸製縫合リング |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA962021A (en) | 1970-05-21 | 1975-02-04 | Robert W. Gore | Porous products and process therefor |
DE69428056T2 (de) | 1994-09-02 | 2002-01-03 | Gore & Ass | Poröse polytetrafluorethylen zusammensetzungen |
US7049380B1 (en) | 1999-01-19 | 2006-05-23 | Gore Enterprise Holdings, Inc. | Thermoplastic copolymer of tetrafluoroethylene and perfluoromethyl vinyl ether and medical devices employing the copolymer |
US6541589B1 (en) | 2001-10-15 | 2003-04-01 | Gore Enterprise Holdings, Inc. | Tetrafluoroethylene copolymer |
US20040024448A1 (en) | 2002-08-05 | 2004-02-05 | Chang James W. | Thermoplastic fluoropolymer-coated medical devices |
US7531611B2 (en) | 2005-07-05 | 2009-05-12 | Gore Enterprise Holdings, Inc. | Copolymers of tetrafluoroethylene |
US7306729B2 (en) | 2005-07-18 | 2007-12-11 | Gore Enterprise Holdings, Inc. | Porous PTFE materials and articles produced therefrom |
US8961599B2 (en) * | 2011-04-01 | 2015-02-24 | W. L. Gore & Associates, Inc. | Durable high strength polymer composite suitable for implant and articles produced therefrom |
US8945212B2 (en) * | 2011-04-01 | 2015-02-03 | W. L. Gore & Associates, Inc. | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
-
2014
- 2014-02-14 WO PCT/US2014/016581 patent/WO2014143498A1/en active Application Filing
- 2014-02-14 KR KR1020157028305A patent/KR20150127222A/ko not_active Application Discontinuation
- 2014-02-14 CN CN201480014208.7A patent/CN105188788A/zh active Pending
- 2014-02-14 AU AU2014228596A patent/AU2014228596A1/en not_active Abandoned
- 2014-02-14 JP JP2016500269A patent/JP2016514011A/ja active Pending
- 2014-02-14 EP EP14707902.4A patent/EP2968675A1/en not_active Withdrawn
- 2014-02-14 CA CA2902814A patent/CA2902814A1/en not_active Abandoned
-
2016
- 2016-04-12 HK HK16104135.0A patent/HK1216086A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
CN105188788A (zh) | 2015-12-23 |
JP2016514011A (ja) | 2016-05-19 |
KR20150127222A (ko) | 2015-11-16 |
CA2902814A1 (en) | 2014-09-18 |
HK1216086A1 (zh) | 2016-10-14 |
WO2014143498A1 (en) | 2014-09-18 |
EP2968675A1 (en) | 2016-01-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10342658B2 (en) | Methods of making durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom | |
US10022219B2 (en) | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom | |
CA2900656C (en) | Durable high strength polymer composites suitable for implant and articles produced therefrom | |
CA2830355C (en) | Durable high strength polymer composite suitable for implant and articles produced therefrom | |
AU2014228596A1 (en) | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom | |
AU2018203416B2 (en) | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom | |
AU2020204354A1 (en) | Durable high strength polymer composite suitable for implant and articles produced therefrom |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE NAME OF THE INVENTOR TO READ BRUCHMAN, WILLIAM C.; HARTMAN, CODY L.; GASSLER, PAUL D. AND WALSH, PETER J. |
|
MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |