AU2014225365B2 - Targeting CD138 in cancer - Google Patents
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- AU2014225365B2 AU2014225365B2 AU2014225365A AU2014225365A AU2014225365B2 AU 2014225365 B2 AU2014225365 B2 AU 2014225365B2 AU 2014225365 A AU2014225365 A AU 2014225365A AU 2014225365 A AU2014225365 A AU 2014225365A AU 2014225365 B2 AU2014225365 B2 AU 2014225365B2
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| SG11201505858VA (en) | 2013-01-28 | 2015-09-29 | St Jude Childrens Res Hospital | A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease |
| SG11201608393TA (en) | 2014-04-10 | 2016-11-29 | Seattle Children S Hospital Dba Seattle Children S Res Inst | Transgene genetic tags and methods of use |
| EP3143134B1 (en) | 2014-05-15 | 2020-10-28 | National University of Singapore | Modified natural killer cells and uses thereof |
| MX2017000646A (es) | 2014-07-15 | 2017-04-27 | Juno Therapeutics Inc | Celulas geneticamente modificadas para terapia celular adoptiva. |
| BR112017001242A2 (pt) | 2014-07-21 | 2017-12-05 | Novartis Ag | tratamento de câncer usando um receptor antigênico quimérico a cd33 |
| WO2016014565A2 (en) | 2014-07-21 | 2016-01-28 | Novartis Ag | Treatment of cancer using humanized anti-bcma chimeric antigen receptor |
| UA123764C2 (uk) | 2014-09-15 | 2021-06-02 | МОЛМЕД СпА | Химерний рецептор антигену та його застосування при лікуванні пухлин, які експресують cd44 |
| AU2015330017A1 (en) * | 2014-10-07 | 2017-04-27 | Cellectis | Method for modulating car-induced immune cells activity |
| MA40318A (fr) * | 2014-11-05 | 2017-09-13 | Juno Therapeutics Inc | Procédés de transduction et de traitement de cellules |
| HRP20240357T1 (hr) | 2014-12-24 | 2024-06-07 | Autolus Limited | Stanica |
| US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| IL303543A (en) | 2015-02-18 | 2023-08-01 | Enlivex Therapeutics Rdo Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
| US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| AU2016219785B2 (en) | 2015-02-20 | 2021-10-28 | Ohio State Innovation Foundation | Bivalent antibody directed against NKG2D and tumor associated antigens |
| CA2978171A1 (en) * | 2015-03-10 | 2016-09-15 | J.H. Frederik Falkenburg | T-cell receptors directed against the preferentially expressed antigen of melanoma and uses thereof |
| WO2016164370A1 (en) * | 2015-04-06 | 2016-10-13 | Ohio State Innovation Foundation | Egfr-directed car therapy for glioblastoma |
| IL254817B2 (en) | 2015-04-08 | 2023-12-01 | Novartis Ag | Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell |
| CN108473957B (zh) | 2015-04-17 | 2024-07-16 | 诺华股份有限公司 | 改善嵌合抗原受体表达细胞的功效和扩增的方法 |
| JP6223630B2 (ja) * | 2015-04-17 | 2017-11-01 | 三菱電機株式会社 | 表示制御装置、表示システム、表示制御方法および表示制御プログラム |
| CN113106053A (zh) | 2015-04-21 | 2021-07-13 | 恩立夫克治疗有限责任公司 | 治疗性汇集的血液凋亡细胞制剂与其用途 |
| MA42895A (fr) * | 2015-07-15 | 2018-05-23 | Juno Therapeutics Inc | Cellules modifiées pour thérapie cellulaire adoptive |
| JP7146632B2 (ja) * | 2015-07-21 | 2022-10-04 | ノバルティス アーゲー | 免疫細胞の有効性および増大を改善する方法 |
| US11458167B2 (en) | 2015-08-07 | 2022-10-04 | Seattle Children's Hospital | Bispecific CAR T-cells for solid tumor targeting |
| JP7054924B2 (ja) * | 2015-09-23 | 2022-04-15 | サイトイミューン セラピューティクス， インコーポレイテッド | 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 |
| JP2018536436A (ja) | 2015-12-04 | 2018-12-13 | ノバルティス アーゲー | 免疫腫瘍学のための組成物および方法 |
| CA3010869A1 (en) * | 2016-01-15 | 2017-07-20 | Etubics Corporation | Methods and compositions for t-cell immunotherapy |
| EP3408297A2 (en) | 2016-01-29 | 2018-12-05 | Med Manor Organics, (P) Ltd | A chimeric antigen receptor specific to b-cell maturation antigen, a recombinant expression vector and a method thereof |
| EP3416661A4 (en) * | 2016-02-18 | 2020-03-04 | Enlivex Therapeutics Ltd. | COMBINATION OF IMMUNOTHERAPY AND CYTOKINE CONTROL THERAPY FOR THE TREATMENT OF CANCER |
| WO2017176525A1 (en) * | 2016-04-04 | 2017-10-12 | Promab Biotechnologies, Inc. | Car having replicated binding motifs in a co-stimulatory domain |
| US20190328783A1 (en) * | 2016-04-15 | 2019-10-31 | Cellectis | A method of engineering prodrug-specific hypersensitive t-cells for immunotherapy by gene expression |
| EP3429633B1 (en) | 2016-04-15 | 2021-02-24 | Cellectis | A method of engineering drug-specific hypersensitive t-cells for immunotherapy by gene inactivation |
| EP3523331A1 (en) | 2016-10-07 | 2019-08-14 | Novartis AG | Chimeric antigen receptors for the treatment of cancer |
| JP7291396B2 (ja) * | 2016-11-22 | 2023-06-15 | ティーシーアール２ セラピューティクス インク． | 融合タンパク質を用いたｔｃｒの再プログラミングのための組成物及び方法 |
| CA3044682A1 (en) | 2016-12-02 | 2018-06-07 | University Of Southern California | Synthetic immune receptors and methods of use thereof |
| KR20190114966A (ko) | 2016-12-09 | 2019-10-10 | 온키뮨 리미티드 | 조작된 자연 살해 세포 및 이의 용도 |
| CN110291200B (zh) | 2016-12-12 | 2024-05-14 | 西雅图儿童医院（Dba西雅图儿童研究所） | 对哺乳动物细胞中转基因表达的药剂配体诱导具有增大的灵敏度的嵌合转录因子变异体 |
| MX2019011272A (es) | 2017-03-22 | 2019-10-24 | Novartis Ag | Composiciones y metodos para inmunooncologia. |
| EP3601537A4 (en) | 2017-03-27 | 2021-01-13 | National University of Singapore | STIMULATING CELL LINES FOR EX VIVO EXPANSION AND ACTIVATION OF NATURAL KILLER CELLS |
| SG11201908492PA (en) | 2017-03-27 | 2019-10-30 | Nat Univ Singapore | Truncated nkg2d chimeric receptors and uses thereof in natural killer cell immunotherapy |
| CN107164412B (zh) * | 2017-06-30 | 2020-10-23 | 山东兴瑞生物科技有限公司 | 一种安全型抗cea嵌合抗原受体修饰t细胞的制备方法及其应用 |
| ES2949855T3 (es) | 2017-12-05 | 2023-10-03 | Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct | Linfocitos T que comprenden receptores antigénicos quiméricos anti-CD38 y ant-CD138 y los usos de los mismos |
| WO2019111250A1 (en) * | 2017-12-05 | 2019-06-13 | The Medical Research Infrastructure And Health Services Fund Of The Tel Aviv Medical Center | T-cells comprising two different chimeric antigen receptors and uses thereof |
| CN111801348A (zh) | 2018-02-09 | 2020-10-20 | 新加坡国立大学 | 活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途 |
| KR20200138741A (ko) | 2018-04-02 | 2020-12-10 | 내셔널 유니버시티 오브 싱가포르 | 면역 세포에서 발현되는 막-결합 항-사이토카인 비-신호전달 결합제를 이용한 인간 사이토카인의 중화 |
| AU2019284911A1 (en) | 2018-06-13 | 2020-12-17 | Novartis Ag | BCMA chimeric antigen receptors and uses thereof |
| JP7560882B2 (ja) | 2018-08-29 | 2024-10-03 | ナショナル ユニヴァーシティー オブ シンガポール | 遺伝子修飾免疫細胞の生存及び増加を特異的に刺激するための方法 |
| WO2020160217A1 (en) * | 2019-02-01 | 2020-08-06 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Microenvironment sensors to regulate engineered gene expression |
| GB201902277D0 (en) * | 2019-02-19 | 2019-04-03 | King S College London | Therapeutic agents |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | ANTI-CD19 CHEMERIC ANTIGEN RECEPTORS AND THEIR USE IN IMMUNOTHERAPY |
| JP7650809B2 (ja) * | 2019-03-06 | 2025-03-25 | レンティジェン・テクノロジー・インコーポレイテッド | 自己駆動型キメラ抗原受容体を用いてがんを処置するための組成物および方法 |
| CN111686128A (zh) * | 2019-03-12 | 2020-09-22 | 重庆精准生物技术有限公司 | 一种缺氧可调控的启动子在car-t中的应用 |
| EP3922721A4 (en) * | 2019-03-12 | 2023-01-11 | Chongqing Precision Biotech Company Limited | PROMOTER REGULATED BY HYPOXIA AND ITS APPLICATION |
| CN114945382A (zh) | 2019-11-26 | 2022-08-26 | 诺华股份有限公司 | Cd19和cd22嵌合抗原受体及其用途 |
| KR20220137882A (ko) * | 2019-12-05 | 2022-10-12 | 바이셀릭스, 인크. | 보편적 세포 요법을 위한 면역 회피 기작의 조절제 |
| WO2022072990A1 (en) * | 2020-09-30 | 2022-04-07 | Baylor College Of Medicine | Cytotoxic and costimulatory chimeric antigen receptors |
| BR112023022765A2 (pt) | 2021-05-05 | 2024-01-02 | Immatics Biotechnologies Gmbh | Proteínas de ligação ao antígeno que ligam especificamente o prame |
| WO2025250011A1 (en) | 2024-05-29 | 2025-12-04 | Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis | Treatment for cancer |
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| WO2009080829A1 (en) * | 2007-12-26 | 2009-07-02 | Biotest Ag | Agents targeting cd138 and uses thereof |
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| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
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| GB9810423D0 (en) * | 1998-05-15 | 1998-07-15 | Cancer Res Campaign Tech | Ionizing radiation or diathermy-switched gene therapy vectors and their use in antitumour therapy |
| US20070036773A1 (en) * | 2005-08-09 | 2007-02-15 | City Of Hope | Generation and application of universal T cells for B-ALL |
| JP2011507933A (ja) * | 2007-12-26 | 2011-03-10 | バイオテスト・アクチエンゲゼルシヤフト | 免疫複合体の細胞傷害性副作用の低減及び有効性の改善方法 |
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| DK2981607T3 (da) * | 2013-04-03 | 2020-11-16 | Memorial Sloan Kettering Cancer Center | Effektiv generering af tumormålrettede t-celler afledt af pluripotente stamceller |
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- 2014-03-07 EP EP18190029.1A patent/EP3456818B1/en not_active Not-in-force
- 2014-03-07 CN CN201480026310.9A patent/CN105339498A/zh active Pending
- 2014-03-07 ES ES14719888.1T patent/ES2671004T3/es active Active
- 2014-03-07 CA CA2904369A patent/CA2904369A1/en not_active Abandoned
- 2014-03-07 EP EP17175815.4A patent/EP3241897B1/en active Active
- 2014-03-07 US US14/773,337 patent/US20160017048A1/en not_active Abandoned
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2016
- 2016-07-11 HK HK18105499.5A patent/HK1245841B/en not_active IP Right Cessation
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2018
- 2018-09-21 JP JP2018176745A patent/JP6678215B2/ja not_active Expired - Fee Related
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2019
- 2019-12-09 AU AU2019275678A patent/AU2019275678A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009080829A1 (en) * | 2007-12-26 | 2009-07-02 | Biotest Ag | Agents targeting cd138 and uses thereof |
Non-Patent Citations (1)
| Title |
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| Laurence Cooper, "T-Cell Immunotherapies for Treating Breast Cancer", (2011-09-01), pages 1 - 16, URL: http://www.dtic.mil/dtic/tr/fulltext/u2/a554845.pdf, (2014-07-01) * |
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| AU2014225365A1 (en) | 2015-10-08 |
| EP2964753B1 (en) | 2018-04-25 |
| ES2671004T3 (es) | 2018-06-04 |
| JP2019010117A (ja) | 2019-01-24 |
| EP3241897A1 (en) | 2017-11-08 |
| JP2016510597A (ja) | 2016-04-11 |
| HK1219981A1 (en) | 2017-04-21 |
| WO2014138704A1 (en) | 2014-09-12 |
| JP6409009B2 (ja) | 2018-10-17 |
| JP6678215B2 (ja) | 2020-04-08 |
| AU2019275678A1 (en) | 2020-01-02 |
| US20160017048A1 (en) | 2016-01-21 |
| CA2904369A1 (en) | 2014-09-12 |
| EP3456818A1 (en) | 2019-03-20 |
| EP3241897B1 (en) | 2018-10-03 |
| EP2964753A1 (en) | 2016-01-13 |
| HK1245841B (en) | 2019-11-15 |
| CN105339498A (zh) | 2016-02-17 |
| EP3456818B1 (en) | 2020-05-20 |
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