AU2013360026B2 - Methods of treating or preventing respiratory conditions - Google Patents

Methods of treating or preventing respiratory conditions Download PDF

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Publication number
AU2013360026B2
AU2013360026B2 AU2013360026A AU2013360026A AU2013360026B2 AU 2013360026 B2 AU2013360026 B2 AU 2013360026B2 AU 2013360026 A AU2013360026 A AU 2013360026A AU 2013360026 A AU2013360026 A AU 2013360026A AU 2013360026 B2 AU2013360026 B2 AU 2013360026B2
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AU
Australia
Prior art keywords
cells
stro
population
asthma
progeny
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2013360026A
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English (en)
Other versions
AU2013360026A1 (en
Inventor
Peter Ghosh
Silviu Itescu
Ravi Krishnan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mesoblast Inc
Original Assignee
Mesoblast Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mesoblast Inc filed Critical Mesoblast Inc
Publication of AU2013360026A1 publication Critical patent/AU2013360026A1/en
Application granted granted Critical
Publication of AU2013360026B2 publication Critical patent/AU2013360026B2/en
Priority to AU2018226514A priority Critical patent/AU2018226514B2/en
Priority to AU2020202022A priority patent/AU2020202022A1/en
Priority to AU2022209219A priority patent/AU2022209219B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU2013360026A 2012-12-12 2013-12-12 Methods of treating or preventing respiratory conditions Active AU2013360026B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2018226514A AU2018226514B2 (en) 2012-12-12 2018-09-10 Methods of treating or preventing respiratory conditions
AU2020202022A AU2020202022A1 (en) 2012-12-12 2020-03-20 Methods of treating or preventing respiratory conditions
AU2022209219A AU2022209219B2 (en) 2012-12-12 2022-07-26 Methods of treating or preventing respiratory conditions

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261736352P 2012-12-12 2012-12-12
US61/736,352 2012-12-12
PCT/AU2013/001454 WO2014089625A1 (en) 2012-12-12 2013-12-12 Methods of treating or preventing respiratory conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018226514A Division AU2018226514B2 (en) 2012-12-12 2018-09-10 Methods of treating or preventing respiratory conditions

Publications (2)

Publication Number Publication Date
AU2013360026A1 AU2013360026A1 (en) 2015-07-02
AU2013360026B2 true AU2013360026B2 (en) 2018-06-21

Family

ID=50933587

Family Applications (4)

Application Number Title Priority Date Filing Date
AU2013360026A Active AU2013360026B2 (en) 2012-12-12 2013-12-12 Methods of treating or preventing respiratory conditions
AU2018226514A Active AU2018226514B2 (en) 2012-12-12 2018-09-10 Methods of treating or preventing respiratory conditions
AU2020202022A Abandoned AU2020202022A1 (en) 2012-12-12 2020-03-20 Methods of treating or preventing respiratory conditions
AU2022209219A Active AU2022209219B2 (en) 2012-12-12 2022-07-26 Methods of treating or preventing respiratory conditions

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2018226514A Active AU2018226514B2 (en) 2012-12-12 2018-09-10 Methods of treating or preventing respiratory conditions
AU2020202022A Abandoned AU2020202022A1 (en) 2012-12-12 2020-03-20 Methods of treating or preventing respiratory conditions
AU2022209219A Active AU2022209219B2 (en) 2012-12-12 2022-07-26 Methods of treating or preventing respiratory conditions

Country Status (11)

Country Link
US (3) US10028979B2 (enExample)
EP (1) EP2931373B1 (enExample)
JP (5) JP6313327B2 (enExample)
KR (1) KR101748712B1 (enExample)
CN (2) CN105377274A (enExample)
AU (4) AU2013360026B2 (enExample)
CA (1) CA2893951C (enExample)
ES (1) ES2759281T3 (enExample)
IL (1) IL239309A0 (enExample)
SG (2) SG11201504352TA (enExample)
WO (1) WO2014089625A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2893951C (en) 2012-12-12 2022-05-03 Mesoblast, Inc. Methods of treating or preventing respiratory conditions
US20170296589A1 (en) * 2014-09-23 2017-10-19 Case Western Reserve University Compositions and methods for treating lung remodeling diseases
KR20200053501A (ko) * 2017-09-15 2020-05-18 시나타 세라퓨틱스 엘티디 알레르기성 기도 질환 (aad)/ 천식을 치료하는 방법
EP4098267A4 (en) * 2020-01-30 2024-03-06 JCR Pharmaceuticals Co., Ltd. MEDICINAL COMPOSITION COMPRISING CELLS DERIVED FROM DENTAL PULP
JP7551341B2 (ja) * 2020-06-04 2024-09-17 株式会社三共 遊技機
JP7551340B2 (ja) * 2020-06-04 2024-09-17 株式会社三共 遊技機
CN118800458B (zh) * 2024-09-14 2024-11-15 吉林大学 一种心胸外科术后并发症预测方法及系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004084921A1 (en) * 2003-03-28 2004-10-07 Angioblast Systems Incorporated Perivascular mesenchymal precursor cell induced blood vessel formation
WO2008036374A2 (en) * 2006-09-21 2008-03-27 Medistem Laboratories, Inc. Allogeneic stem cell transplants in non-conditioned recipients
US20090053182A1 (en) * 2007-05-25 2009-02-26 Medistem Laboratories, Inc. Endometrial stem cells and methods of making and using same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2287447T3 (es) * 2002-02-19 2007-12-16 Medipost, Co., Ltd. Metodos de aislamiento y expansion del cultivo de celulas troncales/madre mesenquimatosas a partir de sangre del cordon umbilical, y metodo de diferenciacion de celulas troncales/madre mesenquimatosas derivadas de sangre del cordon umbilical en diversos tejidos mesenquimatosos.
US20080095749A1 (en) * 2004-03-22 2008-04-24 Sudeepta Aggarwal Mesenchymal stem cells and uses therefor
CN101506355B (zh) 2004-09-24 2012-06-27 成血管细胞系统公司 多能扩增间充质前体细胞子代(memp)及其应用
CN101248171B (zh) 2005-04-12 2015-11-25 迈索布拉斯特股份有限公司 通过组织非特异性碱性磷酸酶分离成人多潜能细胞
US9381216B2 (en) * 2007-08-06 2016-07-05 Mesoblast, Inc. Methods of generating, repairing and/or maintaining connective tissue in vivo
DK2205721T3 (en) * 2007-10-17 2016-10-24 Txcell TR1 cells mesenchymal stem cells and uses thereof
EP2324109B1 (en) * 2008-09-03 2016-10-26 Mesoblast, Inc. Expansion of haemopoietic precursors
KR101891260B1 (ko) * 2010-07-02 2018-08-24 메소블라스트, 아이엔씨. T-세포 매개된 면역 질환의 치료
US9901600B2 (en) * 2011-03-11 2018-02-27 Children's Medical Center Corporation Methods and compositions relating to mesenchymal stem cell exosomes
AU2012262675B2 (en) 2011-06-03 2016-05-19 Mesoblast, Inc Methods of treating or preventing neurological diseases
CA2893951C (en) 2012-12-12 2022-05-03 Mesoblast, Inc. Methods of treating or preventing respiratory conditions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004084921A1 (en) * 2003-03-28 2004-10-07 Angioblast Systems Incorporated Perivascular mesenchymal precursor cell induced blood vessel formation
WO2008036374A2 (en) * 2006-09-21 2008-03-27 Medistem Laboratories, Inc. Allogeneic stem cell transplants in non-conditioned recipients
US20090053182A1 (en) * 2007-05-25 2009-02-26 Medistem Laboratories, Inc. Endometrial stem cells and methods of making and using same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BONFIELD ET AL., "Human mesenchymal stem cells suppress chronic airway inflammation in the murine ovalbumin asthma model.", AM J PHYSIOL LUNG CELL MOL PHYSIOL, (2010), vol. 299, pages L760 - L770 *

Also Published As

Publication number Publication date
US20200289578A1 (en) 2020-09-17
IL239309A0 (en) 2015-07-30
WO2014089625A1 (en) 2014-06-19
AU2018226514A1 (en) 2018-09-27
CA2893951A1 (en) 2014-06-19
US10688134B2 (en) 2020-06-23
HK1210077A1 (en) 2016-04-15
US10028979B2 (en) 2018-07-24
JP2020097618A (ja) 2020-06-25
AU2020202022A1 (en) 2020-04-09
AU2013360026A1 (en) 2015-07-02
US20190046575A1 (en) 2019-02-14
JP2024041904A (ja) 2024-03-27
EP2931373B1 (en) 2019-08-21
US20150306146A1 (en) 2015-10-29
JP6665218B2 (ja) 2020-03-13
CN105377274A (zh) 2016-03-02
JP2016502980A (ja) 2016-02-01
EP2931373A1 (en) 2015-10-21
KR101748712B1 (ko) 2017-06-19
SG11201504352TA (en) 2015-07-30
AU2022209219A1 (en) 2022-08-18
JP2022065132A (ja) 2022-04-26
ES2759281T3 (es) 2020-05-08
JP2018118987A (ja) 2018-08-02
AU2022209219B2 (en) 2025-08-14
KR20150090237A (ko) 2015-08-05
JP7420844B2 (ja) 2024-01-23
EP2931373A4 (en) 2016-05-04
CN115919901A (zh) 2023-04-07
CA2893951C (en) 2022-05-03
JP6313327B2 (ja) 2018-04-18
SG10201807682PA (en) 2018-10-30
AU2018226514B2 (en) 2020-01-02

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