AU2013348248B2 - Methods and compositions for treating neurodegenerative diseases - Google Patents

Methods and compositions for treating neurodegenerative diseases Download PDF

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Publication number
AU2013348248B2
AU2013348248B2 AU2013348248A AU2013348248A AU2013348248B2 AU 2013348248 B2 AU2013348248 B2 AU 2013348248B2 AU 2013348248 A AU2013348248 A AU 2013348248A AU 2013348248 A AU2013348248 A AU 2013348248A AU 2013348248 B2 AU2013348248 B2 AU 2013348248B2
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AU
Australia
Prior art keywords
compound
disease
alkyl
hydrogen
alkynyl
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AU2013348248A
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AU2013348248A1 (en
Inventor
Chih-Ming Chen
Sheng-Yung Liu
Wu-Che Wen
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Golden Biotechnology Corp
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Golden Biotechnology Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Dermatology (AREA)
AU2013348248A 2012-11-21 2013-11-18 Methods and compositions for treating neurodegenerative diseases Active AU2013348248B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261729295P 2012-11-21 2012-11-21
US61/729,295 2012-11-21
PCT/US2013/070625 WO2014081675A1 (en) 2012-11-21 2013-11-18 Methods and compositions for treating neurodegenerative diseases

Publications (2)

Publication Number Publication Date
AU2013348248A1 AU2013348248A1 (en) 2015-07-02
AU2013348248B2 true AU2013348248B2 (en) 2018-06-14

Family

ID=50728525

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013348248A Active AU2013348248B2 (en) 2012-11-21 2013-11-18 Methods and compositions for treating neurodegenerative diseases

Country Status (13)

Country Link
US (1) US9861592B2 (OSRAM)
EP (1) EP2922534B1 (OSRAM)
JP (1) JP6407876B2 (OSRAM)
KR (1) KR102088078B1 (OSRAM)
CN (1) CN104968339B (OSRAM)
AU (1) AU2013348248B2 (OSRAM)
BR (1) BR112015011798A2 (OSRAM)
CA (1) CA2892084C (OSRAM)
ES (1) ES2788598T3 (OSRAM)
MX (1) MX2015006337A (OSRAM)
TW (1) TWI559917B (OSRAM)
WO (1) WO2014081675A1 (OSRAM)
ZA (1) ZA201504292B (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016037566A1 (en) * 2014-09-09 2016-03-17 Ching-Feng Weng Use of antroqiononol for treating obesity, and process for preparation of antroquinonol
CN107847473B (zh) * 2015-05-29 2021-08-10 香港大学 新型神经保护性和神经修复性n-炔丙基咖啡酰胺(paca)及作为神经变性疾病的疗法的用途
TW201733573A (zh) * 2016-03-25 2017-10-01 郭盈妤 牛樟芝化合物用於製備治療及預防神經退行性疾病之藥物的用途
CN107296805A (zh) * 2016-04-14 2017-10-27 郭盈妤 牛樟芝化合物及其萃取物用于制备治疗及预防神经退行性疾病的药物的用途
US11406605B2 (en) * 2017-12-20 2022-08-09 Golden Biotechnology Corporation Therapeutic compositions for treating pancreatic cancer
WO2019160150A1 (ja) * 2018-02-19 2019-08-22 國子 草間 バレロラクトン(Valerolactone)系新規化合物、及び、医薬
TW202038981A (zh) * 2018-11-28 2020-11-01 薩摩亞商吉亞生技控股股份有限公司 治療失智症的組合物及方法
US11111263B2 (en) * 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
CN110200998B (zh) * 2019-05-24 2021-04-16 清华大学 神经元来源外泌体的制备及其在治疗老年痴呆症中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120071426A1 (en) * 2010-09-20 2012-03-22 Golden Biotechnology Corporation Methods and compositions for treating lung cancer
WO2013148701A1 (en) * 2012-03-26 2013-10-03 Golden Biotechnology Corporation Methods and compositions for treating arteriosclerotic vascular diseases

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3993073A (en) 1969-04-01 1976-11-23 Alza Corporation Novel drug delivery device
US3598122A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3710795A (en) 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
US4069307A (en) 1970-10-01 1978-01-17 Alza Corporation Drug-delivery device comprising certain polymeric materials for controlled release of drug
US3731683A (en) 1971-06-04 1973-05-08 Alza Corp Bandage for the controlled metering of topical drugs to the skin
US3996934A (en) 1971-08-09 1976-12-14 Alza Corporation Medical bandage
US3742951A (en) 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
US3921636A (en) 1973-01-15 1975-11-25 Alza Corp Novel drug delivery device
US3993072A (en) 1974-08-28 1976-11-23 Alza Corporation Microporous drug delivery device
US3972995A (en) 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
US4077407A (en) 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4031894A (en) 1975-12-08 1977-06-28 Alza Corporation Bandage for transdermally administering scopolamine to prevent nausea
US4031893A (en) 1976-05-14 1977-06-28 Survival Technology, Inc. Hypodermic injection device having means for varying the medicament capacity thereof
US4060084A (en) 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
US4201211A (en) 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
JPS5562012A (en) 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
US4230105A (en) 1978-11-13 1980-10-28 Merck & Co., Inc. Transdermal delivery of drugs
US4291015A (en) 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US5116817A (en) 1982-12-10 1992-05-26 Syntex (U.S.A.) Inc. LHRH preparations for intranasal administration
US4476116A (en) 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
US5312325A (en) 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
US5633009A (en) 1990-11-28 1997-05-27 Sano Corporation Transdermal administration of azapirones
WO1995031235A1 (en) 1994-05-16 1995-11-23 Washington Biotech Corporation Modular automatic or manual emergency medicine injection system
US5358489A (en) 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5540664A (en) 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5665378A (en) 1994-09-30 1997-09-09 Davis; Roosevelt Transdermal therapeutic formulation
US6929801B2 (en) 1996-02-19 2005-08-16 Acrux Dds Pty Ltd Transdermal delivery of antiparkinson agents
US6923983B2 (en) 1996-02-19 2005-08-02 Acrux Dds Pty Ltd Transdermal delivery of hormones
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
US5869090A (en) 1998-01-20 1999-02-09 Rosenbaum; Jerry Transdermal delivery of dehydroepiandrosterone
US6946144B1 (en) 1998-07-08 2005-09-20 Oryxe Transdermal delivery system
JP4469441B2 (ja) 1999-02-10 2010-05-26 明治乳業株式会社 神経変性疾患の予防又は治療薬
US7544189B2 (en) 2000-10-10 2009-06-09 Meridian Medical Technologies, Inc. Needle and hub assembly for automatic injector
CN101166706B (zh) * 2005-02-28 2011-08-24 明治乳业株式会社 氢醌长链衍生物和/或苯氧基长链衍生物及含有它们的药品
TW200829234A (en) * 2007-01-08 2008-07-16 Golden Biotechnology Corp Antrodia camphorata isophorone extract
TWI394573B (zh) * 2007-06-14 2013-05-01 國鼎生物科技股份有限公司 Application of Cynanchum auranthone Cyclohexenone Compounds in the Preparation of Drugs for Liver Protection
FR2987264A1 (fr) * 2012-02-23 2013-08-30 Golden Biotechnology Corp Methodes et compositions pour le traitement des metastases cancereuses

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120071426A1 (en) * 2010-09-20 2012-03-22 Golden Biotechnology Corporation Methods and compositions for treating lung cancer
WO2013148701A1 (en) * 2012-03-26 2013-10-03 Golden Biotechnology Corporation Methods and compositions for treating arteriosclerotic vascular diseases

Also Published As

Publication number Publication date
CA2892084A1 (en) 2014-05-30
US9861592B2 (en) 2018-01-09
AU2013348248A1 (en) 2015-07-02
ES2788598T3 (es) 2020-10-22
TW201440758A (zh) 2014-11-01
EP2922534A4 (en) 2016-05-11
EP2922534A1 (en) 2015-09-30
ZA201504292B (en) 2017-04-26
JP2016500074A (ja) 2016-01-07
CA2892084C (en) 2020-11-10
JP6407876B2 (ja) 2018-10-17
CN104968339B (zh) 2019-06-11
BR112015011798A2 (pt) 2017-07-11
WO2014081675A1 (en) 2014-05-30
CN104968339A (zh) 2015-10-07
US20140142194A1 (en) 2014-05-22
HK1215548A1 (zh) 2016-09-02
MX2015006337A (es) 2015-09-07
TWI559917B (en) 2016-12-01
KR20150087844A (ko) 2015-07-30
KR102088078B1 (ko) 2020-03-12
EP2922534B1 (en) 2020-04-08

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