AU2013311714C1 - Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases - Google Patents

Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases Download PDF

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Publication number
AU2013311714C1
AU2013311714C1 AU2013311714A AU2013311714A AU2013311714C1 AU 2013311714 C1 AU2013311714 C1 AU 2013311714C1 AU 2013311714 A AU2013311714 A AU 2013311714A AU 2013311714 A AU2013311714 A AU 2013311714A AU 2013311714 C1 AU2013311714 C1 AU 2013311714C1
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deficiency
thr
gly
glu
pro
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AU2013311714A
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AU2013311714B2 (en
AU2013311714A1 (en
Inventor
Bo Akerstrom
Magnus Gram
Lena Rosenlof
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Guard Therapeutics International AB
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A1M Pharma AB
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1722—Plasma globulins, lactoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2013311714A 2012-09-05 2013-09-04 Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases Ceased AU2013311714C1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201270538 2012-09-05
DKPA201270538 2012-09-05
DKPA201270557 2012-09-12
DKPA201270557 2012-09-12
PCT/EP2013/068270 WO2014037390A1 (en) 2012-09-05 2013-09-04 Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases

Publications (3)

Publication Number Publication Date
AU2013311714A1 AU2013311714A1 (en) 2015-03-12
AU2013311714B2 AU2013311714B2 (en) 2017-10-12
AU2013311714C1 true AU2013311714C1 (en) 2018-01-25

Family

ID=49162118

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013311714A Ceased AU2013311714C1 (en) 2012-09-05 2013-09-04 Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases

Country Status (21)

Country Link
US (1) US10226507B2 (enExample)
EP (1) EP2900254B1 (enExample)
JP (2) JP2015533790A (enExample)
KR (1) KR20150047510A (enExample)
CN (1) CN104661673A (enExample)
AU (1) AU2013311714C1 (enExample)
BR (1) BR112015003957A2 (enExample)
CA (1) CA2881321A1 (enExample)
DK (1) DK2900254T3 (enExample)
EA (1) EA028963B1 (enExample)
ES (1) ES2599034T3 (enExample)
HR (1) HRP20161364T1 (enExample)
HU (1) HUE030559T2 (enExample)
IN (1) IN2015DN00515A (enExample)
MX (1) MX357656B (enExample)
NZ (1) NZ629621A (enExample)
PL (1) PL2900254T3 (enExample)
PT (1) PT2900254T (enExample)
SG (1) SG11201500669SA (enExample)
WO (1) WO2014037390A1 (enExample)
ZA (1) ZA201500547B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016204360A (ja) * 2015-02-25 2016-12-08 エー１エム ファーマ エービーＡ１Ｍ Ｐｈａｒｍａ ＡＢ 放射性核種療法における腎臓の保護に用いるためのアルファ−１−ミクログロブリン
KR20180116385A (ko) * 2016-02-25 2018-10-24 에이원엠 파마 에이비 조영제의 사용과 관련하여 신장 보호에서 이용하기 위한 알파-1-마이크로글로불린
ES2896734T3 (es) 2016-03-18 2022-02-25 Guard Therapeutics Int Ab Proteínas novedosas derivadas de la alfa-1-microglobulina y su uso
GB2566516A (en) 2017-09-15 2019-03-20 Univ Oxford Innovation Ltd Electrochemical recognition and quantification of cytochrome c oxidase expression in bacteria
CN109867717A (zh) * 2019-04-01 2019-06-11 山西瑞亚力生物技术有限公司 一种血浆中α1微球蛋白的提取方法
CN110452980B (zh) * 2019-09-23 2023-07-28 武汉儿童医院 一种线粒体脑肌病诊断试剂盒及应用
US20220362293A1 (en) * 2019-09-25 2022-11-17 Cytegen Corp. Treatment of Mitochondrial Deficits and Age-Related Diseases Using Blood Products
CN115575646B (zh) * 2022-11-21 2023-04-28 四川大学华西医院 一种代谢标志物组在制备预测癫痫发作的试剂盒中的用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010006809A2 (en) * 2008-07-18 2010-01-21 Akerstroem Bo Medical use of the radical scavenger and antioxidant alpha-1-microglobulin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2547124A1 (en) * 2003-11-26 2005-06-09 Sanofi-Aventis Deutschland Gmbh Tubular proteinuria as an indicator for elevated cardiovascular risk
MX347788B (es) * 2007-02-12 2017-05-12 A1M Pharma Ab Diagnosis y tratamiento de preeclampsia.
EP2300614B1 (en) * 2008-02-04 2015-10-28 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Methods and compositions for treatment of mitochondrial disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010006809A2 (en) * 2008-07-18 2010-01-21 Akerstroem Bo Medical use of the radical scavenger and antioxidant alpha-1-microglobulin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MAY, K et al. "Perfusion of human placenta with hemoglobin introduces preeclampsia-like injuries that are prevented by a1-microglobulin". PLACENTA, 2011, Vol. 32, pages: 323-332 *

Also Published As

Publication number Publication date
US10226507B2 (en) 2019-03-12
CN104661673A (zh) 2015-05-27
PL2900254T3 (pl) 2017-02-28
HRP20161364T1 (hr) 2016-12-16
AU2013311714B2 (en) 2017-10-12
ZA201500547B (en) 2017-09-27
MX357656B (es) 2018-07-18
IN2015DN00515A (enExample) 2015-06-26
SG11201500669SA (en) 2015-02-27
MX2015002604A (es) 2015-06-10
AU2013311714A1 (en) 2015-03-12
EP2900254A1 (en) 2015-08-05
JP2018203756A (ja) 2018-12-27
EA201590503A1 (ru) 2015-06-30
KR20150047510A (ko) 2015-05-04
BR112015003957A2 (pt) 2017-08-08
NZ629621A (en) 2015-09-25
JP2015533790A (ja) 2015-11-26
EP2900254B1 (en) 2016-08-03
DK2900254T3 (en) 2016-08-29
HK1210585A1 (en) 2016-04-29
EA028963B1 (ru) 2018-01-31
ES2599034T3 (es) 2017-01-31
WO2014037390A1 (en) 2014-03-13
CA2881321A1 (en) 2014-03-13
US20150258171A1 (en) 2015-09-17
PT2900254T (pt) 2016-10-18
HUE030559T2 (en) 2017-05-29

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