AU2013255050B2 - Methods for treating and diagnosing blinding eye diseases - Google Patents

Methods for treating and diagnosing blinding eye diseases Download PDF

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Publication number
AU2013255050B2
AU2013255050B2 AU2013255050A AU2013255050A AU2013255050B2 AU 2013255050 B2 AU2013255050 B2 AU 2013255050B2 AU 2013255050 A AU2013255050 A AU 2013255050A AU 2013255050 A AU2013255050 A AU 2013255050A AU 2013255050 B2 AU2013255050 B2 AU 2013255050B2
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subject
compound
faf
eye
agent
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AU2013255050A1 (en
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Shelley Romayne BOYD
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Translatum Medicus Inc
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TRANSLATUM MEDICUS Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/16—Ophthalmology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2013255050A 2012-05-01 2013-04-30 Methods for treating and diagnosing blinding eye diseases Active AU2013255050B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2016219703A AU2016219703B2 (en) 2012-05-01 2016-08-26 Methods for treating and diagnosing blinding eye diseases

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261640854P 2012-05-01 2012-05-01
US61/640,854 2012-05-01
US201261641393P 2012-05-02 2012-05-02
US61/641,393 2012-05-02
US201261693226P 2012-08-24 2012-08-24
US61/693,226 2012-08-24
US201361792436P 2013-03-15 2013-03-15
US61/792,436 2013-03-15
PCT/CA2013/050335 WO2013163758A1 (en) 2012-05-01 2013-04-30 Methods for treating and diagnosing blinding eye diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016219703A Division AU2016219703B2 (en) 2012-05-01 2016-08-26 Methods for treating and diagnosing blinding eye diseases

Publications (2)

Publication Number Publication Date
AU2013255050A1 AU2013255050A1 (en) 2014-11-13
AU2013255050B2 true AU2013255050B2 (en) 2016-07-28

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AU2013255050A Active AU2013255050B2 (en) 2012-05-01 2013-04-30 Methods for treating and diagnosing blinding eye diseases
AU2016219703A Active AU2016219703B2 (en) 2012-05-01 2016-08-26 Methods for treating and diagnosing blinding eye diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2016219703A Active AU2016219703B2 (en) 2012-05-01 2016-08-26 Methods for treating and diagnosing blinding eye diseases

Country Status (9)

Country Link
EP (2) EP2844250B1 (https=)
JP (3) JP2015523546A (https=)
CN (2) CN104334173B (https=)
AU (2) AU2013255050B2 (https=)
CA (2) CA3095012C (https=)
DK (1) DK2844250T3 (https=)
ES (1) ES2656292T3 (https=)
IL (3) IL235395A (https=)
WO (1) WO2013163758A1 (https=)

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US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
ES2789849T3 (es) * 2014-05-15 2020-10-26 Translatum Medicus Inc Composiciones y procedimientos para el tratamiento y diagnóstico de trastornos oculares
CA2989270A1 (en) * 2015-06-16 2016-12-22 Translatum Medicus, Inc. Compositions and methods for treating and diagnosing ocular disorders
JP6664115B2 (ja) * 2016-03-15 2020-03-13 原　英彰 アフリベルセプトによる網膜保護作用
CN109788946B (zh) * 2016-06-24 2023-02-03 鲁美斯Be有限公司 利用激光等效强脉冲光装置的选择性皮肤处理
EP3525659A4 (en) 2016-10-13 2020-06-17 Translatum Medicus, Inc. SYSTEMS AND METHODS FOR DETECTING EYE DISEASES
CN110213987A (zh) * 2016-12-05 2019-09-06 杰克逊实验室 视网膜和视神经中的脂肪滴作为人类的神经变性和青光眼的诊断标志物
US20210060017A1 (en) * 2018-02-27 2021-03-04 Shilpa Medicare Ltd Methotrexate ophthalmic solution
CN111970957B (zh) * 2018-04-18 2024-02-27 株式会社尼康 图像处理方法、计算机可读的存储介质及图像处理装置
CN118505665A (zh) * 2018-04-18 2024-08-16 株式会社尼康 图像处理方法、图像处理装置、存储介质及眼科系统
CN109222890A (zh) * 2018-08-24 2019-01-18 微云（武汉）科技有限公司 一种眼睛健康情况确定方法、装置和存储介质
CN109585017B (zh) * 2019-01-31 2023-12-12 上海宝藤生物医药科技股份有限公司 一种年龄相关性黄斑变性的风险预测算法模型和装置
WO2020261158A1 (en) 2019-06-25 2020-12-30 Translatum Medicus Inc. Processes of making 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives
AU2021225926A1 (en) 2020-02-26 2022-10-20 Case Western Reserve University Compositions and methods for treating misfolded protein ocular disorders
JP7406403B2 (ja) 2020-02-28 2023-12-27 浜松ホトニクス株式会社 眼底画像処理方法、眼底画像処理装置、眼底画像処理プログラム、及びそのプログラムを記録する記録媒体
CN114099515A (zh) * 2021-12-27 2022-03-01 中山大学中山眼科中心 氨甲蝶呤在制备治疗视网膜色素变性的药物方面的应用
WO2024165925A1 (en) * 2023-02-10 2024-08-15 Translatum Medicus Inc. Bindarit conjugates, compositions and methods for treating ocular diseases or disorders

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Also Published As

Publication number Publication date
IL254995B (en) 2018-08-30
CN104334173B (zh) 2017-05-03
IL254995A0 (en) 2017-12-31
JP2019194230A (ja) 2019-11-07
JP6837522B2 (ja) 2021-03-03
CN107050020A (zh) 2017-08-18
JP2015523546A (ja) 2015-08-13
WO2013163758A1 (en) 2013-11-07
ES2656292T3 (es) 2018-02-26
CA2911041A1 (en) 2013-11-07
AU2016219703B2 (en) 2017-09-14
DK2844250T3 (en) 2018-01-08
EP2844250B1 (en) 2017-11-08
AU2013255050A1 (en) 2014-11-13
CA2911041C (en) 2020-12-15
JP2017114894A (ja) 2017-06-29
CN104334173A (zh) 2015-02-04
CA3095012C (en) 2023-02-07
AU2016219703A1 (en) 2016-09-15
IL235395A (en) 2017-10-31
EP2844250A4 (en) 2015-11-18
EP3338776A1 (en) 2018-06-27
EP2844250A1 (en) 2015-03-11
IL260714B (en) 2019-08-29
CA3095012A1 (en) 2013-11-07

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