AU2013244969B2 - Method for the enzymatic production of isoprenol using mevalonate as a substrate - Google Patents

Method for the enzymatic production of isoprenol using mevalonate as a substrate Download PDF

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Publication number
AU2013244969B2
AU2013244969B2 AU2013244969A AU2013244969A AU2013244969B2 AU 2013244969 B2 AU2013244969 B2 AU 2013244969B2 AU 2013244969 A AU2013244969 A AU 2013244969A AU 2013244969 A AU2013244969 A AU 2013244969A AU 2013244969 B2 AU2013244969 B2 AU 2013244969B2
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AU
Australia
Prior art keywords
amino acid
acid sequence
seq
protein
mevalonate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2013244969A
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English (en)
Other versions
AU2013244969A1 (en
Inventor
Maria Anissimova
Marc Delcourt
Philippe Marliere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Bioenergies SA
Scientist of Fortune SA
Original Assignee
Global Bioenergies SA
Scientist of Fortune SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Global Bioenergies SA, Scientist of Fortune SA filed Critical Global Bioenergies SA
Publication of AU2013244969A1 publication Critical patent/AU2013244969A1/en
Application granted granted Critical
Publication of AU2013244969B2 publication Critical patent/AU2013244969B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01033—Diphosphomevalonate decarboxylase (4.1.1.33), i.e. mevalonate-pyrophosphate decarboxylase

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
AU2013244969A 2012-04-05 2013-04-04 Method for the enzymatic production of isoprenol using mevalonate as a substrate Ceased AU2013244969B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12163330.9 2012-04-05
EP12163330 2012-04-05
PCT/EP2013/057108 WO2013150100A1 (en) 2012-04-05 2013-04-04 Method for the enzymatic production of isoprenol using mevalonate as a substrate

Publications (2)

Publication Number Publication Date
AU2013244969A1 AU2013244969A1 (en) 2014-10-02
AU2013244969B2 true AU2013244969B2 (en) 2017-03-02

Family

ID=48236862

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013244969A Ceased AU2013244969B2 (en) 2012-04-05 2013-04-04 Method for the enzymatic production of isoprenol using mevalonate as a substrate

Country Status (9)

Country Link
US (1) US9879286B2 (enExample)
EP (1) EP2834365A1 (enExample)
CN (1) CN104245945B (enExample)
AU (1) AU2013244969B2 (enExample)
BR (1) BR112014024493A2 (enExample)
CA (1) CA2867980A1 (enExample)
IN (1) IN2014DN08134A (enExample)
SG (1) SG2014013098A (enExample)
WO (1) WO2013150100A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013032516A2 (pt) 2011-06-17 2017-03-01 Invista Tech Sarl método de biosintetizar butadieno e método para produzir butadieno
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
US9777295B2 (en) 2012-11-28 2017-10-03 Invista North America S.A.R.L. Methods for biosynthesis of isobutene
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
CN105683385A (zh) 2013-08-05 2016-06-15 英威达技术有限责任公司 用于生物合成异戊二烯的方法
EP3030668A1 (en) 2013-08-05 2016-06-15 Invista Technologies S.A R.L. Methods for biosynthesis of isobutene
US20170152531A1 (en) 2014-06-16 2017-06-01 North America S.A.R.L. Process for producing glutarate and glutaric acid methyl ester
ES2749911T3 (es) 2015-06-26 2020-03-24 Global Bioenergies Procedimiento de producción enzimática de alcohol isoamílico
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
KR20230035365A (ko) * 2020-07-08 2023-03-13 더 리전츠 오브 더 유니버시티 오브 캘리포니아 이소프레놀의 생산에 유용한 변형된 효모 숙주 세포
CN115992126A (zh) * 2021-10-18 2023-04-21 中国石油化工股份有限公司 酶的组合、表达载体、工程菌株以及它们的应用和生产异戊烯醇和/或异戊二烯的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011076261A1 (en) * 2009-12-22 2011-06-30 Global Bioenergies Process for the production of isoprenol from mevalonate employing a diphosphomevalonate decarboxylase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007139925A2 (en) * 2006-05-26 2007-12-06 Amyris Biotechnologies, Inc. Fuel components, fuel compositions and methods of making and using same
EP3354740A1 (en) 2007-12-13 2018-08-01 Danisco US Inc. Compositions and methods for producing isoprene

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011076261A1 (en) * 2009-12-22 2011-06-30 Global Bioenergies Process for the production of isoprenol from mevalonate employing a diphosphomevalonate decarboxylase

Also Published As

Publication number Publication date
CN104245945A (zh) 2014-12-24
WO2013150100A1 (en) 2013-10-10
US20150118725A1 (en) 2015-04-30
EP2834365A1 (en) 2015-02-11
CN104245945B (zh) 2018-10-09
SG2014013098A (en) 2014-10-30
IN2014DN08134A (enExample) 2015-05-01
AU2013244969A1 (en) 2014-10-02
BR112014024493A2 (pt) 2017-08-08
US9879286B2 (en) 2018-01-30
CA2867980A1 (en) 2013-10-10

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