AU2012358244A1 - Methods and materials for assessing loss of heterozygosity - Google Patents

Methods and materials for assessing loss of heterozygosity Download PDF

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Publication number
AU2012358244A1
AU2012358244A1 AU2012358244A AU2012358244A AU2012358244A1 AU 2012358244 A1 AU2012358244 A1 AU 2012358244A1 AU 2012358244 A AU2012358244 A AU 2012358244A AU 2012358244 A AU2012358244 A AU 2012358244A AU 2012358244 A1 AU2012358244 A1 AU 2012358244A1
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Australia
Prior art keywords
cancer
loh
length
patient
pair
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Abandoned
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AU2012358244A
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Victor Abkevich
Alexander Gutin
Jerry Lanchbury
Kirsten Timms
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Myriad Genetics Inc
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Myriad Genetics Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48669561&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2012358244(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Myriad Genetics Inc filed Critical Myriad Genetics Inc
Publication of AU2012358244A1 publication Critical patent/AU2012358244A1/en
Assigned to MYRIAD GENETICS, INC. reassignment MYRIAD GENETICS, INC. Request for Assignment Assignors: ABKEVICH, VICTOR, GUTIN, ALEXANDER, LATCHBURY, JERRY, MYRIAD GENETICS, INC., TIMMS, KIRSTEN
Priority to AU2018211277A priority Critical patent/AU2018211277B2/en
Priority to AU2020223754A priority patent/AU2020223754B2/en
Priority to AU2022228167A priority patent/AU2022228167B2/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10Ploidy or copy number detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Inorganic Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2012358244A 2011-12-21 2012-12-21 Methods and materials for assessing loss of heterozygosity Abandoned AU2012358244A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2018211277A AU2018211277B2 (en) 2011-12-21 2018-08-02 Methods and materials for assessing loss of heterozygosity
AU2020223754A AU2020223754B2 (en) 2011-12-21 2020-08-28 Methods and materials for assessing loss of heterozygosity
AU2022228167A AU2022228167B2 (en) 2011-12-21 2022-09-08 Methods and materials for assessing loss of heterozygosity

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161578713P 2011-12-21 2011-12-21
US61/578,713 2011-12-21
US201261654402P 2012-06-01 2012-06-01
US61/654,402 2012-06-01
PCT/US2012/071380 WO2013096843A1 (en) 2011-12-21 2012-12-21 Methods and materials for assessing loss of heterozygosity

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018211277A Division AU2018211277B2 (en) 2011-12-21 2018-08-02 Methods and materials for assessing loss of heterozygosity

Publications (1)

Publication Number Publication Date
AU2012358244A1 true AU2012358244A1 (en) 2014-06-12

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Family Applications (4)

Application Number Title Priority Date Filing Date
AU2012358244A Abandoned AU2012358244A1 (en) 2011-12-21 2012-12-21 Methods and materials for assessing loss of heterozygosity
AU2018211277A Active AU2018211277B2 (en) 2011-12-21 2018-08-02 Methods and materials for assessing loss of heterozygosity
AU2020223754A Active AU2020223754B2 (en) 2011-12-21 2020-08-28 Methods and materials for assessing loss of heterozygosity
AU2022228167A Active AU2022228167B2 (en) 2011-12-21 2022-09-08 Methods and materials for assessing loss of heterozygosity

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2018211277A Active AU2018211277B2 (en) 2011-12-21 2018-08-02 Methods and materials for assessing loss of heterozygosity
AU2020223754A Active AU2020223754B2 (en) 2011-12-21 2020-08-28 Methods and materials for assessing loss of heterozygosity
AU2022228167A Active AU2022228167B2 (en) 2011-12-21 2022-09-08 Methods and materials for assessing loss of heterozygosity

Country Status (11)

Country Link
US (5) US9388472B2 (enExample)
EP (3) EP2794907B2 (enExample)
JP (5) JP6325453B2 (enExample)
CN (2) CN104160037B (enExample)
AU (4) AU2012358244A1 (enExample)
BR (1) BR112014015152A2 (enExample)
CA (1) CA2860312C (enExample)
DK (1) DK2794907T4 (enExample)
ES (1) ES2759533T5 (enExample)
FI (1) FI2794907T4 (enExample)
WO (1) WO2013096843A1 (enExample)

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