AU2012323392A1 - Integrated microneedle array delivery system - Google Patents
Integrated microneedle array delivery system Download PDFInfo
- Publication number
- AU2012323392A1 AU2012323392A1 AU2012323392A AU2012323392A AU2012323392A1 AU 2012323392 A1 AU2012323392 A1 AU 2012323392A1 AU 2012323392 A AU2012323392 A AU 2012323392A AU 2012323392 A AU2012323392 A AU 2012323392A AU 2012323392 A1 AU2012323392 A1 AU 2012323392A1
- Authority
- AU
- Australia
- Prior art keywords
- housing
- array
- skin
- carrier assembly
- stored energy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 claims abstract description 25
- 239000012528 membrane Substances 0.000 claims description 40
- 230000004913 activation Effects 0.000 claims description 38
- 239000000463 material Substances 0.000 claims description 13
- 238000012546 transfer Methods 0.000 claims description 13
- 239000007787 solid Substances 0.000 claims description 6
- 210000003491 skin Anatomy 0.000 description 86
- 238000003491 array Methods 0.000 description 23
- 241001465754 Metazoa Species 0.000 description 21
- 229960000814 tetanus toxoid Drugs 0.000 description 15
- 238000005381 potential energy Methods 0.000 description 14
- 230000035515 penetration Effects 0.000 description 13
- 210000000434 stratum corneum Anatomy 0.000 description 13
- 239000003814 drug Substances 0.000 description 11
- -1 polypropylene Polymers 0.000 description 10
- 239000000853 adhesive Substances 0.000 description 9
- 230000001070 adhesive effect Effects 0.000 description 9
- 230000037317 transdermal delivery Effects 0.000 description 9
- 238000000576 coating method Methods 0.000 description 7
- 238000006073 displacement reaction Methods 0.000 description 7
- 229940079593 drug Drugs 0.000 description 7
- 239000004417 polycarbonate Substances 0.000 description 7
- 229920000515 polycarbonate Polymers 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 239000011248 coating agent Substances 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 230000001965 increasing effect Effects 0.000 description 6
- 229920000106 Liquid crystal polymer Polymers 0.000 description 5
- 239000004977 Liquid-crystal polymers (LCPs) Substances 0.000 description 5
- 241000282898 Sus scrofa Species 0.000 description 5
- 238000002965 ELISA Methods 0.000 description 4
- 239000004793 Polystyrene Substances 0.000 description 4
- 239000012790 adhesive layer Substances 0.000 description 4
- 230000002096 anti-tetanic effect Effects 0.000 description 4
- 230000003750 conditioning effect Effects 0.000 description 4
- 238000002493 microarray Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920002223 polystyrene Polymers 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 229940124597 therapeutic agent Drugs 0.000 description 4
- 230000004888 barrier function Effects 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 150000002739 metals Chemical class 0.000 description 3
- 230000000149 penetrating effect Effects 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 230000000284 resting effect Effects 0.000 description 3
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 3
- 229940043267 rhodamine b Drugs 0.000 description 3
- 238000005070 sampling Methods 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 229920004142 LEXAN™ Polymers 0.000 description 2
- 239000004418 Lexan Substances 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 2
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 2
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 150000002605 large molecules Chemical class 0.000 description 2
- 239000010410 layer Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000002831 pharmacologic agent Substances 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 229920001707 polybutylene terephthalate Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920006264 polyurethane film Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 229940122361 Bisphosphonate Drugs 0.000 description 1
- 208000019300 CLIPPERS Diseases 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- 108010041986 DNA Vaccines Proteins 0.000 description 1
- 229940021995 DNA vaccine Drugs 0.000 description 1
- 238000012286 ELISA Assay Methods 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- PIWKPBJCKXDKJR-UHFFFAOYSA-N Isoflurane Chemical compound FC(F)OC(Cl)C(F)(F)F PIWKPBJCKXDKJR-UHFFFAOYSA-N 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- DCSBSVSZJRSITC-UHFFFAOYSA-M alendronate sodium trihydrate Chemical compound O.O.O.[Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O DCSBSVSZJRSITC-UHFFFAOYSA-M 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229940103272 aluminum potassium sulfate Drugs 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 150000004663 bisphosphonates Chemical class 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- HJJVPARKXDDIQD-UHFFFAOYSA-N bromuconazole Chemical compound ClC1=CC(Cl)=CC=C1C1(CN2N=CN=C2)OCC(Br)C1 HJJVPARKXDDIQD-UHFFFAOYSA-N 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 229960004755 ceftriaxone Drugs 0.000 description 1
- VAAUVRVFOQPIGI-SPQHTLEESA-N ceftriaxone Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC1=NC(=O)C(=O)NN1C VAAUVRVFOQPIGI-SPQHTLEESA-N 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000021930 chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids Diseases 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229960002725 isoflurane Drugs 0.000 description 1
- 239000003562 lightweight material Substances 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000000944 nerve tissue Anatomy 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- GRLPQNLYRHEGIJ-UHFFFAOYSA-J potassium aluminium sulfate Chemical compound [Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRLPQNLYRHEGIJ-UHFFFAOYSA-J 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- XTUSEBKMEQERQV-UHFFFAOYSA-N propan-2-ol;hydrate Chemical compound O.CC(C)O XTUSEBKMEQERQV-UHFFFAOYSA-N 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 150000003839 salts Chemical group 0.000 description 1
- 239000008257 shaving cream Substances 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 229960005367 tetanus antitoxin Drugs 0.000 description 1
- 229920002725 thermoplastic elastomer Polymers 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000012646 vaccine adjuvant Substances 0.000 description 1
- 229940124931 vaccine adjuvant Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015227515A AU2015227515B2 (en) | 2011-10-12 | 2015-09-18 | Integrated microneedle array delivery system |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161546340P | 2011-10-12 | 2011-10-12 | |
| US61/546,340 | 2011-10-12 | ||
| PCT/US2012/059273 WO2013055638A1 (en) | 2011-10-12 | 2012-10-09 | Integrated microneedle array delivery system |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2015227515A Division AU2015227515B2 (en) | 2011-10-12 | 2015-09-18 | Integrated microneedle array delivery system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2012323392A1 true AU2012323392A1 (en) | 2014-04-24 |
Family
ID=48082330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012323392A Abandoned AU2012323392A1 (en) | 2011-10-12 | 2012-10-09 | Integrated microneedle array delivery system |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10010707B2 (instruction) |
| EP (1) | EP2766066B8 (instruction) |
| JP (1) | JP6126105B2 (instruction) |
| KR (1) | KR102022574B1 (instruction) |
| CN (1) | CN103874518A (instruction) |
| AU (1) | AU2012323392A1 (instruction) |
| CA (1) | CA2851606C (instruction) |
| IN (1) | IN2014CN02643A (instruction) |
| WO (1) | WO2013055638A1 (instruction) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103764197B (zh) | 2011-09-07 | 2017-03-15 | 3M创新有限公司 | 用于中空微针阵列的递送系统 |
| WO2014059104A1 (en) | 2012-10-10 | 2014-04-17 | 3M Innovative Properties Company | Applicator and method for applying a microneedle device to skin |
| EP2906284B8 (en) | 2012-10-10 | 2021-01-20 | Kindeva Drug Delivery L.P. | Force-controlled applicator for applying a microneedle device to skin |
| WO2014078545A1 (en) | 2012-11-16 | 2014-05-22 | 3M Innovative Properties Company | Force-controlled applicator for applying a microneedle device to skin |
| US11344708B2 (en) * | 2015-04-07 | 2022-05-31 | Lts Lohmann Therapie-Systeme Ag | Microneedle system for administering liquid formulations |
| AU2017258749B2 (en) * | 2016-04-29 | 2022-06-16 | Vivasor, Inc. | Microneedle array assembly, drug delivery device and method for administering liquid across a broad area at low pressure |
| EP3554620A4 (en) | 2016-12-16 | 2020-07-15 | Sorrento Therapeutics, Inc. | APPLICATION DEVICE FOR LIQUID DISPENSER AND METHOD FOR USE |
| DE102017117784A1 (de) * | 2017-08-04 | 2019-02-07 | Lts Lohmann Therapie-Systeme Ag | Applikatorsystem enthaltend ein Mikronadelarray aufweisend einen Wirkstoff für die Wundheilung |
| KR20200100711A (ko) * | 2017-12-19 | 2020-08-26 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 마이크로 어레이 어플리케이터 |
| WO2019166572A1 (en) | 2018-02-28 | 2019-09-06 | Pharming Intellectual Property B.V. | Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor |
| DE102019200557A1 (de) * | 2019-01-17 | 2020-07-23 | Lts Lohmann Therapie-Systeme Ag | Applikator |
| DE102019200561A1 (de) * | 2019-01-17 | 2020-07-23 | Lts Lohmann Therapie-Systeme Ag | Träger |
| KR102368260B1 (ko) * | 2020-01-09 | 2022-03-02 | 연세대학교 산학협력단 | 마이크로니들 어플리케이터 |
| WO2021221973A1 (en) | 2020-04-28 | 2021-11-04 | Ticona Llc | Microneedle assembly |
| CN115734793A (zh) * | 2020-04-28 | 2023-03-03 | 提克纳有限责任公司 | 微针组件 |
| US11389376B2 (en) | 2020-12-21 | 2022-07-19 | Mediccene Inc. | Wearable intravenous fluid delivery system |
| US11877848B2 (en) | 2021-11-08 | 2024-01-23 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US12048543B2 (en) | 2021-11-08 | 2024-07-30 | Satio, Inc. | Dermal patch for collecting a physiological sample with removable vial |
| US12053284B2 (en) | 2021-11-08 | 2024-08-06 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US12029562B2 (en) | 2021-04-14 | 2024-07-09 | Satio, Inc. | Dermal patch system |
| US11964121B2 (en) | 2021-10-13 | 2024-04-23 | Satio, Inc. | Mono dose dermal patch for pharmaceutical delivery |
| US12023156B2 (en) | 2021-10-13 | 2024-07-02 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US12214346B2 (en) | 2021-10-13 | 2025-02-04 | Satio, Inc. | Dermal patch with a diagnostic test strip |
| US12178979B2 (en) | 2021-10-13 | 2024-12-31 | Satio, Inc. | Dermal patch for delivering a pharmaceutical |
| SE545876C2 (en) | 2021-09-28 | 2024-02-27 | Biolinq Incorporated | Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device |
| USD1033641S1 (en) | 2021-12-17 | 2024-07-02 | Biolinq Incorporated | Microneedle array sensor applicator device |
| USD1057153S1 (en) | 2022-04-29 | 2025-01-07 | Biolinq Incorporated | Microneedle array sensor applicator device |
| KR20240048875A (ko) | 2022-10-07 | 2024-04-16 | 한미약품 주식회사 | 용해성 마이크로니들 어레이 및 이의 제조방법 |
| KR20240100685A (ko) | 2022-12-23 | 2024-07-02 | 한미약품 주식회사 | 마이크로니들 어레이 및 이의 제조방법 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6230051B1 (en) | 1996-06-18 | 2001-05-08 | Alza Corporation | Device for enhancing transdermal agent delivery or sampling |
| KR100453132B1 (ko) | 1996-12-20 | 2004-10-15 | 앨자 코포레이션 | 경피 약제 플럭스를 향상시키기 위한 장치 및 방법 |
| US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
| US6743211B1 (en) | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| AU2005200910B2 (en) | 1999-06-04 | 2006-08-03 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6312612B1 (en) | 1999-06-09 | 2001-11-06 | The Procter & Gamble Company | Apparatus and method for manufacturing an intracutaneous microneedle array |
| US6379324B1 (en) | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
| JP4633234B2 (ja) | 2000-07-04 | 2011-02-16 | 本田技研工業株式会社 | センサ機能の故障診断方法 |
| AU9682701A (en) | 2000-10-13 | 2002-04-22 | Alza Corp | Microblade array impact applicator |
| BR0114629A (pt) | 2000-10-13 | 2004-01-20 | Alza Corp | Aparelho e método para a perfuração da pele com microprojeções |
| US7419481B2 (en) | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
| US6821281B2 (en) * | 2000-10-16 | 2004-11-23 | The Procter & Gamble Company | Microstructures for treating and conditioning skin |
| US6591124B2 (en) * | 2001-05-11 | 2003-07-08 | The Procter & Gamble Company | Portable interstitial fluid monitoring system |
| US6881203B2 (en) | 2001-09-05 | 2005-04-19 | 3M Innovative Properties Company | Microneedle arrays and methods of manufacturing the same |
| US6830562B2 (en) | 2001-09-27 | 2004-12-14 | Unomedical A/S | Injector device for placing a subcutaneous infusion set |
| US6689100B2 (en) | 2001-10-05 | 2004-02-10 | Becton, Dickinson And Company | Microdevice and method of delivering or withdrawing a substance through the skin of an animal |
| US7004928B2 (en) | 2002-02-08 | 2006-02-28 | Rosedale Medical, Inc. | Autonomous, ambulatory analyte monitor or drug delivery device |
| US6945952B2 (en) * | 2002-06-25 | 2005-09-20 | Theraject, Inc. | Solid solution perforator for drug delivery and other applications |
| CN1691969A (zh) | 2002-07-19 | 2005-11-02 | 3M创新有限公司 | 微针装置和微针施用设备 |
| CN100479875C (zh) | 2002-07-22 | 2009-04-22 | 贝克顿·迪金森公司 | 贴片状注射装置 |
| ES2377647T3 (es) * | 2003-10-31 | 2012-03-29 | Alza Corporation | Aplicador auto-actuado para ordenamiento de microproyecciones |
| US20050228313A1 (en) | 2003-12-04 | 2005-10-13 | University Technologies International Inc. | Fluid sampling, analysis and delivery system |
| US7611481B2 (en) * | 2004-03-24 | 2009-11-03 | Corium International, Inc. | Transdermal delivery device |
| US20070073220A1 (en) | 2004-10-06 | 2007-03-29 | Philip Bunce | Inoculation device |
| JP2008520369A (ja) | 2004-11-18 | 2008-06-19 | スリーエム イノベイティブ プロパティズ カンパニー | 目立たないマイクロニードルアレイアプリケーター |
| US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
| WO2006055771A1 (en) | 2004-11-18 | 2006-05-26 | 3M Innovative Properties Company | Non-skin-contacting microneedle array applicator |
| AU2005314289A1 (en) | 2004-12-10 | 2006-06-15 | 3M Innovative Properties Company | Medical device |
| EP1871459B1 (en) | 2005-04-07 | 2019-06-19 | 3M Innovative Properties Company | System for tool feedback sensing |
| GB0509863D0 (en) * | 2005-05-16 | 2005-06-22 | Cambridge Biostability Ltd | Apparatus for administrating substances into a body |
| EP1904158B1 (en) * | 2005-06-24 | 2013-07-24 | 3M Innovative Properties Company | Collapsible patch with microneedle array |
| EP1901799B1 (en) * | 2005-06-27 | 2012-06-13 | 3M Innovative Properties Company | Microneedle array applicator device |
| EP1896115B2 (en) | 2005-06-27 | 2020-01-22 | 3M Innovative Properties Company | Microneedle cartridge assembly |
| US7232783B2 (en) | 2005-07-02 | 2007-06-19 | Lyondell Chemical Technology, L.P. | Propylene oxide catalyst and use |
| US7658728B2 (en) | 2006-01-10 | 2010-02-09 | Yuzhakov Vadim V | Microneedle array, patch, and applicator for transdermal drug delivery |
| WO2007106453A2 (en) * | 2006-03-10 | 2007-09-20 | Alza Corporation | Microprojection array application with high barrier retainer |
| US9119945B2 (en) * | 2006-04-20 | 2015-09-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
| EP2032188A1 (en) * | 2006-06-06 | 2009-03-11 | Novo Nordisk A/S | Assembly comprising skin-mountable device and packaging therefore |
| CA2676221C (en) | 2007-01-22 | 2016-12-20 | Corium International, Inc. | Applicators for microneedles |
| GB0719577D0 (en) * | 2007-10-08 | 2007-11-14 | Kirby Andrew J | Microimplant devices and methods of making and use thereof |
| US9410111B2 (en) | 2008-02-21 | 2016-08-09 | S.C. Johnson & Son, Inc. | Cleaning composition that provides residual benefits |
| EP3354312A1 (en) * | 2009-07-31 | 2018-08-01 | 3M Innovative Properties Co. | Hollow microneedle arrays |
| US20110172637A1 (en) | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Drug delivery device including tissue support structure |
| US20110172645A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Wearable drug delivery device including integrated pumping and activation elements |
-
2012
- 2012-10-09 CA CA2851606A patent/CA2851606C/en active Active
- 2012-10-09 CN CN201280050185.6A patent/CN103874518A/zh active Pending
- 2012-10-09 AU AU2012323392A patent/AU2012323392A1/en not_active Abandoned
- 2012-10-09 JP JP2014535772A patent/JP6126105B2/ja active Active
- 2012-10-09 EP EP12840675.8A patent/EP2766066B8/en active Active
- 2012-10-09 WO PCT/US2012/059273 patent/WO2013055638A1/en active Application Filing
- 2012-10-09 KR KR1020147012297A patent/KR102022574B1/ko active Active
- 2012-10-09 IN IN2643CHN2014 patent/IN2014CN02643A/en unknown
- 2012-10-09 US US14/350,156 patent/US10010707B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2851606A1 (en) | 2013-04-18 |
| JP6126105B2 (ja) | 2017-05-10 |
| KR20140077952A (ko) | 2014-06-24 |
| EP2766066A4 (en) | 2015-08-26 |
| WO2013055638A1 (en) | 2013-04-18 |
| US10010707B2 (en) | 2018-07-03 |
| IN2014CN02643A (instruction) | 2015-08-07 |
| CN103874518A (zh) | 2014-06-18 |
| EP2766066A1 (en) | 2014-08-20 |
| KR102022574B1 (ko) | 2019-09-18 |
| EP2766066B1 (en) | 2020-12-02 |
| JP2014528818A (ja) | 2014-10-30 |
| US20140257187A1 (en) | 2014-09-11 |
| EP2766066B8 (en) | 2021-01-20 |
| CA2851606C (en) | 2020-08-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2851606C (en) | Integrated microneedle array delivery system | |
| AU2012323395B2 (en) | Integrated microneedle array delivery system | |
| KR101615592B1 (ko) | 역 작동기를 포함하는 마이크로니들 주사 장치 | |
| JP5889362B2 (ja) | マイクロニードル経皮送達装置 | |
| KR101712413B1 (ko) | 카운터 조립체를 포함하는 마이크로니들 어플리케이터 | |
| EP2906284B1 (en) | Force-controlled applicator for applying a microneedle device to skin | |
| JP2019122781A (ja) | 微小突起アプリケータ | |
| CN111212675A (zh) | 用于将微针阵列施用于皮肤的施用装置 | |
| NL2007461C2 (en) | System for transporting fluid across or into a biological barrier, device and capsule as part of the system. | |
| AU2015227515B2 (en) | Integrated microneedle array delivery system | |
| RR Singh et al. | Review of patents on microneedle applicators | |
| AU2015227524B2 (en) | Integrated microneedle array delivery system | |
| WO2017179979A1 (en) | Capsule holder for accomodating a capsule for comprising fluid for transportation across or into a biological barrier, capsule, assembly of a capsule holder and a capsule and device comprising a capsule holder |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |