AU2012239977B9 - Migrastatins and uses thereof - Google Patents

Migrastatins and uses thereof Download PDF

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Publication number
AU2012239977B9
AU2012239977B9 AU2012239977A AU2012239977A AU2012239977B9 AU 2012239977 B9 AU2012239977 B9 AU 2012239977B9 AU 2012239977 A AU2012239977 A AU 2012239977A AU 2012239977 A AU2012239977 A AU 2012239977A AU 2012239977 B9 AU2012239977 B9 AU 2012239977B9
Authority
AU
Australia
Prior art keywords
aliphatic
compound
methyl
unsubstituted
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2012239977A
Other languages
English (en)
Other versions
AU2012239977A1 (en
AU2012239977B2 (en
Inventor
Manuel Valiente Cortes
Samuel J. Danishefsky
Nicolas Lecomte
Joan Massague
Malcolm Moore
Thordur OSKARSSON
Ouathek Ouerfelli
Guangli Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Memorial Sloan Kettering Cancer Center
Original Assignee
Memorial Sloan Kettering Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Memorial Sloan Kettering Cancer Center filed Critical Memorial Sloan Kettering Cancer Center
Publication of AU2012239977A1 publication Critical patent/AU2012239977A1/en
Application granted granted Critical
Publication of AU2012239977B2 publication Critical patent/AU2012239977B2/en
Publication of AU2012239977B9 publication Critical patent/AU2012239977B9/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
AU2012239977A 2011-04-07 2012-04-06 Migrastatins and uses thereof Ceased AU2012239977B9 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161473131P 2011-04-07 2011-04-07
US61/473,131 2011-04-07
US201161508275P 2011-07-15 2011-07-15
US61/508,275 2011-07-15
PCT/US2012/032642 WO2012139074A2 (en) 2011-04-07 2012-04-06 Migrastatins and uses thereof

Publications (3)

Publication Number Publication Date
AU2012239977A1 AU2012239977A1 (en) 2013-10-31
AU2012239977B2 AU2012239977B2 (en) 2016-10-20
AU2012239977B9 true AU2012239977B9 (en) 2016-11-17

Family

ID=46969857

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012239977A Ceased AU2012239977B9 (en) 2011-04-07 2012-04-06 Migrastatins and uses thereof

Country Status (7)

Country Link
US (2) US9303009B2 (enExample)
EP (1) EP2693879B1 (enExample)
JP (2) JP5975581B2 (enExample)
CN (1) CN103635088B (enExample)
AU (1) AU2012239977B9 (enExample)
CA (1) CA2832439C (enExample)
WO (1) WO2012139074A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012239977B9 (en) 2011-04-07 2016-11-17 Sloan-Kettering Institute For Cancer Research Migrastatins and uses thereof
US10285646B1 (en) * 2018-02-27 2019-05-14 CeriBell, Inc. Connection quality assessment for EEG electrode arrays
AU2019329835B2 (en) 2018-08-27 2025-05-29 Spinogenix, Inc. Fascin binding compounds for spinogenesis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070037783A1 (en) 2003-03-28 2007-02-15 Xin-Yun Huang Migrastatin analogs and uses thereof
JP4928937B2 (ja) 2003-03-28 2012-05-09 スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ ミグラスタチンアナログおよびその使用
WO2005019181A1 (en) 2003-08-19 2005-03-03 Cornell Research Foundation, Inc. Migrastatin analog cell migration inhibitors
JP5149001B2 (ja) * 2004-05-25 2013-02-20 スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ 癌の処置におけるマイグラスタチンアナログ
CA2582766C (en) * 2004-09-23 2014-07-22 Sloan-Kettering Institute For Cancer Research Isomigrastatin analogs in the treatment of cancer
WO2009070244A2 (en) 2007-11-21 2009-06-04 Cornell University Methods for inhibiting fascin
AU2012239977B9 (en) 2011-04-07 2016-11-17 Sloan-Kettering Institute For Cancer Research Migrastatins and uses thereof

Also Published As

Publication number Publication date
CA2832439C (en) 2017-08-29
WO2012139074A2 (en) 2012-10-11
JP2016155873A (ja) 2016-09-01
JP5975581B2 (ja) 2016-08-23
EP2693879A4 (en) 2014-10-08
US20160221984A1 (en) 2016-08-04
US9303009B2 (en) 2016-04-05
CN103635088B (zh) 2016-06-15
CN103635088A (zh) 2014-03-12
CA2832439A1 (en) 2012-10-11
US20140024705A1 (en) 2014-01-23
US9546146B2 (en) 2017-01-17
AU2012239977A1 (en) 2013-10-31
EP2693879B1 (en) 2019-01-23
WO2012139074A3 (en) 2012-12-13
AU2012239977B2 (en) 2016-10-20
EP2693879A2 (en) 2014-02-12
JP2014510157A (ja) 2014-04-24

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Legal Events

Date Code Title Description
SREP Specification republished
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired