AU2012219288A1 - Methods for treating diseases of the retina - Google Patents

Methods for treating diseases of the retina Download PDF

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Publication number
AU2012219288A1
AU2012219288A1 AU2012219288A AU2012219288A AU2012219288A1 AU 2012219288 A1 AU2012219288 A1 AU 2012219288A1 AU 2012219288 A AU2012219288 A AU 2012219288A AU 2012219288 A AU2012219288 A AU 2012219288A AU 2012219288 A1 AU2012219288 A1 AU 2012219288A1
Authority
AU
Australia
Prior art keywords
group
het
alkyl
cycloalkyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2012219288A
Other languages
English (en)
Inventor
Eric Beausoleil
Anne-Sophie Casagrande
Laurent J. R. Desire
John E. Donello
Bertrand Leblond
Matthew P. Pando
Veena Viswanath
Rong Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exonhit SA
Allergan Inc
Original Assignee
Exonhit SA
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exonhit SA, Allergan Inc filed Critical Exonhit SA
Publication of AU2012219288A1 publication Critical patent/AU2012219288A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2012219288A 2011-02-18 2012-02-17 Methods for treating diseases of the retina Abandoned AU2012219288A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161444602P 2011-02-18 2011-02-18
US201161444587P 2011-02-18 2011-02-18
US61/444,602 2011-02-18
US61/444,587 2011-02-18
US201161482097P 2011-05-03 2011-05-03
US201161482106P 2011-05-03 2011-05-03
US61/482,097 2011-05-03
US61/482,106 2011-05-03
PCT/US2012/025685 WO2012112918A1 (en) 2011-02-18 2012-02-17 Methods for treating diseases of the retina

Publications (1)

Publication Number Publication Date
AU2012219288A1 true AU2012219288A1 (en) 2013-09-05

Family

ID=45787351

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012219288A Abandoned AU2012219288A1 (en) 2011-02-18 2012-02-17 Methods for treating diseases of the retina

Country Status (7)

Country Link
US (1) US20120214842A1 (enExample)
EP (1) EP2675456A1 (enExample)
JP (1) JP6038051B2 (enExample)
AR (1) AR085285A1 (enExample)
AU (1) AU2012219288A1 (enExample)
CA (1) CA2827509A1 (enExample)
WO (1) WO2012112918A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9790203B2 (en) 2012-11-26 2017-10-17 Abbvie Inc. Inhibitor compounds of phosphodiesterase type 10A
FR3008618A1 (fr) * 2013-07-19 2015-01-23 Univ Paris Curie Utilisation de composes pour restaurer la reponse a la lumiere des cellules de la retine
EP3886854A4 (en) 2018-11-30 2022-07-06 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
WO2021257863A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Pyrrolotriazine compounds as jak2 v617f inhibitors
US11691971B2 (en) 2020-06-19 2023-07-04 Incyte Corporation Naphthyridinone compounds as JAK2 V617F inhibitors
BR112023000047A2 (pt) 2020-07-02 2023-03-14 Incyte Corp Compostos de ureia tricíclicos como inibidores da v617f da jak2
WO2022006456A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic pyridone compounds as jak2 v617f inhibitors
US11661422B2 (en) 2020-08-27 2023-05-30 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
WO2022140231A1 (en) 2020-12-21 2022-06-30 Incyte Corporation Deazaguaine compounds as jak2 v617f inhibitors
AR125273A1 (es) 2021-02-25 2023-07-05 Incyte Corp Lactamas espirocíclicas como inhibidores de jak2 v617f
KR20240163688A (ko) 2022-03-17 2024-11-19 인사이트 코포레이션 Jak2 v617f 억제제로서의 삼환계 우레아 화합물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA012211B1 (ru) 2005-01-07 2009-08-28 Пфайзер Продактс Инк. Гетероароматические соединения хинолинов и их применение в качестве ингибиторов pde10
EP1954128A4 (en) * 2005-11-04 2010-09-22 Merck Sharp & Dohme DIPHENYLMETHANE DERIVATIVES AS AN INHIBITORS OF THE LEUKOTRIEN BIOSYNTHESIS
JP2009535394A (ja) * 2006-05-02 2009-10-01 ファイザー・プロダクツ・インク Ｐｄｅ１０阻害剤としての二環式ヘテロアリール化合物
KR100816670B1 (ko) * 2006-08-18 2008-03-27 국방과학연구소 망막 손상 치료 및 망막 보호하기 위한 메틸렌블루의 용도
PT2125786E (pt) 2006-12-21 2011-04-21 Pfizer Prod Inc Sal succinato de 2-((4-(1-metil-4-(piridin-4-il)-1hpirazol- 3-il)fenoxi)metil)quinolina
US8349830B2 (en) * 2009-10-30 2013-01-08 Merck Sharp & Dohme Aryl aminopyridine PDE10 inhibitors

Also Published As

Publication number Publication date
US20120214842A1 (en) 2012-08-23
WO2012112918A1 (en) 2012-08-23
JP2014506582A (ja) 2014-03-17
EP2675456A1 (en) 2013-12-25
JP6038051B2 (ja) 2016-12-07
AR085285A1 (es) 2013-09-18
CA2827509A1 (en) 2012-08-23

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted