AU2011380507B2 - Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent - Google Patents
Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent Download PDFInfo
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- AU2011380507B2 AU2011380507B2 AU2011380507A AU2011380507A AU2011380507B2 AU 2011380507 B2 AU2011380507 B2 AU 2011380507B2 AU 2011380507 A AU2011380507 A AU 2011380507A AU 2011380507 A AU2011380507 A AU 2011380507A AU 2011380507 B2 AU2011380507 B2 AU 2011380507B2
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
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- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| PCT/US2011/059394 WO2013066349A1 (en) | 2011-11-04 | 2011-11-04 | Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent |
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| CN104602686A (zh) * | 2012-04-13 | 2015-05-06 | 西玛贝医药公司 | 利用卤芬酯或卤芬酸以及抗炎剂治疗痛风患者中高尿酸血症的方法 |
| TWI705812B (zh) | 2014-12-01 | 2020-10-01 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
| JP6368756B2 (ja) * | 2016-10-20 | 2018-08-01 | サイマベイ・セラピューティクス・インコーポレイテッドＣｙｍａＢａｙ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | ハロフェナートまたはハロフェン酸および第２の尿酸低下薬を用いる痛風に罹っている患者の高尿酸血症の治療方法 |
| CN108014108A (zh) * | 2016-11-03 | 2018-05-11 | 江苏万邦生化医药股份有限公司 | lesinurad或其医药上可接受的盐在制备治疗或预防库欣综合征的药物中的应用 |
| WO2019082335A1 (ja) * | 2017-10-26 | 2019-05-02 | 大塚製薬株式会社 | イノシトールリン酸含有組成物 |
| WO2021186250A2 (en) * | 2020-03-15 | 2021-09-23 | Allen Davidoff | Methods of treating viral infections and health consequences |
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| US6262118B1 (en) * | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
| US7576131B2 (en) * | 1999-06-04 | 2009-08-18 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| WO2011032175A1 (en) * | 2009-09-14 | 2011-03-17 | Nuon Therapeutics, Inc. | Combination formulations of tranilast and allopurinol and methods related thereto |
| US9023856B2 (en) * | 2011-11-04 | 2015-05-05 | Cymabay Therapeutics, Inc. | Methods for treating hyperuricemia in patients with gout using halofenate or halogenic acid and a second urate-lowering agent |
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2011
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- 2011-11-04 WO PCT/US2011/059394 patent/WO2013066349A1/en active Application Filing
- 2011-11-04 SG SG11201402032RA patent/SG11201402032RA/en unknown
- 2011-11-04 EP EP11875114.8A patent/EP2773336A4/en not_active Withdrawn
- 2011-11-04 KR KR1020147015169A patent/KR20140121383A/ko not_active Abandoned
- 2011-11-04 CA CA2859686A patent/CA2859686C/en not_active Expired - Fee Related
- 2011-11-04 AU AU2011380507A patent/AU2011380507B2/en not_active Ceased
- 2011-11-04 CN CN201910004813.0A patent/CN109908124A/zh active Pending
- 2011-11-04 JP JP2014541011A patent/JP6202633B2/ja not_active Expired - Fee Related
- 2011-11-04 CN CN201180076191.4A patent/CN104066427A/zh active Pending
- 2011-11-04 NZ NZ624708A patent/NZ624708A/en not_active IP Right Cessation
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2014
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- 2014-05-02 CL CL2014001155A patent/CL2014001155A1/es unknown
- 2014-05-16 ZA ZA2014/03575A patent/ZA201403575B/en unknown
Non-Patent Citations (2)
| Title |
|---|
| "NTC01416402 on 2011_10_21: ClinicalTrials.gov Archive" 21 October 2011Retrieved from the internet:<URL: https://clinicaltrials.gov/archive/NCT01416402/2011_10_21>[retrieved on 2 September 2016] * |
| SAHA, G. C. Arthritis and Rheumatism, vol. 63, no. 10, Suppl. S. October 2011, page S1014 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2859686A1 (en) | 2013-05-10 |
| CA2859686C (en) | 2018-09-11 |
| CN109908124A (zh) | 2019-06-21 |
| EP2773336A4 (en) | 2015-06-03 |
| JP6202633B2 (ja) | 2017-09-27 |
| MX357507B (es) | 2018-07-12 |
| WO2013066349A1 (en) | 2013-05-10 |
| AU2011380507A1 (en) | 2014-05-29 |
| EP2773336A1 (en) | 2014-09-10 |
| JP2014532758A (ja) | 2014-12-08 |
| CN104066427A (zh) | 2014-09-24 |
| IL232386A0 (en) | 2014-06-30 |
| ZA201403575B (en) | 2015-11-25 |
| SG11201402032RA (en) | 2014-09-26 |
| CL2014001155A1 (es) | 2015-01-16 |
| KR20140121383A (ko) | 2014-10-15 |
| NZ624708A (en) | 2015-11-27 |
| MX2014005400A (es) | 2015-02-12 |
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