AU2011219069C1 - Cancer patient selection for administration of therapeutic agents using mass spectral analysis - Google Patents

Cancer patient selection for administration of therapeutic agents using mass spectral analysis Download PDF

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Publication number
AU2011219069C1
AU2011219069C1 AU2011219069A AU2011219069A AU2011219069C1 AU 2011219069 C1 AU2011219069 C1 AU 2011219069C1 AU 2011219069 A AU2011219069 A AU 2011219069A AU 2011219069 A AU2011219069 A AU 2011219069A AU 2011219069 C1 AU2011219069 C1 AU 2011219069C1
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benefit
cancer
patient
treatment
combination
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AU2011219069A1 (en
AU2011219069B2 (en
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Julia Grigorieva
Heinrich Roder
Maxim Tsypin
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Biodesix Inc
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Biodesix Inc
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Priority to AU2014202716A priority Critical patent/AU2014202716B2/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/70Machine learning, data mining or chemometrics
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/40Time-of-flight spectrometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/20Identification of molecular entities, parts thereof or of chemical compositions
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Evolutionary Computation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Software Systems (AREA)
AU2011219069A 2010-02-24 2011-02-22 Cancer patient selection for administration of therapeutic agents using mass spectral analysis Ceased AU2011219069C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014202716A AU2014202716B2 (en) 2010-02-24 2014-05-19 Cancer patient selection for administration of therapeutic agents using mass spectral analysis

Applications Claiming Priority (3)

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US33893810P 2010-02-24 2010-02-24
US61/338,938 2010-02-24
PCT/US2011/000323 WO2011106084A1 (en) 2010-02-24 2011-02-22 Cancer patient selection for administration of therapeutic agents using mass spectral analysis

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AU2011219069A1 AU2011219069A1 (en) 2012-09-13
AU2011219069B2 AU2011219069B2 (en) 2014-02-20
AU2011219069C1 true AU2011219069C1 (en) 2014-07-17

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AU2014202716A Expired - Fee Related AU2014202716B2 (en) 2010-02-24 2014-05-19 Cancer patient selection for administration of therapeutic agents using mass spectral analysis

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US (2) US20110208433A1 (enExample)
EP (1) EP2539704A4 (enExample)
JP (2) JP2013520681A (enExample)
KR (1) KR101556726B1 (enExample)
CN (1) CN102770760A (enExample)
AU (2) AU2011219069C1 (enExample)
CA (1) CA2790928A1 (enExample)
TW (1) TW201142292A (enExample)
WO (1) WO2011106084A1 (enExample)

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JP2015518167A (ja) 2012-05-29 2015-06-25 バイオデシックス・インコーポレイテッドBiodesix Inc 複合的生物試料(例えば、血清)のディープ−malditof質量分析方法およびその使用
WO2014003853A1 (en) * 2012-06-26 2014-01-03 Biodesix, Inc. Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies
US8718996B2 (en) 2012-07-05 2014-05-06 Biodesix, Inc. Method for predicting whether a cancer patient will not benefit from platinum-based chemotherapy agents
US9211314B2 (en) * 2014-04-04 2015-12-15 Biodesix, Inc. Treatment selection for lung cancer patients using mass spectrum of blood-based sample
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CN109212042B (zh) * 2017-06-30 2022-03-04 齐鲁制药有限公司 一种采用液质联用法测定盐酸培唑帕尼基因毒性杂质的分析方法
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Also Published As

Publication number Publication date
WO2011106084A1 (en) 2011-09-01
US20110208433A1 (en) 2011-08-25
JP2013520681A (ja) 2013-06-06
AU2011219069A1 (en) 2012-09-13
KR20130004309A (ko) 2013-01-09
AU2014202716B2 (en) 2016-02-25
KR101556726B1 (ko) 2015-10-02
JP2015222257A (ja) 2015-12-10
CN102770760A (zh) 2012-11-07
CA2790928A1 (en) 2011-09-01
AU2014202716A1 (en) 2014-06-12
AU2011219069B2 (en) 2014-02-20
TW201142292A (en) 2011-12-01
EP2539704A4 (en) 2015-12-02
US20140284468A1 (en) 2014-09-25
EP2539704A1 (en) 2013-01-02

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