AU2010281391B2 - Method of preventing renal disease and treating symptoms thereof - Google Patents

Method of preventing renal disease and treating symptoms thereof Download PDF

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Publication number
AU2010281391B2
AU2010281391B2 AU2010281391A AU2010281391A AU2010281391B2 AU 2010281391 B2 AU2010281391 B2 AU 2010281391B2 AU 2010281391 A AU2010281391 A AU 2010281391A AU 2010281391 A AU2010281391 A AU 2010281391A AU 2010281391 B2 AU2010281391 B2 AU 2010281391B2
Authority
AU
Australia
Prior art keywords
renal disease
subject
symptoms
renal
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2010281391A
Other languages
English (en)
Other versions
AU2010281391A1 (en
Inventor
Margaret Clagett-Dame
Hector F. Deluca
James Wonkee Kim
Lori Plum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
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Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of AU2010281391A1 publication Critical patent/AU2010281391A1/en
Application granted granted Critical
Publication of AU2010281391B2 publication Critical patent/AU2010281391B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2010281391A 2009-08-03 2010-07-28 Method of preventing renal disease and treating symptoms thereof Ceased AU2010281391B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US23086109P 2009-08-03 2009-08-03
US61/230,861 2009-08-03
US25366709P 2009-10-21 2009-10-21
US61/253,667 2009-10-21
PCT/US2010/043551 WO2011017165A1 (en) 2009-08-03 2010-07-28 Method of preventing renal disease and treating symptoms thereof

Publications (2)

Publication Number Publication Date
AU2010281391A1 AU2010281391A1 (en) 2011-12-22
AU2010281391B2 true AU2010281391B2 (en) 2015-05-07

Family

ID=42983794

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010281391A Ceased AU2010281391B2 (en) 2009-08-03 2010-07-28 Method of preventing renal disease and treating symptoms thereof

Country Status (7)

Country Link
US (1) US20110034426A1 (OSRAM)
EP (1) EP2461815B1 (OSRAM)
JP (1) JP5908402B2 (OSRAM)
AU (1) AU2010281391B2 (OSRAM)
CA (1) CA2764577C (OSRAM)
ES (1) ES2524335T3 (OSRAM)
WO (1) WO2011017165A1 (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110237557A1 (en) * 2010-03-23 2011-09-29 Deluca Hector F Diastereomers of 2-methylene-19-nor-22-methyl-1alpha,25-dihydroxyvitamin d3
US8664206B2 (en) 2010-03-23 2014-03-04 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3
US8604009B2 (en) * 2010-03-23 2013-12-10 Wisconsin Alumni Research Foundation (20S)-2-methylene-19-nor-22-dimethyl-1α,25-dihydroxyvitamin D3 and (20R)-2-methylene-19-nor-22-dimethyl-1α,25-hydroxyvitamin D3
HK1206600A1 (en) * 2012-06-29 2016-01-15 Wisconsin Alumni Research Foundation USE OF 2-METHYLENE-19-NOR-(20S)-1α,25-DIHYDROXYVITAMIN D3 TO TREAT SECONDARY HYPERPARATHYROIDISM
US10369161B2 (en) 2014-12-30 2019-08-06 Wisconsin Alumni Research Foundation Use of 2-methylene-19-NOR-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism
US9539264B2 (en) 2014-12-30 2017-01-10 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat secondary hyperparathyroidism in patients previously treated with calcimimetics
WO2017184262A1 (en) * 2016-04-18 2017-10-26 Wisconsin Alumni Research Foundation Use of 2amd and 2md to treat fibrosis

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020028830A1 (en) * 1999-04-29 2002-03-07 Deluca Hector F. Treatment fo systemic lupus erythematosis
US20050187201A1 (en) * 2004-02-19 2005-08-25 Deluca Hector F. Use of 2-methylene-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 for the prophylaxis of bone diseases
US20060003973A1 (en) * 1997-03-17 2006-01-05 Deluca Hector F Use of 2alpha-methyl-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 to increase bone strength
US20060135492A1 (en) * 2000-07-14 2006-06-22 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 to increase bone strength
US7563783B2 (en) * 2005-02-11 2009-07-21 Wisconsin Alumni Research Foundation 2-methylene-19-nor-(20S-24S)-1α,25-dihydroxyvitamin-D2

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843928A (en) 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
AU2001247619A1 (en) * 2000-03-27 2001-10-08 Wisconsin Alumni Research Foundation Vitamin d compounds used to stabilize kidney transplants
US20050124591A1 (en) * 2003-07-29 2005-06-09 Jin Tian Use of vitamin Ds to treat kidney disease
US20060171983A1 (en) * 2003-07-30 2006-08-03 Jin Tian Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease
US7704980B2 (en) * 2003-10-08 2010-04-27 Wisconsin Alumni Research Foundation Treatment of inflammatory bowel disease with 2-methylene-19-nor-vitamin D compounds
ES3047207T3 (en) * 2007-04-25 2025-12-03 Opko Renal Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060003973A1 (en) * 1997-03-17 2006-01-05 Deluca Hector F Use of 2alpha-methyl-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 to increase bone strength
US20020028830A1 (en) * 1999-04-29 2002-03-07 Deluca Hector F. Treatment fo systemic lupus erythematosis
US20060135492A1 (en) * 2000-07-14 2006-06-22 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 to increase bone strength
US20050187201A1 (en) * 2004-02-19 2005-08-25 Deluca Hector F. Use of 2-methylene-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 for the prophylaxis of bone diseases
US7563783B2 (en) * 2005-02-11 2009-07-21 Wisconsin Alumni Research Foundation 2-methylene-19-nor-(20S-24S)-1α,25-dihydroxyvitamin-D2

Also Published As

Publication number Publication date
EP2461815A1 (en) 2012-06-13
WO2011017165A1 (en) 2011-02-10
AU2010281391A1 (en) 2011-12-22
EP2461815B1 (en) 2014-10-22
CA2764577C (en) 2017-12-19
US20110034426A1 (en) 2011-02-10
JP5908402B2 (ja) 2016-04-26
ES2524335T3 (es) 2014-12-05
JP2013501049A (ja) 2013-01-10
CA2764577A1 (en) 2011-02-10
WO2011017165A8 (en) 2011-09-15

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired