AU2009316710B2 - Dimeric 1-arylpyrazole derivatives - Google Patents

Dimeric 1-arylpyrazole derivatives Download PDF

Info

Publication number
AU2009316710B2
AU2009316710B2 AU2009316710A AU2009316710A AU2009316710B2 AU 2009316710 B2 AU2009316710 B2 AU 2009316710B2 AU 2009316710 A AU2009316710 A AU 2009316710A AU 2009316710 A AU2009316710 A AU 2009316710A AU 2009316710 B2 AU2009316710 B2 AU 2009316710B2
Authority
AU
Australia
Prior art keywords
group
independently selected
alkyl
spp
haloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2009316710A
Other languages
English (en)
Other versions
AU2009316710A1 (en
Inventor
Charles Q. Meng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Boehringer Ingelheim Animal Health USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Animal Health USA Inc filed Critical Boehringer Ingelheim Animal Health USA Inc
Publication of AU2009316710A1 publication Critical patent/AU2009316710A1/en
Assigned to MERIAL, INC. reassignment MERIAL, INC. Request for Assignment Assignors: MERIAL LIMITED
Application granted granted Critical
Publication of AU2009316710B2 publication Critical patent/AU2009316710B2/en
Assigned to Boehringer Ingelheim Animal Health USA Inc. reassignment Boehringer Ingelheim Animal Health USA Inc. Request for Assignment Assignors: MERIAL, INC.
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2009316710A 2008-11-19 2009-11-18 Dimeric 1-arylpyrazole derivatives Active AU2009316710B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11602108P 2008-11-19 2008-11-19
US61/116,021 2008-11-19
PCT/US2009/064981 WO2010059719A2 (en) 2008-11-19 2009-11-18 Dimeric 1-arylpyrazole derivatives

Publications (2)

Publication Number Publication Date
AU2009316710A1 AU2009316710A1 (en) 2010-05-27
AU2009316710B2 true AU2009316710B2 (en) 2015-08-06

Family

ID=42034586

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009316710A Active AU2009316710B2 (en) 2008-11-19 2009-11-18 Dimeric 1-arylpyrazole derivatives

Country Status (12)

Country Link
US (1) US8642636B2 (https=)
EP (1) EP2364300B1 (https=)
JP (1) JP2012509338A (https=)
CN (1) CN102264706A (https=)
AU (1) AU2009316710B2 (https=)
BR (1) BRPI0922042B1 (https=)
CA (2) CA2743553C (https=)
EA (1) EA020923B1 (https=)
ES (1) ES2605811T3 (https=)
MX (1) MX2011005214A (https=)
NZ (1) NZ592985A (https=)
WO (1) WO2010059719A2 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012256237B2 (en) 2011-05-13 2017-01-05 Array Biopharma Inc. Pyrrolidinyl urea and pyrrolidinyl thiourea compounds as TrkA kinase inhibitors
US9969694B2 (en) 2012-11-13 2018-05-15 Array Biopharma Inc. N-(arylalkyl)-N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
US9790210B2 (en) 2012-11-13 2017-10-17 Array Biopharma Inc. N-(monocyclic aryl),N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
US9809578B2 (en) 2012-11-13 2017-11-07 Array Biopharma Inc. Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors
WO2014078372A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078408A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
HRP20161613T1 (hr) 2012-11-13 2017-01-13 Array Biopharma, Inc. Tvari bicikličke ureje, tioureje, gvanidina i cijanogvanidina korisne za liječenje boli
WO2014078378A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
US9981959B2 (en) 2012-11-13 2018-05-29 Array Biopharma Inc. Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
MY178262A (en) 2012-11-13 2020-10-07 Array Biopharma Inc Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078328A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-bicyclic aryl,n'-pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
JP2016164125A (ja) * 2013-07-02 2016-09-08 国立大学法人帯広畜産大学 バベシア症の治療剤及び予防剤
CA2949160C (en) 2014-05-15 2023-03-21 Array Biopharma Inc. 1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor
WO2017195173A1 (en) 2016-05-12 2017-11-16 Verdesian Life Sciences, U.S., Llc Compositions for controlling enzyme-induced urea decomposition
CA3058394A1 (en) 2017-03-28 2018-10-04 Verdesian Life Sciences U.S., Llc Triarylmethane compounds for controlling enzyme-induced urea decomposition
PL3876726T3 (pl) * 2018-11-06 2025-04-07 Corteva Agriscience Llc Kompozycje zawierające środki chwastobójcze na bazie pirydynokarboksylanu i środki zabezpieczające na bazie karboksylanu azolu
US12310364B2 (en) 2018-11-06 2025-05-27 Corteva Agriscience Llc Safened compositions comprising pyridine carboxylate herbicides and cloquintocet
HUE070552T2 (hu) 2018-11-07 2025-06-28 Corteva Agriscience Llc Piridin-karboxilát gyomirtót és protoporfirinogén-oxidázt (protox-ot) gátló gyomirtókat tartalmazó készítmények
US12285012B2 (en) 2018-11-07 2025-04-29 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides with acetolactate synthase (ALS) inhibitor herbicides
CA3118565A1 (en) 2018-11-07 2020-05-14 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides with photosystem ii and optional hppd inhibitor herbicides
KR102849990B1 (ko) 2018-11-07 2025-08-27 코르테바 애그리사이언스 엘엘씨 피리딘 카르복실레이트 제초제 및 4-히드록시페닐-피루베이트 디옥시게나아제(hppd) 억제제 제초제를 포함하는 조성물
EP3876727B1 (en) 2018-11-07 2025-07-02 Corteva Agriscience LLC Compositions comprising pyridine carboxylate herbicides with synthetic auxin herbicides or auxin transport inhibitors
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
KR20230043904A (ko) 2020-07-24 2023-03-31 엘랑코 유에스 인코포레이티드 이속사졸린 화합물 및 이의 중간체의 제조 공정
CN116744917A (zh) 2020-09-04 2023-09-12 礼蓝美国公司 适口调配物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966900A (en) * 1969-03-12 1976-06-29 Airwick Industries, Inc. Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator
US20070275976A1 (en) * 2004-06-26 2007-11-29 Stefan Schnatterer N-phenylpyrazole derivatives as pesticides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1939909A (zh) * 1999-12-02 2007-04-04 阿温提斯作物科学股份有限公司 控制动物中的节肢动物
US7262214B2 (en) * 2003-02-26 2007-08-28 Merial Limited 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966900A (en) * 1969-03-12 1976-06-29 Airwick Industries, Inc. Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator
US20070275976A1 (en) * 2004-06-26 2007-11-29 Stefan Schnatterer N-phenylpyrazole derivatives as pesticides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Ahluwalia, V. K., et al, Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1997, 36B, 1059-1061 *
Finar, I. L., et al, Journal of the Chemical Society, 1959, 1819-21 *
Nivorozhkin, A. L., et al, Journal of the Chemical Society, Dalton Transactions, 1996, 1215-1221 *

Also Published As

Publication number Publication date
CA2952443C (en) 2019-04-02
BRPI0922042A2 (pt) 2016-11-01
BRPI0922042B1 (pt) 2020-01-28
US20110245157A1 (en) 2011-10-06
EP2364300A2 (en) 2011-09-14
EA201100800A1 (ru) 2011-12-30
ES2605811T3 (es) 2017-03-16
JP2012509338A (ja) 2012-04-19
CA2743553A1 (en) 2010-05-27
AU2009316710A1 (en) 2010-05-27
EA020923B1 (ru) 2015-02-27
NZ592985A (en) 2013-04-26
HK1160852A1 (en) 2012-08-17
WO2010059719A3 (en) 2010-11-18
US8642636B2 (en) 2014-02-04
CN102264706A (zh) 2011-11-30
MX2011005214A (es) 2011-06-01
EP2364300B1 (en) 2016-10-19
CA2952443A1 (en) 2010-05-27
CA2743553C (en) 2017-03-14
WO2010059719A2 (en) 2010-05-27

Similar Documents

Publication Publication Date Title
AU2009316710B2 (en) Dimeric 1-arylpyrazole derivatives
AU2014342241B2 (en) Antiparasitic and pesticidal isoxazoline compounds
US8426460B2 (en) Dimeric avermectin and milbemycin derivatives
US10653144B2 (en) Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3668866B1 (en) Pesticidal and parasiticidal pyrazole-isoxazoline compounds
HK1160852B (en) Dimeric 1-arylpyrazole derivatives
HK1157790B (en) Dimeric avermectin and milbemycin derivatives

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: MERIAL, INC.

Free format text: FORMER APPLICANT(S): MERIAL LIMITED

FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.

Free format text: FORMER OWNER(S): MERIAL, INC.