AU2009279736A1 - Mesenchymal stromal cell populations and methods of isolating and using same - Google Patents

Mesenchymal stromal cell populations and methods of isolating and using same Download PDF

Info

Publication number
AU2009279736A1
AU2009279736A1 AU2009279736A AU2009279736A AU2009279736A1 AU 2009279736 A1 AU2009279736 A1 AU 2009279736A1 AU 2009279736 A AU2009279736 A AU 2009279736A AU 2009279736 A AU2009279736 A AU 2009279736A AU 2009279736 A1 AU2009279736 A1 AU 2009279736A1
Authority
AU
Australia
Prior art keywords
population
cells
mesenchymal stromal
mscs
stromal cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2009279736A
Other languages
English (en)
Inventor
Claudia Lange
Christopher Westenfelder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALLOCURE Inc
Original Assignee
ALLOCURE Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ALLOCURE Inc filed Critical ALLOCURE Inc
Publication of AU2009279736A1 publication Critical patent/AU2009279736A1/en
Assigned to ALLOCURE, INC. reassignment ALLOCURE, INC. Amend patent request/document other than specification (104) Assignors: ALLOCURE
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/80Undefined extracts from animals
    • C12N2500/84Undefined extracts from animals from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2009279736A 2008-08-04 2009-08-04 Mesenchymal stromal cell populations and methods of isolating and using same Abandoned AU2009279736A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8603308P 2008-08-04 2008-08-04
US61/086,033 2008-08-04
PCT/US2009/052733 WO2010017216A2 (en) 2008-08-04 2009-08-04 Mesenchymal stromal cell populations and methods of isolating and using same

Publications (1)

Publication Number Publication Date
AU2009279736A1 true AU2009279736A1 (en) 2010-02-11

Family

ID=41664170

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009279736A Abandoned AU2009279736A1 (en) 2008-08-04 2009-08-04 Mesenchymal stromal cell populations and methods of isolating and using same

Country Status (6)

Country Link
US (1) US20110293576A1 (https=)
EP (1) EP2321408A4 (https=)
JP (1) JP2011529706A (https=)
AU (1) AU2009279736A1 (https=)
CA (1) CA2736353A1 (https=)
WO (1) WO2010017216A2 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2310006A4 (en) 2008-07-03 2012-04-25 Mayo Foundation CANCER TREATMENT
EP2334785B2 (en) 2008-09-16 2019-08-14 Mayo Foundation For Medical Education And Research Compositions containing platelet contents
WO2011053860A2 (en) * 2009-10-30 2011-05-05 Allocure, Inc. Mesenchymal stromal cell populations and methods of using same
PH12012500892A1 (en) * 2009-11-27 2016-09-09 Stempeutics Res Pvt Ltd Methods of preparing mesenchymal stem cells, compositions and kit thereof
LT2576768T (lt) 2010-06-01 2017-08-25 Auxocell Laboratories, Inc. Gamtinės wharton`s jelly kamieninės ląstelės ir jų gryninimas
US20120087868A1 (en) 2010-10-08 2012-04-12 Gabriele Todd Nanoparticle-loaded cells
AU2012253571A1 (en) 2011-05-09 2014-01-09 Mayo Foundation For Medical Education And Research Cancer treatments
CN104508124B (zh) 2011-07-06 2017-11-17 细胞治疗有限公司 中胚层谱系祖细胞
US20130129688A1 (en) 2011-11-09 2013-05-23 Allocure, Inc. Assay for the Prediction of Therapeutic Effectiveness or Potency of Mesenchymal Stem Cells, and Methods of Using Same
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
SI2785359T1 (sl) 2011-11-30 2018-11-30 Astellas Institute For Regenerative Medicine Mezenhimske stromalne celice in uporabe povezane z njimi
US20130287747A1 (en) 2012-04-30 2013-10-31 Allocure, Inc. Methods of Treating Acute Kidney Injury Using Mesenchymal Stem Cells
HK1208054A1 (en) 2012-07-12 2016-02-19 爱姆斯坦生物技术公司 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
US10413606B2 (en) 2012-10-01 2019-09-17 Mayo Foundation For Medical Education And Research Methods for treating cancer with nanoparticle complexes of albumin-bound paclitaxel and anti-VEGF antibodies
WO2014193895A1 (en) 2013-05-29 2014-12-04 Allocure, Inc. Ex vivo perfusion of donor organs prior to transplantation using mesenchymal stem cells
WO2015014988A1 (en) * 2013-08-01 2015-02-05 Fundacion Pública Andaluza Progreso Y Salud Method for predicting treatment response and test for safe use of mesenchymal stem cells on inflammatory diseases.
EP3143130B1 (en) 2014-05-16 2024-03-06 Mayo Foundation for Medical Education and Research Cell culture media compositions for primary cells
EP3154586B1 (en) 2014-06-13 2020-05-27 Mayo Foundation for Medical Education and Research Treating lymphomas
KR20170020371A (ko) 2014-06-16 2017-02-22 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 골수종의 치료
US9446148B2 (en) 2014-10-06 2016-09-20 Mayo Foundation For Medical Education And Research Carrier-antibody compositions and methods of making and using the same
TW201707725A (zh) 2015-08-18 2017-03-01 美國馬友醫藥教育研究基金會 載體-抗體組合物及其製造及使用方法
TW201713360A (en) 2015-10-06 2017-04-16 Mayo Foundation Methods of treating cancer using compositions of antibodies and carrier proteins
WO2017120501A1 (en) 2016-01-07 2017-07-13 Mayo Foundation For Medical Education And Research Methods of treating cancer with interferon
WO2017139698A1 (en) 2016-02-12 2017-08-17 Mayo Foundation For Medical Education And Research Hematologic cancer treatments
EP3432928A4 (en) 2016-03-21 2019-11-20 Mayo Foundation for Medical Education and Research PROCESS FOR IMPROVING THE THERAPEUTIC INDEX FOR CHEMOTHERAPEUTIC
EP3432926A4 (en) 2016-03-21 2019-11-20 Mayo Foundation for Medical Education and Research METHOD FOR REDUCING THE TOXICITY OF CHEMOTHERAPEUTICS
US10618969B2 (en) 2016-04-06 2020-04-14 Mayo Foundation For Medical Education And Research Carrier-binding agent compositions and methods of making and using the same
WO2018045239A1 (en) 2016-09-01 2018-03-08 Mayo Foundation For Medical Education And Research Carrier-pd-l1 binding agent compositions for treating cancers
JP2019526579A (ja) 2016-09-01 2019-09-19 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチMayo Foundation For Medical Education And Research T細胞癌を標的とする為の方法及び組成物
RU2021128415A (ru) 2016-09-06 2021-11-08 Мэйо Фаундейшн Фор Медикал Эдьюкейшн Энд Рисерч Композиции с паклитакселом, альбумином и связывающим средством и способы их применения и получения
KR20230011473A (ko) 2016-09-06 2023-01-20 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 Pd-l1 발현 암의 치료 방법
EP3509635A1 (en) 2016-09-06 2019-07-17 Vavotar Life Sciences LLC Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins
US20190060365A1 (en) * 2017-08-25 2019-02-28 Meridigen Biotech Co., Ltd. Pharmaceutical composition for treating chronic obstructive pulmonary disease and method thereof
SG11202004680UA (en) 2017-11-22 2020-06-29 Mesoblast Int Sarl Cellular compositions and methods of treatment i
KR20220031555A (ko) 2019-06-11 2022-03-11 옥소젠 코포레이션 조직의 습식 보존
JP7582958B2 (ja) * 2019-09-30 2024-11-13 テルモ株式会社 凍結保存細胞の希釈用緩衝液
EP4190892A4 (en) * 2020-07-31 2024-10-30 Rainbow Inc. Platelet lysate derived from autologous platelets
EP4316498A4 (en) 2021-03-30 2025-03-26 Kaneka Corporation Trypsin inhibition method, and method for producing cell preparation in which same is used

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0501462L (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
WO2008034803A1 (en) * 2006-09-18 2008-03-27 Medizinische Universität Graz Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics

Also Published As

Publication number Publication date
CA2736353A1 (en) 2010-02-11
EP2321408A2 (en) 2011-05-18
WO2010017216A2 (en) 2010-02-11
WO2010017216A3 (en) 2010-06-17
JP2011529706A (ja) 2011-12-15
EP2321408A4 (en) 2013-04-17
US20110293576A1 (en) 2011-12-01
WO2010017216A8 (en) 2010-09-30

Similar Documents

Publication Publication Date Title
US20110293576A1 (en) Mesenchymal stromal cell populations and methods of isolating and using same
US20120269779A1 (en) Mesenchymal stromal cell populations and methods of using same
US20140335058A1 (en) Assay for the prediction of therapeutic effectiveness of mesenchymal stromal cells, and methods of using same
US20260007702A1 (en) Stem cell therapy based on adipose-derived stem cells
US10874698B2 (en) Therapy using cardiac stem cells and mesenchymal stem cells
WO2008148105A1 (en) Endometrial stem cells and methods of making and using same
US20130129688A1 (en) Assay for the Prediction of Therapeutic Effectiveness or Potency of Mesenchymal Stem Cells, and Methods of Using Same
US20120100108A1 (en) Compositions and methods of treating no-option critical limb ischemia (cli)
CN114901806B (zh) 细胞群以及其取得方法
WO2014193895A1 (en) Ex vivo perfusion of donor organs prior to transplantation using mesenchymal stem cells
EP2205251B1 (en) A method to amplify cardiac stem cells in vitro and in vivo
RU2314816C2 (ru) Биотрансплантат, содержащий ядросодержащие клетки костного мозга, в том числе преддифференцированные в эндотелиальном и кардиомиоцитарном направлении, способ его получения (варианты) и способ лечения сердечной недостаточности (варианты)
WO2024133886A1 (en) Primed mesenchymal stem cells for use in the treatment of chronic kidney disease
HK1259517A1 (en) Stem cell therapy based on adipose-derived stem cells
HK1259517B (en) Stem cell therapy based on adipose-derived stem cells

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application