AU2009238686B2 - Chromatography medium - Google Patents

Chromatography medium Download PDF

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Publication number
AU2009238686B2
AU2009238686B2 AU2009238686A AU2009238686A AU2009238686B2 AU 2009238686 B2 AU2009238686 B2 AU 2009238686B2 AU 2009238686 A AU2009238686 A AU 2009238686A AU 2009238686 A AU2009238686 A AU 2009238686A AU 2009238686 B2 AU2009238686 B2 AU 2009238686B2
Authority
AU
Australia
Prior art keywords
chromatography medium
lid
molecules
core
ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2009238686A
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English (en)
Other versions
AU2009238686A1 (en
Inventor
Jan Bergstrom
Gunnar Glad
Bo-Lennart Johansson
Jean-Luc Maloisel
Nils Norrman
Tobias E. Soderman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytiva Bioprocess R&D AB
Original Assignee
Cytiva Bioprocess R&D AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytiva Bioprocess R&D AB filed Critical Cytiva Bioprocess R&D AB
Publication of AU2009238686A1 publication Critical patent/AU2009238686A1/en
Application granted granted Critical
Publication of AU2009238686B2 publication Critical patent/AU2009238686B2/en
Assigned to GE HEALTHCARE BIOPROCESS R&D AB reassignment GE HEALTHCARE BIOPROCESS R&D AB Request for Assignment Assignors: GE HEALTHCARE BIO-SCIENCES AB
Assigned to CYTIVA BIOPROCESS R&D AB reassignment CYTIVA BIOPROCESS R&D AB Request to Amend Deed and Register Assignors: GE HEALTHCARE BIOPROCESS R&D AB
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28009—Magnetic properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287—Non-polar phases; Reversed phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
AU2009238686A 2008-04-22 2009-04-21 Chromatography medium Active AU2009238686B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0800923-5 2008-04-22
SE0800923 2008-04-22
PCT/SE2009/050406 WO2009131526A1 (en) 2008-04-22 2009-04-21 Chromatography medium

Publications (2)

Publication Number Publication Date
AU2009238686A1 AU2009238686A1 (en) 2009-10-29
AU2009238686B2 true AU2009238686B2 (en) 2014-08-28

Family

ID=41217058

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009238686A Active AU2009238686B2 (en) 2008-04-22 2009-04-21 Chromatography medium

Country Status (7)

Country Link
US (4) US20110045574A1 (enExample)
EP (1) EP2268393A4 (enExample)
JP (1) JP5643747B2 (enExample)
CN (1) CN102015094B (enExample)
AU (1) AU2009238686B2 (enExample)
DE (1) DE09735164T1 (enExample)
WO (1) WO2009131526A1 (enExample)

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JP5643747B2 (ja) 2008-04-22 2014-12-17 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ クロマトグラフィー媒体
US20110142863A1 (en) * 2009-12-16 2011-06-16 Millipore Corporation Flow through purification processes for large biomolecules
IN2012DN06243A (enExample) * 2010-02-19 2015-09-25 Ge Healthcare Bio Sciences Ab
WO2012134381A1 (en) * 2011-03-31 2012-10-04 Ge Healthcare Bio-Sciences Ab Method and means for sample preparation
US9260536B2 (en) 2011-07-22 2016-02-16 Stellan Hjerten Capture of pathogenic and non-pathogenic biopolymers and bioparticles
WO2013130001A1 (en) * 2012-02-29 2013-09-06 Ge Healthcare Bio-Sciences Ab Method for endotoxin removal
US10041050B2 (en) 2012-02-29 2018-08-07 Ge Healthcare Bioprocess R&D Ab Method for endotoxin removal
US9782468B2 (en) 2013-05-20 2017-10-10 Shantha Biotechnics Private Limited Purification of polysaccharide protein conjugates
DK3043904T3 (en) 2013-09-09 2018-03-26 Lab On A Bead Ab MAGNETIC PARTICLES FOR SEPARATION AND ANALYSIS OF MOLECULES AND CELLS AND PROCEDURE FOR MANUFACTURING THESE PARTICLES
WO2015137860A1 (en) * 2014-03-14 2015-09-17 Ge Healthcare Bio-Sciences Ab Separation matrices for purification of biological particles
US10626164B2 (en) 2014-07-25 2020-04-21 Csl Limited Purification of VWF
GB201506117D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
GB201506113D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
EP3353193A4 (en) * 2015-09-22 2019-04-03 Sanofi Pasteur Biologics, LLC CLEANING OF THE RESPIRATORY SYNZYTIAL VIRUS
ES2986551T3 (es) * 2016-04-06 2024-11-11 Cytiva Bioprocess R & D Ab Matriz de cromatografía
EP4574227A3 (en) 2016-09-29 2025-09-03 Bio-Rad Laboratories, Inc. Protein-nanoparticle conjugate purification methods
US10814305B2 (en) 2016-09-29 2020-10-27 Bio-Rad Laboratories, Inc. Agarose-filled ceramic apatite
KR102071507B1 (ko) * 2018-03-26 2020-01-30 국민대학교산학협력단 바이오센서용 하이드로겔 구조체, 이를 포함하는 바이오센서, 및 상기 바이오센서용 하이드로겔 구조체의 제조방법
GB201806736D0 (en) * 2018-04-25 2018-06-06 Ge Healthcare Bioprocess R&D Ab Method for virus purification
JP7577538B2 (ja) 2020-02-19 2024-11-05 バイオ－ラッド ラボラトリーズ インコーポレーティッド ポリマー充填クロマトグラフィー樹脂を調製する方法
CN111420644A (zh) * 2020-03-27 2020-07-17 北京石油化工学院 一种复合型混合模式聚合物层析介质的制备方法
CN113416235B (zh) * 2021-06-24 2023-04-25 苏州赛分科技股份有限公司 用于纯化分离病毒类抗原的液相色谱法
US20240198316A1 (en) * 2021-05-31 2024-06-20 Suzhou Sepax Technologies, Inc. Synthetic polymeric porous medium with hierarchical multiple layer structure, its design, synthesis, modification, and liquid chromatographic applications
US20260028597A1 (en) 2022-12-27 2026-01-29 Cytiva Bioprocess R&D Ab Purification of biological particles
EP4694993A1 (en) 2023-04-12 2026-02-18 Cytiva BioProcess R&D AB A chromatography system, use thereof, and a method for separating enveloped or membranous biological particles

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EP1764152A1 (en) * 2005-09-19 2007-03-21 Millipore Corporation Asymmetric porous adsorptive bead
WO2009014481A1 (en) * 2007-07-25 2009-01-29 Ge Healthcare Bio-Sciences Ab Separation matrix

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US20050267295A1 (en) * 1999-11-25 2005-12-01 Makonnen Belew Method for selective removal of a substance from samples containing compounds having nucleic acid structure
EP1764152A1 (en) * 2005-09-19 2007-03-21 Millipore Corporation Asymmetric porous adsorptive bead
WO2009014481A1 (en) * 2007-07-25 2009-01-29 Ge Healthcare Bio-Sciences Ab Separation matrix

Also Published As

Publication number Publication date
WO2009131526A1 (en) 2009-10-29
CN102015094A (zh) 2011-04-13
EP2268393A4 (en) 2013-08-14
US20220266170A1 (en) 2022-08-25
DE09735164T1 (de) 2024-06-20
US20200101398A1 (en) 2020-04-02
JP2011518337A (ja) 2011-06-23
US10493380B2 (en) 2019-12-03
US11439926B2 (en) 2022-09-13
JP5643747B2 (ja) 2014-12-17
EP2268393A1 (en) 2011-01-05
US20170050121A1 (en) 2017-02-23
AU2009238686A1 (en) 2009-10-29
US20110045574A1 (en) 2011-02-24
CN102015094B (zh) 2016-11-09

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: GE HEALTHCARE BIOPROCESS R&D AB

Free format text: FORMER OWNER WAS: GE HEALTHCARE BIO-SCIENCES AB

HB Alteration of name in register

Owner name: CYTIVA BIOPROCESS R&D AB

Free format text: FORMER NAME(S): GE HEALTHCARE BIOPROCESS R&D AB