AU2009207579A1 - Abuse resistant melt extruded formulation having reduced alcohol interaction - Google Patents
Abuse resistant melt extruded formulation having reduced alcohol interaction Download PDFInfo
- Publication number
- AU2009207579A1 AU2009207579A1 AU2009207579A AU2009207579A AU2009207579A1 AU 2009207579 A1 AU2009207579 A1 AU 2009207579A1 AU 2009207579 A AU2009207579 A AU 2009207579A AU 2009207579 A AU2009207579 A AU 2009207579A AU 2009207579 A1 AU2009207579 A1 AU 2009207579A1
- Authority
- AU
- Australia
- Prior art keywords
- drug
- ethanol
- melt
- verapamil
- dosage form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2328808P | 2008-01-24 | 2008-01-24 | |
| US61/023,288 | 2008-01-24 | ||
| PCT/EP2009/050853 WO2009092818A1 (fr) | 2008-01-24 | 2009-01-26 | Formulation extrudée à l’état fondu contre l’abus ayant une interaction réduite avec l’alcool |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2009207579A1 true AU2009207579A1 (en) | 2009-07-30 |
Family
ID=40524758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2009207579A Abandoned AU2009207579A1 (en) | 2008-01-24 | 2009-01-26 | Abuse resistant melt extruded formulation having reduced alcohol interaction |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP2254553A1 (fr) |
| JP (1) | JP2011510048A (fr) |
| KR (1) | KR20100110370A (fr) |
| CN (1) | CN101977592A (fr) |
| AU (1) | AU2009207579A1 (fr) |
| BR (1) | BRPI0907402A2 (fr) |
| CA (1) | CA2713373A1 (fr) |
| IL (1) | IL207173A0 (fr) |
| MX (1) | MX2010008100A (fr) |
| NZ (1) | NZ586962A (fr) |
| TW (1) | TW200950776A (fr) |
| WO (1) | WO2009092818A1 (fr) |
| ZA (1) | ZA201005797B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100172989A1 (en) * | 2006-01-21 | 2010-07-08 | Abbott Laboratories | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| US20090317355A1 (en) * | 2006-01-21 | 2009-12-24 | Abbott Gmbh & Co. Kg, | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| ES2692437T3 (es) | 2007-08-13 | 2018-12-03 | Abuse Deterrent Pharmaceutical Llc | Fármacos resistentes al abuso, método de uso y método de preparación |
| AT511581A1 (de) | 2011-05-26 | 2012-12-15 | G L Pharma Gmbh | Orale retardierende formulierung |
| US20140275149A1 (en) | 2013-03-15 | 2014-09-18 | Inspirion Delivery Technologies, Llc | Abuse deterrent compositions and methods of use |
| US10729685B2 (en) | 2014-09-15 | 2020-08-04 | Ohemo Life Sciences Inc. | Orally administrable compositions and methods of deterring abuse by intranasal administration |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| JP2022522270A (ja) | 2019-03-01 | 2022-04-15 | フラメル アイルランド リミテッド | 食事摂取状態における改善された薬物動態を有するガンマ－ヒドロキシ酪酸塩組成物 |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| DE10208344A1 (de) * | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
| TWI350762B (en) * | 2004-02-12 | 2011-10-21 | Euro Celtique Sa | Particulates |
| JP5704789B2 (ja) * | 2005-01-28 | 2015-04-22 | ユーロ−セルティーク エス．エイ． | 耐アルコール性剤形 |
| EP1693045A1 (fr) * | 2005-02-17 | 2006-08-23 | Abbott GmbH & Co. KG | Production de formes posologiques à partir de substances actives fondues |
| JP2009523833A (ja) * | 2006-01-21 | 2009-06-25 | アボット ゲーエムベーハー ウント カンパニー カーゲー | 乱用薬剤送達のための製剤および方法 |
-
2009
- 2009-01-23 TW TW098103158A patent/TW200950776A/zh unknown
- 2009-01-26 NZ NZ586962A patent/NZ586962A/en not_active IP Right Cessation
- 2009-01-26 CN CN2009801104128A patent/CN101977592A/zh active Pending
- 2009-01-26 MX MX2010008100A patent/MX2010008100A/es not_active Application Discontinuation
- 2009-01-26 CA CA2713373A patent/CA2713373A1/fr not_active Abandoned
- 2009-01-26 KR KR1020107018601A patent/KR20100110370A/ko not_active Application Discontinuation
- 2009-01-26 AU AU2009207579A patent/AU2009207579A1/en not_active Abandoned
- 2009-01-26 WO PCT/EP2009/050853 patent/WO2009092818A1/fr active Application Filing
- 2009-01-26 EP EP09704585A patent/EP2254553A1/fr not_active Withdrawn
- 2009-01-26 BR BRPI0907402-3A patent/BRPI0907402A2/pt not_active IP Right Cessation
- 2009-01-26 JP JP2010543521A patent/JP2011510048A/ja active Pending
-
2010
- 2010-07-22 IL IL207173A patent/IL207173A0/en unknown
- 2010-08-13 ZA ZA2010/05797A patent/ZA201005797B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2254553A1 (fr) | 2010-12-01 |
| KR20100110370A (ko) | 2010-10-12 |
| IL207173A0 (en) | 2010-12-30 |
| CA2713373A1 (fr) | 2009-07-30 |
| MX2010008100A (es) | 2010-12-21 |
| TW200950776A (en) | 2009-12-16 |
| NZ586962A (en) | 2012-07-27 |
| ZA201005797B (en) | 2011-04-28 |
| JP2011510048A (ja) | 2011-03-31 |
| BRPI0907402A2 (pt) | 2015-07-21 |
| WO2009092818A1 (fr) | 2009-07-30 |
| CN101977592A (zh) | 2011-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: ABBVIE DEUTSCHLAND GMBH & CO. KG Free format text: FORMER APPLICANT(S): ABBOTT GMBH & CO., KG |
|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |